Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-08-19Clinical Trial Update: Safety Study of AP23573 in Patients With Progressive or Recurrent Glioma (8669-023)(COMPLETED) [Phase 1]
A Phase 1 safety study of ridaforolimus (AP23573) in patients with progressive or recurrent glioma has completed, including glioblastoma and…
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CLINICAL_TRIALS trial_result · 2015-08-07Clinical Trial Update: A Study of Avastin (Bevacizumab) And Fotemustine in Patients With Recurrent Glioblastoma [Phase 2]
Phase 2 trial evaluating bevacizumab (Avastin) with fotemustine in patients with recurrent glioblastoma; results were posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-07-14Clinical Trial Update: RO4929097and Bevacizumab in Treating Patients With Progressive or Recurrent Malignant Glioma [Phase 1, Phase 2]
Phase 1/2 trial evaluating RO4929097 in combination with Bevacizumab for progressive or recurrent malignant glioma was terminated; results w…
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CLINICAL_TRIALS trial_result · 2015-06-16Clinical Trial Update: APG101 in Glioblastoma [Phase 2]
The Phase 2 trial of APG101 in glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2015-06-15Clinical Trial Update: Erlotinib and Temsirolimus in Treating Patients With Recurrent Malignant Glioma [Phase 1, Phase 2]
This entry reports the completion and posted results of a Phase 1/2 trial evaluating erlotinib in combination with temsirolimus for recurren…
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CLINICAL_TRIALS trial_result · 2015-06-12Clinical Trial Update: A Study of PD 0332991 in Patients With Recurrent Rb Positive Glioblastoma [Phase 2]
A Phase 2 study of Palbociclib (PD-0332991) in recurrent RB-positive glioblastoma was terminated. Results were posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-06-11Clinical Trial Update: Phase II NKTR-102 In Bevacizumab-Resistant High Grade Glioma [Phase 2]
A Phase II trial of NKTR-102 in bevacizumab-resistant high-grade glioma has completed, with results posted in 2015, evaluating activity in a…
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CLINICAL_TRIALS withdrawal · 2015-06-11Clinical Trial Update: New Castle Disease Virus (NDV) in Glioblastoma Multiforme (GBM), Sarcoma and Neuroblastoma [Phase 1, Phase 2]
This clinical trial update notes that the Newcastle Disease Virus (NDV) therapy trial for Glioblastoma, Sarcoma, and Neuroblastoma has been …
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FDA approval · 2015-06-10FDA Approved: TEMOZOLOMIDE — Supplemental Application (Sun Pharmaceutical Industries, Inc.)
FDA approves a supplemental application for temozolomide from Sun Pharmaceutical Industries, Inc., under ANDA201742, granting a supplemental…
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2 [Phase 1]
Phase I trial evaluating intratumoral GRm13Z40-2 T-cell therapy (genetically modified allogeneic CD8+ T cells expressing IL-13-Zetakine and …
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CLINICAL_TRIALS trial_result · 2015-06-02Clinical Trial Update: Sorafenib Tosylate and Temsirolimus in Treating Patients With Recurrent Glioblastoma [Phase 1, Phase 2]
Clinical trial evaluating sorafenib tosylate in combination with temsirolimus in adults with recurrent glioblastoma and gliosarcoma has comp…
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FDA approval · 2015-06-01FDA Approved: GLIADEL — Supplemental Application (Azurity Pharmaceuticals, Inc.)
FDA approved a supplemental application for GLIADEL (carmustine) filed by Azurity Pharmaceuticals, Inc.
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CLINICAL_TRIALS withdrawal · 2015-05-22Clinical Trial Update: Valproic Acid in Childhood Progressive Brain Tumors [Phase 1]
The trial withdrawal notice states that the Phase 1 study of valproic acid for childhood progressive brain tumors has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2015-05-12Clinical Trial Update: Re-irradiation of High Grade Gliomas: a Quality of Life Study
A clinical trial studying re-irradiation for high-grade gliomas with a quality-of-life focus has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-05-08Clinical Trial Update: Carboxyamidotriazole + RT in Treating Patients Newly Diagnosed Supratentorial GBM [Phase 2]
Phase 2 trial evaluating carboxyamidotriazole with radiation therapy for newly diagnosed supratentorial glioblastoma and related tumors has …
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CLINICAL_TRIALS trial_result · 2015-05-08Clinical Trial Update: An Observational Pilot Study Evaluating the Feasibility of Conducting Genome-Wide Association Studies Utilizing Subject Provided Information in Subjects With Locally Recurrent or MBC, MCRC, MNSCLC, RGBM or MRCC Treated With Avastin (Bevacizumab) (InVite)
This completed observational pilot trial evaluated the feasibility of conducting genome-wide association studies using subject-provided info…
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CLINICAL_TRIALS trial_result · 2015-05-01Clinical Trial Update: Vandetanib and Sirolimus in Patients With Recurrent Glioblastoma [Phase 1]
Phase 1 study evaluating vandetanib in combination with sirolimus for recurrent glioblastoma has completed enrollment.
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CLINICAL_TRIALS trial_result · 2015-04-29Clinical Trial Update: Radiation Therapy in Treating Patients With Glioblastoma [Phase 1]
A Phase 1 clinical trial evaluating radiation therapy for patients with glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2015-04-28Clinical Trial Update: Cilengitide and Sunitinib Malate in Treating Patients With Advanced Solid Tumors or Glioblastoma Multiforme [Phase 1]
A Phase 1 study evaluating cilengitide in combination with sunitinib malate in adults with advanced solid tumors or glioblastoma multiforme …
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CLINICAL_TRIALS trial_result · 2015-04-22Clinical Trial Update: Super-Selective Intraarterial Intracranial Infusion of Avastin (Bevacizumab) [Phase 1]
Completed Phase 1 study evaluating super-selective intraarterial intracranial infusion of bevacizumab (Avastin) for glioblastoma and anaplas…
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CLINICAL_TRIALS withdrawal · 2015-04-17Clinical Trial Update: Dose-Escalation Study of Carboplatin Administration Into the Brain for Glioblastoma Multiforme [Phase 1]
A phase 1 dose-escalation trial evaluating carboplatin delivered into the brain for glioblastoma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-04-15Clinical Trial Update: Cediranib Maleate and Cilengitide in Treating Patients With Progressive or Recurrent Glioblastoma [Phase 1]
Phase 1 study evaluating the combination of cediranib with cilengitide in adults with progressive or recurrent glioblastoma; the trial has c…
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CLINICAL_TRIALS trial_result · 2015-04-15Clinical Trial Update: Tipifarnib, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma [Phase 1]
Phase 1 trial evaluating the combination of tipifarnib, temozolomide, and radiation therapy in newly diagnosed glioblastoma multiforme or gl…
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CLINICAL_TRIALS trial_result · 2015-04-13Clinical Trial Update: Imaging Biomarkers of Tissue Microstructure and Vasculature as Predictors of Glioblastoma Multiforme
This completed clinical trial evaluated imaging biomarkers of tissue microstructure and vasculature as predictors for glioblastoma.
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CLINICAL_TRIALS trial_result · 2015-04-10Clinical Trial Update: Study With Nelfinavir and Combined Radiochemotherapy for Glioblastoma [Phase 1]
Phase 1 study of Nelfinavir in combination with radiochemotherapy for glioblastoma has completed.