Glioblastoma
📧 Sign up to get email alerts when something new happens for Glioblastoma.
Sign up freeTop drugs studied for this disease
-
FDA approval · 2015-04-02FDA Approved: TEMODAR — Supplemental Application (Merck Sharp & Dohme LLC)
The FDA approved a supplemental application for Temodar (temozolomide) from Merck, resulting in an updated labeling and/or indication for th…
-
CLINICAL_TRIALS trial_result · 2015-03-25Clinical Trial Update: Phase II Study of Carmustine, Streptozocin, and Mercaptopurine for Refractory or Recurrent Brain Neoplasms [Phase 2]
A Phase II trial of Carmustine, Streptozocin, and Mercaptopurine for refractory or recurrent brain neoplasms has completed.
-
CLINICAL_TRIALS trial_result · 2015-03-18Clinical Trial Update: Celecoxib in Patients With Newly Diagnosed GBM Who Are Receiving Anticonvulsant Drugs and Undergoing RT [Phase 2]
A Phase 2 trial of celecoxib in newly diagnosed glioblastoma patients receiving anticonvulsants and radiotherapy was terminated, with result…
-
CLINICAL_TRIALS withdrawal · 2015-03-11Clinical Trial Update: A Trial Of PF-04856884 In Patients With Recurrent Glioblastoma [Phase 2]
This document notes a Phase 2 trial of PF-04856884 in recurrent glioblastoma that has been withdrawn.
-
CLINICAL_TRIALS trial_result · 2015-03-09Clinical Trial Update: Safety Study of Replication-competent Adenovirus (Delta-24-rgd) in Patients With Recurrent Glioblastoma [Phase 1, Phase 2]
This is a completed Phase 1/2 safety study of replication-competent adenovirus Delta-24-RGD (DNX-2401) in patients with recurrent glioblasto…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2015-01-07Clinical Trial Update: A Phase I Trial of Nanoliposomal CPT-11 (NL CPT-11) in Patients With Recurrent High-Grade Gliomas [Phase 1]
This report covers a Phase I trial of nanoliposomal irinotecan (NL-CPT-11) in patients with recurrent high-grade gliomas, completed to evalu…
-
CLINICAL_TRIALS trial_result · 2015-01-06Clinical Trial Update: Dasatinib in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma [Phase 2]
Phase 2 trial update evaluating dasatinib in patients with recurrent glioblastoma multiforme or gliosarcoma has completed.
-
CLINICAL_TRIALS trial_result · 2015-01-06Clinical Trial Update: CAR T Cells in Treating Patients With Malignant Gliomas Overexpressing EGFR [Phase 1]
A Phase 1 clinical trial is evaluating CAR T cells targeting EGFR in patients with malignant gliomas, including advanced glioma.
-
CLINICAL_TRIALS trial_result · 2014-12-23Clinical Trial Update: Gamma-Secretase Inhibitor RO4929097 and Cediranib Maleate in Treating Patients With Advanced Solid Tumors [Phase 1]
This Phase 1 trial evaluated the combination of RO4929097, a gamma-secretase inhibitor, with Cediranib maleate in adults with advanced solid…
-
CLINICAL_TRIALS trial_result · 2014-12-23Clinical Trial Update: High-Dose Vorinostat and Fractionated Stereotactic Body Radiation Therapy in Treating Patients With Recurrent Glioma [Phase 1]
Phase 1 trial evaluating high-dose vorinostat with fractionated SBRT in patients with recurrent glioma; the study has been terminated.
-
CLINICAL_TRIALS trial_result · 2014-12-08Clinical Trial Update: Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Unmethylated Gene Promoter Status [Phase 2]
A Phase 2 clinical trial evaluated cilengitide in combination with temozolomide and radiation therapy for newly diagnosed glioblastoma with …
-
CLINICAL_TRIALS trial_result · 2014-12-08Clinical Trial Update: A Study of Bevacizumab and Extended Treatment of Temozolomide in Patients With Recurrent Glioblastoma Multiforme [Phase 2]
Phase 2 trial update assessing bevacizumab with extended temozolomide in patients with recurrent glioblastoma; the study has completed and r…
-
FDA approval · 2014-11-20FDA Approved: GLIADEL — Supplemental Application (Azurity Pharmaceuticals, Inc.)
