Glioblastoma
📧 Sign up to get email alerts when something new happens for Glioblastoma.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2014-07-21Clinical Trial Update: Ph I SU011248 + Irinotecan in Treatment of Pts w MG [Phase 1]
A Phase I trial evaluating SU011248 in combination with irinotecan for glioblastoma has completed.
-
CLINICAL_TRIALS trial_result · 2014-07-16Clinical Trial Update: Ph I 5-day Temozolomide + O6-BG in Treatment of Pts w Recurrent / Progressive GBM [Phase 1]
A Phase I trial evaluating a 5-day regimen of temozolomide plus O6-benzylguanine in patients with recurrent or progressive glioblastoma and …
-
CLINICAL_TRIALS trial_result · 2014-07-16Clinical Trial Update: Ph I Dasatinib + Erlotinib in Recurrent MG [Phase 1]
Duke University conducted a Phase 1 trial evaluating the combination of dasatinib and erlotinib in recurrent malignant glioma, including gli…
-
CLINICAL_TRIALS trial_result · 2014-07-02Clinical Trial Update: Early Detection of Glioblastoma Multiforme (GBM) Treatment Responses Using Multiple Magnetic Resonance Modalities
This terminated clinical trial evaluated using multiple magnetic resonance imaging modalities to detect early treatment responses in gliobla…
-
CLINICAL_TRIALS trial_result · 2014-06-11Clinical Trial Update: Magnetic Resonance Spectroscopy Imaging in Predicting Response to Vorinostat and Temozolomide in Patients With Recurrent or Progressive Glioblastoma [NA]
A completed clinical trial evaluating magnetic resonance spectroscopy imaging to predict response to vorinostat and temozolomide in recurren…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2014-06-09Clinical Trial Update: Reproducibility of 18F Uptake by Solid Tumors Using PET Imaging Following Intravenous Administration of (18F) Injection [Phase 2]
Phase 2 clinical trial evaluating the reproducibility of 18F uptake in solid tumors using PET imaging after intravenous administration of a …
-
CLINICAL_TRIALS withdrawal · 2014-06-02Clinical Trial Update: Genetically Modified Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas [Phase 1]
Phase 1 trial evaluating genetically modified stem cells with Irinotecan hydrochloride for recurrent high-grade gliomas has been withdrawn.
-
CLINICAL_TRIALS trial_result · 2014-05-30Clinical Trial Update: Aflibercept, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma Multiforme, Gliosarcoma, or Other Malignant Glioma [Phase 1]
Phase 1 clinical trial assessing aflibercept in combination with radiation therapy and temozolomide in adults with newly diagnosed or recurr…
-
CLINICAL_TRIALS trial_result · 2014-05-30Clinical Trial Update: Sorafenib in Treating Patients With Recurrent or Progressive Malignant Glioma [Phase 1]
This update covers a Phase 1 trial of sorafenib in patients with recurrent or progressive malignant glioma, including several glioma subtype…
-
CLINICAL_TRIALS withdrawal · 2014-05-19Clinical Trial Update: Effects of Steroid Tapering on Functional Capacity and Neurocognition [NA]
Duke University-sponsored trial evaluating steroid tapering effects on functional capacity and neurocognition in glioblastoma patients has b…
-
CLINICAL_TRIALS trial_result · 2014-05-19Clinical Trial Update: Peptide-based Glioma Vaccine IMA950 in Patients With Glioblastoma [Phase 1]
A Phase 1 study evaluating the peptide-based glioma vaccine IMA950 in patients with glioblastoma has been terminated.
-
CLINICAL_TRIALS trial_result · 2014-05-15Clinical Trial Update: A Phase 1 / 2 Dose Escalation Study of Locally-Administered OncoGel™ in Subjects With Recurrent Glioma [Phase 1, Phase 2]
Phase 1/2 dose-escalation study of Locally-Administered OncoGel in recurrent glioma was terminated; results posted in 2014.
-
CLINICAL_TRIALS trial_result · 2014-05-12Clinical Trial Update: TRC105 for Recurrent Glioblastoma [Phase 2]
Phase 2 trial of TRC105 for recurrent glioblastoma was terminated; results were posted in 2014.
