Gliosarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-23Clinical Trial Update: Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma [Phase 3]
Phase 3 trial update evaluating adding lomustine to standard temozolomide and radiation for newly diagnosed MGMT-methylated glioblastoma; st…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Association of Peripheral Blood Immunologic Response to Therapeutic Response to Adjuvant Treatment With Immune Checkpoint Inhibition (ICI) in Patients With Newly Diagnosed Glioblastoma or Gliosarcoma [Phase 2]
A Phase 2 clinical trial update exploring whether peripheral blood immunologic biomarkers predict response to adjuvant immune checkpoint inh…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent Glioma [Phase 1]
This clinical trial investigates temozolomide (Temodar) in combination with the HDAC inhibitor Abexinostat for recurrent high-grade gliomas,…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Ultrasound-based Blood-brain Barrier Opening and Albumin-bound Paclitaxel and Carboplatin for Recurrent Glioblastoma [Phase 1, Phase 2]
An update on a Phase 1/2 clinical trial evaluating ultrasound-induced opening of the blood-brain barrier in combination with albumin-bound p…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Vorinostat and Temozolomide in Treating Patients With Malignant Gliomas [Phase 1]
Phase 1 clinical trial update exploring vorinostat with temozolomide for malignant gliomas in adults, with active-not-recruiting status acro…
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CLINICAL_TRIALS other · 2026-04-13Clinical Trial Update: Testing the Combination of Anti-cancer Drugs Actimab-A and Cemiplimab (REGN2810) to Improve Outcomes for Patients With Recurrent Glioblastoma [Phase 1]
This clinical trial update describes a Phase 1 study evaluating the combination of Actimab-A and cemiplimab (REGN2810) for recurrent gliobla…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Study Assessing if it is Safe and Possible to Treat Brain Cancer Patients With Immunotherapy Before They Receive the Standard Treatment. [Phase 1]
A Phase 1 trial is evaluating whether immunotherapy can be safely given to adults with glioblastoma or gliosarcoma before their standard tre…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma [Phase 2]
Clinical trial update for a Phase 2 study evaluating GI-102 alone or with pembrolizumab before surgery in patients with recurrent or progres…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma [Phase 3]
A Phase 3 trial is evaluating adding lomustine to standard temozolomide and radiation therapy for newly diagnosed MGMT-methylated glioblasto…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: DSC-MRI in Measuring rCBV for Early Response to Bevacizumab in Patients With Recurrent Glioblastoma [NA]
This clinical trial update discusses the use of DSC-MRI derived rCBV to measure early response to bevacizumab in patients with recurrent gli…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: Study of ABBV-637 or ABBV-155 With ERAS-801 for People With Glioblastoma [Phase 1]
Phase 1 trial evaluating ABBV-637 or ABBV-155 in combination with ERAS-801 for glioblastoma and gliosarcoma is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Pembrolizumab and Standard Therapy in Treating Patients With Glioblastoma [Phase 2]
Phase 2 clinical trial assessing pembrolizumab with standard therapy for glioblastoma and gliosarcoma; status update indicates ongoing or co…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma [Phase 1]
Phase 1 trial evaluating mesenchymal stem cell-delivered DNX-2401 for recurrent high-grade glioma. The study is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Improving Understanding of Glioblastoma Through Preservation of Biologically Active Brain Tissue
This entry provides an update on an ongoing clinical trial aimed at improving understanding of glioblastoma by preserving biologically activ…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Phase I CB-NK-TGF-ßR2-/NR3C1- in rGBM [Phase 1]
A Phase I clinical trial update for CB-NK-TGF-ßR2-/NR3C1- therapy in recurrent gliosarcoma and recurrent supratentorial glioblastoma, curren…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Re-Administration of C134 in Patients With Recurrent GBM (C134-HSV-1) [Phase 1]
Phase 1 study evaluating re-administration of C134 in patients with recurrent glioblastoma and related brain gliomas has been terminated.
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Study of Pembrolizumab and M032 (NSC 733972) [Phase 1, Phase 2]
A Phase 1/2 clinical trial update evaluating pembrolizumab in combination with M032 for glioblastoma, anaplastic astrocytoma, and gliosarcom…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Efineptakin Alfa and Pembrolizumab for the Treatment of Recurrent Glioblastoma [Phase 2]
A Phase 2 clinical trial is investigating the combination of efineptakin alfa with pembrolizumab for recurrent glioblastoma and related high…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Natural Progesterone for the Treatment of Recurrent Glioblastoma [EARLY_Phase 1]
A Phase 1 study of natural progesterone for recurrent glioblastoma and gliosarcoma is being conducted by Emory University, with status liste…
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CLINICAL_TRIALS trial_result · 2025-12-31Clinical Trial Update: Dose Escalation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma [Phase 1]
Phase 1 dose-escalation trial of re-irradiation in good-prognosis recurrent glioblastoma has completed.
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Atezolizumab and Cabozantinib for the Treatment of Recurrent Glioblastoma [Phase 1, Phase 2]
A phase 1/2 clinical trial is evaluating the combination of atezolizumab and cabozantinib for recurrent glioblastoma and recurrent gliosarco…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: hSTAR GBM (Hematopoetic Stem Cell (HPC) Rescue for GBM) [Phase 2]
A Phase 2 clinical trial evaluating hematopoietic stem cell rescue for glioblastoma (hSTAR GBM) is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Phase I Pilot Study to Evaluate the Anti-glioblastoma Effect of S-Gboxin in Standard Treatment of Glioblastoma/Diffuse Midline Glioma and Response to Treatment (Regardless of Mutation Status) [Phase 1]
A Phase I pilot study evaluating S-Gboxin in combination with standard glioblastoma therapy; the trial assessing anti-glioblastoma effects i…
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CLINICAL_TRIALS trial_result · 2025-11-13Clinical Trial Update: Testing the Ability of AMG 232 (KRT 232) to Get Into the Tumor in Patients With Brain Cancer [Phase 1]
A Phase 1 clinical trial of AMG 232 (KRT-232) in patients with brain cancers including glioblastoma and gliosarcoma was terminated; the stud…
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: Peposertib and Radiation Therapy, Followed by Temozolomide for the Treatment of Patients With Newly Diagnosed MGMT Unmethylated Glioblastoma or Gliosarcoma [Phase 1]
Phase 1 trial evaluating peposertib with radiation therapy followed by temozolomide for newly diagnosed MGMT unmethylated glioblastoma or gl…