Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2018-06-07Clinical Trial Update: Early-Phase Study to Assess Inhibitor Ribociclib in Patients With Recurrent Glioblastoma or Anaplastic Glioma [Phase 1]
Phase 1 clinical trial update evaluating the CDK4/6 inhibitor ribociclib in patients with recurrent glioblastoma or anaplastic glioma.
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CLINICAL_TRIALS trial_result · 2018-05-24Clinical Trial Update: Safety and Efficacy of INC280 and Buparlisib (BKM120) in Patients With Recurrent Glioblastoma [Phase 1, Phase 2]
This clinical trial update reports the safety and preliminary efficacy results from a Phase 1/2 study of INC280 (capmatinib) and buparlisib …
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CLINICAL_TRIALS trial_result · 2018-05-23Clinical Trial Update: Bevacizumab With or Without Anti-Endoglin Monoclonal Antibody TRC105 in Treating Patients With Recurrent Glioblastoma Multiforme [Phase 1, Phase 2]
This clinical trial assessed bevacizumab with or without the anti-endoglin monoclonal antibody TRC105 in patients with recurrent glioblastom…
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CLINICAL_TRIALS trial_result · 2018-05-21Clinical Trial Update: A Study of a Retroviral Replicating Vector Combined With a Prodrug Administered to Patients With Recurrent Malignant Glioma [Phase 1]
Phase 1 study evaluating the safety and feasibility of Toca 511, a retroviral replicating vector, in combination with the prodrug Toca FC in…
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CLINICAL_TRIALS research · 2018-05-11Clinical Trial Update: BIRN (Biomedical Informatics Research Network) Resources Facilitate the Personalization of Malignant Brain Tumor
This clinical trial update discusses how BIRN resources support personalizing treatment for malignant brain tumors, including glioblastoma. …
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CLINICAL_TRIALS trial_result · 2018-05-03Clinical Trial Update: A Randomised Trial Investigating the Additional Benefit of Hydroxychloroquine(HCQ)to Short Course Radiotherapy (SCRT) in Patients Aged 70 Years and Older With High Grade Gliomas (HGG) [Phase 2]
A Phase 2 randomized trial evaluated the potential benefit of adding hydroxychloroquine to short-course radiotherapy in patients aged 70 and…
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CLINICAL_TRIALS trial_result · 2018-04-30Clinical Trial Update: A Comparison of Continuous Bevacizumab (Avastin) Treatment or Placebo in Addition to Lomustine Followed by Standard of Care After Disease Progression in Participants With Glioblastoma [Phase 2]
This Phase 2 study compares continuous bevacizumab (Avastin) versus placebo, in addition to lomustine, for glioblastoma after progression. T…
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CLINICAL_TRIALS trial_result · 2018-04-25Clinical Trial Update: Prevention of Thrombocytopenia in Glioblastoma Patients [Phase 2]
A Phase 2 clinical trial assessing strategies to prevent thrombocytopenia in glioblastoma patients has been terminated.
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CLINICAL_TRIALS trial_result · 2018-04-18Clinical Trial Update: qBOLD MRI of Glioblastoma Multiforme for Assessment of Tumor Hypoxia. [EARLY_Phase 1]
This clinical trial update reports the completion of an early Phase 1 study using qBOLD MRI to assess tumor hypoxia in glioblastoma. The tri…
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CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: Bafetinib in Treating Patients With Recurrent High-Grade Glioma or Brain Metastases [Phase 1]
This Phase 1 trial assessing bafetinib in adults with recurrent high-grade glioma or brain metastases has completed.
