Glioblastoma
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Music Therapy in Newly Diagnosed Glioblastoma After Chemoradiation Therapy (MELODY-GBM) [NA]
A feasibility study (MELODY-GBM) evaluating music therapy for patients with newly diagnosed glioblastoma after chemoradiation is not yet rec…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Pembrolizumab and Standard Therapy in Treating Patients With Glioblastoma [Phase 2]
Phase 2 clinical trial assessing pembrolizumab with standard therapy for glioblastoma and gliosarcoma; status update indicates ongoing or co…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Multiparametric MR-Guided High Dose Adaptive Radiotherapy With Concurrent Temozolomide in Patients With Newly Diagnosed Glioblastoma [Phase 2]
Update on a Phase 2 trial evaluating multiparametric MRI-guided high-dose adaptive radiotherapy with concurrent temozolomide for newly diagn…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Hypofractionated Radiotherapy Plus Temozolamide in Patients Younger Than 70 Years With Glioblastoma [NA]
A clinical trial is evaluating hypofractionated radiotherapy plus temozolomide in patients younger than 70 with glioblastoma. The study stat…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Pilot Study Evaluating Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Intracranial Lesions During Neurosurgical Procedures [EARLY_Phase 1]
This document describes a NOT_YET_RECRUITING Phase 1 pilot study evaluating Panitumumab-IRDye800 as an optical imaging agent to detect intra…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Safety and Efficacy Study of TX103 CAR-T Cell Therapy for Recurrent or Progressive Grade 4 Glioma. [Phase 1]
This Phase 1 study is evaluating the safety and efficacy of TX103 CAR-T cell therapy in patients with recurrent or progressive Grade 4 gliom…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Glioma Modified Atkins-based Diet in Patients With Glioblastoma [NA]
A clinical trial examining a Modified Atkins diet for patients with glioblastoma has completed (status: COMPLETED).
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Clinical Study of a Novel Oncolytic Virus Ad-TD-nsIL12 in the Treatment of Primary High-grade Glioma [Phase 1, Phase 2]
Clinical trial update for Ad-TD-nsIL12, an oncolytic virus, in primary high-grade glioma, currently in Phase 1/Phase 2 and enrolling by invi…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Safety and Efficacy of CTX-009 With or Without CTX-471 for Recurrent Glioblastoma [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial is evaluating CTX-009 with or without CTX-471 for recurrent glioblastoma; recruitment has not yet begun.
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: A Study for Cerebral Open Flow Microperfusion [NA]
A Mayo Clinic study evaluating cerebral open flow microperfusion for glioma and glioblastoma is listed as not yet recruiting.
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors [Phase 1]
Phase 1 clinical trial update evaluating the safety and tolerability of the radiopharmaceutical 212Pb-DOTAM-GRPR1 in adults with recurrent o…
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption [NA]
This completed study evaluated the safety and feasibility of ExAblate–mediated blood-brain barrier disruption in glioma and glioblastoma.
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Phase 0/2 PD-Trigger Study of BGB-58067 in Newly Diagnosed Glioblastoma Patients With MTAP-Deleted Tumors [EARLY_Phase 1]
An early-phase Phase 0/2 trial evaluating BGB-58067 in newly diagnosed glioblastoma with MTAP deletion; the study is currently not yet recru…
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Exablate Blood-Brain Barrier Disruption for the Treatment of rGBM in Subjects Undergoing Carboplatin Monotherapy [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluating Exablate Blood-Brain Barrier disruption for recurrent glioblastoma in patients receiving carboplatin …
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma [Phase 1]
This is a Phase 1 safety and dose-finding trial of GLIX1 in adults with recurrent or progressive high-grade glioma, currently not yet recrui…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Adjuvant Temozolomide ± 5-Aminolevulinic Acid + Low Intensity Diffuse Ultrasound Sonodynamic Therapy System for Newly Diagnosed Glioblastoma [Phase 2]
Phase 2 clinical trial update for newly diagnosed glioblastoma evaluating adjuvant temozolomide with optional 5-aminolevulinic acid and low-…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: IL13Rα2 CAR-T Cells Secreting Anti-PD-L1 Antibody for Recurrent Malignant Glioma [Phase 1]
This is a Phase 1 clinical trial evaluating IL13Rα2 CAR-T cells that secrete anti-PD-L1 antibody for recurrent malignant glioma; the study i…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM) [Phase 1, Phase 2]
This clinical trial update covers a Phase 1/2 study evaluating INO-5401 and INO-9012 delivered by electroporation with cemiplimab in newly d…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications [Phase 1, Phase 2]
Clinical trial update for PLX038 in primary CNS tumors with MYC or MYCN amplification; Phase 1/2 studies are currently recruiting.
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies [Phase 1]
Phase 1 clinical trial evaluating RSC-1255 in patients with advanced malignancies carrying RAS mutations, sponsored by RasCal Therapeutics, …
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Coping With Glioblastoma: A Study of Communication Between Physicians, Patients, and Caregivers
This clinical trial update describes a study on communication among physicians, patients, and caregivers in glioblastoma and brain cancer ca…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma [Phase 1]
Phase 1 clinical trial evaluating dual-targeting CAR-NK cells for recurrent or progressive glioblastoma and high-grade glioma is currently r…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Early Phase Study of KESONOTIDE™in Participants With Solid Tumours [Phase 1, Phase 2]
KESONOTIDE is being studied in an early-phase (Phase 1/Phase 2) trial for solid tumours and is currently recruiting across multiple cancer i…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors [Phase 1]
Phase 1 clinical trial evaluating ONC206 for newly diagnosed and recurrent diffuse midline gliomas and other recurrent malignant CNS tumors;…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Daily Temozolomide for Elderly Patients With Unmethylated MGMT- Promoter Newly Diagnosed GliOblatoma [Phase 2]
A Phase 2 clinical trial is testing daily temozolomide in elderly patients with newly diagnosed glioblastoma and unmethylated MGMT promoter;…