-
CLINICAL_TRIALS trial_result · 2014-04-30Clinical Trial Update: Radiation Therapy (RT) and Temozolomide (TMZ) in Treating Patients With Newly Diagnosed Glioblastoma or Gliosarcoma [Phase 3]
A Phase 3 trial evaluating radiation therapy with temozolomide for newly diagnosed glioblastoma or gliosarcoma has completed with results po…
-
CLINICAL_TRIALS trial_result · 2014-04-24Clinical Trial Update: Dose Confirmation Study of Cotara for the Treatment of Glioblastoma Multiforme at First Relapse [Phase 2]
Phase 2 dose confirmation study of Cotara for glioblastoma at first relapse has completed.
-
CLINICAL_TRIALS trial_result · 2014-04-17Clinical Trial Update: Epothilone in Recurrent Glioblastoma Patients [Phase 2]
Phase 2 trial update for epothilone in recurrent glioblastoma has completed.
-
CLINICAL_TRIALS trial_result · 2014-03-14Clinical Trial Update: Dose-Intense Temozolomide in Recurrent Glioblastoma [Phase 2]
Phase 2 trial assessing a dose-intensive temozolomide regimen in patients with recurrent glioblastoma and gliosarcoma; results were posted i…
-
CLINICAL_TRIALS trial_result · 2014-03-04Clinical Trial Update: A Study of the Safety and Efficacy of Tarceva in Patients With First Relapse of Grade IV Glioma (Glioblastoma Multiforme) [Phase 2]
A Phase 2 study evaluating Tarceva (erlotinib) for safety and efficacy in patients with first relapse glioblastoma; the trial has been compl…
-
CLINICAL_TRIALS trial_result · 2014-02-20Clinical Trial Update: Cilengitide in Treating Younger Patients With Recurrent or Progressive High-Grade Glioma That Has Not Responded to Standard Therapy [Phase 2]
This Phase 2, NCI-sponsored trial evaluated cilengitide in children and adolescents with recurrent or progressive high-grade glioma refracto…
-
CLINICAL_TRIALS trial_result · 2014-02-19Clinical Trial Update: Bevacizumab and Cediranib Maleate in Treating Patients With Metastatic or Unresectable Solid Tumor, Lymphoma, Intracranial Glioblastoma, Gliosarcoma or Anaplastic Astrocytoma [Phase 1]
Phase 1 study evaluating the safety and potential activity of bevacizumab plus cediranib in patients with metastatic or unresectable solid t…
-
FDA approval · 2014-02-12FDA Approved: TEMOZOLOMIDE — Original Application (Sun Pharmaceutical Industries, Inc.)
FDA approved a generic temozolomide product under an original ANDA from Sun Pharmaceutical Industries, Inc. Temozolomide is used to treat ma…
-
CLINICAL_TRIALS trial_result · 2014-02-04Clinical Trial Update: Phase II Avastin + Bortezomib for Patients With Recurrent Malignant Glioma [Phase 2]
A Phase II study evaluating bevacizumab (Avastin) with bortezomib for recurrent malignant glioma has completed and posted results, involving…
-
CLINICAL_TRIALS trial_result · 2014-02-04Clinical Trial Update: Cilengitide Imaging Trial in Glioblastoma [Phase 1]
Phase 1 imaging trial of cilengitide in supratentorial newly diagnosed inoperable glioblastoma has been terminated.
-
CLINICAL_TRIALS trial_result · 2014-01-28Clinical Trial Update: Treatment Response and Prognosis in Glioma Patients: Q Cell and Its Biological Characteristics
An update on a clinical trial evaluating Q Cell in glioma patients, focusing on treatment response and prognosis.
-
CLINICAL_TRIALS withdrawal · 2014-01-14Clinical Trial Update: Peptide Vaccine for Glioblastoma Against Cytomegalovirus Antigens [Phase 1]
A Phase 1 trial of a cytomegalovirus antigen–targeted peptide vaccine for glioblastoma has been withdrawn.