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CLINICAL_TRIALS trial_result · 2018-04-13Clinical Trial Update: A Study of Subcutaneous Bevacizumab in Relapsed / Progressive Glioblastoma [Phase 2]
Phase 2 study evaluating subcutaneous bevacizumab for relapsed or progressive glioblastoma; results were posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-04-09Clinical Trial Update: Pembrolizumab +/- Bevacizumab for Recurrent GBM [Phase 2]
Phase 2 trial updating pembrolizumab with or without bevacizumab in recurrent glioblastoma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-04-04Clinical Trial Update: Derivation of Tumor Specific Hybridomas [Phase 1]
A Phase 1 clinical trial at Dartmouth-Hitchcock Medical Center investigating derivation of tumor-specific hybridomas for glioblastoma has be…
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CLINICAL_TRIALS trial_result · 2018-04-02Clinical Trial Update: Trial of Ponatinib in Patients With Bevacizumab-Refractory Glioblastoma [Phase 2]
Phase 2 trial of ponatinib in bevacizumab-refractory glioblastoma has completed and results were posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-04-02Clinical Trial Update: Perampanel in Seizure Patients With Primary Glial Brain Tumors [Phase 4]
Phase 4 study of perampanel for seizures in patients with primary glial brain tumors completed; results were posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-03-30Clinical Trial Update: A Study Evaluating Safety and Pharmacokinetics of ABBV-221 in Subjects With Advanced Solid Tumor Types Likely to Exhibit Elevated Levels of Epidermal Growth Factor Receptor [Phase 1]
A Phase 1 trial evaluating the safety and pharmacokinetics of ABBV-221 in adults with advanced solid tumors likely to overexpress EGFR was t…
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CLINICAL_TRIALS trial_result · 2018-03-22Clinical Trial Update: Study of Induction of Hypothyroxinemia Adjunct to Conventional Therapies in GBM Patients [Phase 2]
A phase 2 trial investigating induction of hypothyroxinemia as an adjunct to standard therapies in glioblastoma has been terminated.
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CLINICAL_TRIALS trial_result · 2018-03-07Clinical Trial Update: Temozolomide & RT Followed by Dose Dense vs Temozolomide & Retinoic Acid in Pts w/Glioblastoma [Phase 2]
Phase 2 trial in glioblastoma comparing dose-dense temozolomide after chemoradiation to temozolomide with all-trans retinoic acid; results p…
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CLINICAL_TRIALS trial_result · 2018-02-28Clinical Trial Update: An Observational Study of Avastin (Bevacizumab) in Patients With Glioblastoma Multiforme in First or Second Relapse
An observational study of bevacizumab (Avastin) in patients with glioblastoma at first or second relapse has completed.
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CLINICAL_TRIALS trial_result · 2018-02-27Clinical Trial Update: Clinical Study on Macitentan, RT and TMZ Concurrent Therapy Followed by Maintenance Macitentan and TMZ in Newly Diagnosed Glioblastoma [Phase 1]
Phase 1 trial evaluating concurrent macitentan with radiotherapy and temozolomide followed by maintenance macitentan and temozolomide in new…
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CLINICAL_TRIALS trial_result · 2018-02-23Clinical Trial Update: A Study on β-elemene as Maintain Treatment for Newly Diagnosed Malignant Gliomas [Phase 3]
Phase 3 trial update on β-elemene as maintenance therapy for newly diagnosed malignant gliomas is ongoing, status currently unknown.
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CLINICAL_TRIALS trial_result · 2018-02-23Clinical Trial Update: Temozolomide and Ascorbic Acid in Treating Patients With Recurrent High-Grade Glioma [Phase 1]
A Phase 1 trial evaluating temozolomide with ascorbic acid in recurrent high-grade glioma was terminated; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-02-23Clinical Trial Update: A Phase III Trial on Adjuvant Temozolomide With or Without Interferon-alpha in Newly Diagnosed High-grade Gliomas [Phase 3]
Phase III trial investigating adjuvant temozolomide with or without interferon-alpha in newly diagnosed high-grade gliomas, including anapla…
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CLINICAL_TRIALS trial_result · 2018-02-05Clinical Trial Update: A Study of Onartuzumab (MetMAb) in Combination With Bevacizumab Compared to Bevacizumab Alone or Onartuzumab Monotherapy in Participants With Recurrent Glioblastoma [Phase 2]
Phase 2 trial evaluating Onartuzumab with bevacizumab versus bevacizumab alone or onartuzumab alone in recurrent glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2018-01-16Clinical Trial Update: Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma [Phase 3]
Phase III trial of rindopepimut/GM-CSF in newly diagnosed glioblastoma has completed.