Gliosarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Phase 2a Immune Modulation With Ultrasound for Newly Diagnosed Glioblastoma [Phase 2]
This clinical trial entry notes a Phase 2a study from Northwestern University evaluating ultrasound-based immune modulation for newly diagno…
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CLINICAL_TRIALS trial_result · 2025-09-24Clinical Trial Update: Atezolizumab in Combination With Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating atezolizumab in combination with temozolomide and radiation therapy for newly diagnosed glioblastoma has…
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma [EARLY_Phase 1]
Early-phase study evaluating the use of 18F-FDOPA PET imaging to plan surgery and radiation therapy for adults with newly diagnosed malignan…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: A Phase IB 2 Dose Trial of IRS-1 HSV C134 (IND 17296) Administered Intratumorally in Patients With Recurrent Malignant Glioma [Phase 1]
This is a Phase Ib dose-escalation trial evaluating intratumoral administration of IRS-1 HSV C134 in patients with recurrent malignant gliom…
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CLINICAL_TRIALS trial_result · 2025-08-03Clinical Trial Update: Spectroscopic MRI-Guided Radiation Therapy Planning in Glioblastoma [Phase 2]
A Phase 2 trial evaluating spectroscopic MRI-guided radiation therapy planning for glioblastoma and gliosarcoma has completed with results p…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Prognostic Potential of Olfactory Function in Glioblastoma: a Prospective Observational Study
This prospective observational study investigates whether olfactory function can serve as a prognostic indicator in adults with glioblastoma…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Trial of C134 in Patients With Recurrent GBM [Phase 1]
Phase 1 clinical trial update for C134 in recurrent glioblastoma and related brain cancers reports results with results posted on 2025-07-03…
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: Mycophenolate Mofetil Combined With Radiation Therapy in Glioblastoma [Phase 1]
Phase 1 clinical trial evaluating mycophenolate mofetil in combination with radiation therapy for glioblastoma and related astrocytomas; the…
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Tinostamustine With or Without Radiation Therapy in Treating Patients With Newly Diagnosed MGMT-Unmethylated Glioblastoma [Phase 1]
Phase 1 trial evaluating tinostamustine with or without radiation therapy in newly diagnosed MGMT-unmethylated glioblastoma; the study has c…
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CLINICAL_TRIALS withdrawal · 2025-05-07Clinical Trial Update: Temozolomide, Memantine Hydrochloride, Mefloquine, and Metformin Hydrochloride in Treating Patients With Glioblastoma Multiforme After Radiation Therapy [Phase 1]
A Phase 1 trial evaluating a combination of temozolomide, memantine hydrochloride, mefloquine, and metformin hydrochloride in glioblastoma m…
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: ERC1671/GM-CSF/Cyclophosphamide for the Treatment of Glioblastoma Multiforme [Phase 2]
Phase 2 clinical trial update for ERC1671 in combination with GM-CSF and cyclophosphamide for glioblastoma multiforme and gliosarcoma. The s…
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: NovoTTF-100A With Bevacizumab (Avastin) in Patients With Recurrent Glioblastoma [Phase 2]
Phase 2 trial evaluating NovoTTF-100A (tumor treating fields) combined with bevacizumab in recurrent glioblastoma has completed with results…
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CLINICAL_TRIALS trial_result · 2025-01-15Clinical Trial Update: Partial Brain RT, Temozolomide, Chloroquine, and TTF Therapy for the Treatment of Newly Diagnosed Glioblastoma [Phase 1]
A Phase 1 trial combining partial brain radiotherapy, temozolomide, chloroquine, and tumor treating fields for newly diagnosed glioblastoma …
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CLINICAL_TRIALS trial_result · 2024-11-06Clinical Trial Update: Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma [Phase 1]
A Phase 1 trial evaluating Lapatinib Ditosylate before surgical resection in adults with recurrent high-grade glioma has completed. The stud…
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CLINICAL_TRIALS research · 2024-10-17Clinical Trial Update: Lonafarnib and Temozolomide in Treating Patients with Glioblastoma Multiforme That is Recurrent or Did Not Respond to Previous Treatment with Temozolomide [Phase 1]
Phase 1 trial update evaluating lonafarnib in combination with temozolomide for recurrent glioblastoma multiforme and related gliomas.
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed Glioblastoma [Phase 1]
Phase 1 trial evaluating selinexor in combination with temozolomide and radiation therapy for newly diagnosed glioblastoma (and gliosarcoma)…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Bevacizumab and Temozolomide in Treating Older Patients With Newly-Diagnosed Glioblastoma Multiforme or Gliosarcoma [Phase 2]
This Phase 2 trial evaluating bevacizumab with temozolomide in older patients with newly diagnosed glioblastoma or gliosarcoma has completed…
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: Whole Brain Radiation Therapy With Standard Temozolomide Chemo-Radiotherapy and Plerixafor in Treating Patients With Glioblastoma [Phase 2]
A Phase 2 clinical trial assessing the addition of plerixafor to standard temozolomide-based chemoradiotherapy for glioblastoma has complete…
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CLINICAL_TRIALS trial_result · 2024-05-01Clinical Trial Update: Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma [Phase 2, Phase 3]
This update reports the results of a randomized Phase 2/3 trial comparing ipilimumab and nivolumab with radiation therapy versus the standar…
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CLINICAL_TRIALS trial_result · 2024-04-29Clinical Trial Update: Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas [Phase 1]
Phase 1 clinical trial update evaluating safety and preliminary efficacy of carboxylesterase-expressing allogeneic neural stem cells in comb…
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CLINICAL_TRIALS trial_result · 2024-04-08Clinical Trial Update: Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children [Phase 1]
Phase 1b trial update for PVSRIPO in recurrent malignant glioma in children has completed enrollment and results posted.
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CLINICAL_TRIALS trial_result · 2024-03-06Clinical Trial Update: Study of Binimetinib With Encorafenib in Adults With Recurrent BRAF V600-Mutated HGG [Phase 2]
A Phase 2 study of the MEK inhibitor binimetinib plus the BRAF inhibitor encorafenib in adults with recurrent BRAF V600-mutant high-grade gl…
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CLINICAL_TRIALS trial_result · 2024-02-02Clinical Trial Update: Genetically Engineered HSV-1 Phase 1 Study for the Treatment of Recurrent Malignant Glioma [Phase 1]
This entry describes a Phase 1 clinical trial of a genetically engineered HSV-1 therapy for recurrent malignant glioma, including glioblasto…
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CLINICAL_TRIALS trial_result · 2024-01-03Clinical Trial Update: Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas [Phase 1]
Phase 1 trial evaluating adavosertib with local radiation in children with newly diagnosed diffuse intrinsic pontine glioma; results are pos…
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CLINICAL_TRIALS trial_result · 2023-05-22Clinical Trial Update: Phase I/II Trial of AXL1717 in the Treatment of Recurrent Malignant Astrocytomas [Phase 1, Phase 2]
Phase I/II trial of AXL1717 in recurrent malignant astrocytomas (glioblastoma, gliosarcoma) with terminated status and results posted.