The FDA approved a supplemental application for GLIADEL (carmustine wafer) from Azurity Pharmaceuticals, Inc., to modify/expand its labeling…
-
CLINICAL_TRIALS trial_result · 2014-11-14Clinical Trial Update: Study of Bevacizumab Plus Temodar and Tarceva in Patients With Glioblastoma or Gliosarcoma [Phase 2]
Phase 2 trial evaluating bevacizumab plus temozolomide (Temodar) and erlotinib (Tarceva) in glioblastoma and gliosarcoma; the study is compl…
-
CLINICAL_TRIALS trial_result · 2014-11-14Clinical Trial Update: Interstitial Infusion of IL13-PE38QQR Cytotoxin in Recurrent Malignant Glioma [Phase 1, Phase 2]
The clinical trial evaluating interstitial infusion of IL13-PE38QQR cytotoxin in recurrent malignant glioma has completed Phase 1 and Phase …
-
CLINICAL_TRIALS trial_result · 2014-11-04Clinical Trial Update: Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Methylated Gene Promoter Status [Phase 3]
Phase 3 trial evaluating cilengitide in combination with temozolomide and radiotherapy for newly diagnosed glioblastoma with MGMT promoter m…
-
CLINICAL_TRIALS trial_result · 2014-11-04Clinical Trial Update: Sorafenib in Newly Diagnosed High Grade Glioma [Phase 1]
Phase 1 trial update evaluating sorafenib in newly diagnosed high-grade glioma, including glioblastoma, gliosarcoma, and various anaplastic …
-
CLINICAL_TRIALS trial_result · 2014-10-30Clinical Trial Update: Immunotherapy for Patients With Brain Stem Glioma and Glioblastoma [Phase 1]
Phase 1 clinical trial investigating an immunotherapy approach for brainstem glioma and glioblastoma has completed.
-
CLINICAL_TRIALS trial_result · 2014-10-13Clinical Trial Update: The Safety and Efficacy of DCA for the Treatment of Brain Cancer [Phase 2]
This Phase 2 trial update reports safety and efficacy data for dichloroacetate (DCA) in treating malignant gliomas, including glioblastoma m…
-
CLINICAL_TRIALS trial_result · 2014-09-22Clinical Trial Update: Safety Study of XL184 (Cabozantinib) in Combination With Temozolomide and Radiation Therapy in the Initial Treatment of Adults With Glioblastoma [Phase 1]
A Phase 1 safety study evaluating cabozantinib (XL184) in combination with temozolomide and radiation for newly diagnosed glioblastoma has c…
-
CLINICAL_TRIALS trial_result · 2014-09-15Clinical Trial Update: Imaging Study of Glioblastomas Treated With Avastin [NA]
This terminated imaging study evaluated glioblastoma patients treated with Avastin (bevacizumab); results were posted in 2014.
-
CLINICAL_TRIALS trial_result · 2014-08-22Clinical Trial Update: Efficacy and Safety of AP 12009 in Patients With Recurrent or Refractory Anaplastic Astrocytoma or Secondary Glioblastoma [Phase 3]
A Phase 3 study of AP-12009 in recurrent or refractory anaplastic astrocytoma or secondary glioblastoma was terminated, and results have bee…
-
CLINICAL_TRIALS trial_result · 2014-08-18Clinical Trial Update: BIBF 1120 for Recurrent High-Grade Gliomas [Phase 2]
Phase 2 trial update on BIBF 1120 (nintedanib) for recurrent high-grade gliomas, with the study status now completed and results posted in 2…
-
CLINICAL_TRIALS trial_result · 2014-08-18Clinical Trial Update: Ph. II Treatment of Adults w Primary Malignant Glioma w Irinotecan + Temozolomide [Phase 2]
Phase II study of irinotecan plus temozolomide in adults with primary malignant glioma, including glioblastoma, has completed.
-
CLINICAL_TRIALS trial_result · 2014-08-15Clinical Trial Update: Comparison of Two Dosing Regimens of Temozolomide in Patients With Progressive or Recurrent Glioblastoma [Phase 2]
Phase 2 trial comparing two dosing regimens of temozolomide in patients with progressive or recurrent glioblastoma.