Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-01-03Clinical Trial Update: Nimotuzumab Plus Radiotherapy With Concomitant and Adjuvant Temozolomide for Cerebral Glioblastoma [Phase 2]
Phase 2 trial evaluating nimotuzumab with radiotherapy and temozolomide for glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2017-12-13Clinical Trial Update: Antineoplaston Therapy in Treating Patients With Newly-diagnosed Glioblastoma Multiforme [Phase 2]
Phase 2 clinical trial of antineoplaston therapy for newly diagnosed glioblastoma has completed, with results posted.
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CLINICAL_TRIALS research · 2017-12-13Clinical Trial Update: FET-PET and Multiparametric MRI for High-grade Glioma Patients Undergoing Radiotherapy
A clinical trial update from University Hospital, Brest describes evaluating FET-PET imaging and multiparametric MRI to guide radiotherapy i…
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CLINICAL_TRIALS research · 2017-12-11Clinical Trial Update: PET/CT Evaluation of Primary and Metastatic Brain Tumors With a Novel Radioiodinated Phospholipid Ether Analogue I-NM404 [NA]
Clinical trial evaluating PET/CT imaging using I-NM404 for glioblastoma multiforme and brain metastases; study completed with results posted…
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CLINICAL_TRIALS trial_result · 2017-12-06Clinical Trial Update: Molecular Profiling in Guiding Individualized Treatment Plan in Adults With Recurrent/Progressive Glioblastoma
Clinical trial on molecular profiling to guide individualized treatment in adults with recurrent/progressive glioblastoma has completed and …
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CLINICAL_TRIALS trial_result · 2017-12-02Clinical Trial Update: Vaccination With Dendritic Cells Loaded With Brain Tumor Stem Cells for Progressive Malignant Brain Tumor [Phase 1]
Phase 1 trial evaluating autologous dendritic cells loaded with brain tumor stem cells for progressive malignant brain tumors has completed.
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CLINICAL_TRIALS trial_result · 2017-11-21Clinical Trial Update: Evaluating the Safety and Pharmacokinetics of ABT-414 for Subjects With Glioblastoma Multiforme [Phase 1]
Phase 1 clinical trial results evaluating the safety and pharmacokinetics of ABT-414 in patients with glioblastoma.
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: Plerixafor (AMD3100) and Bevacizumab for Recurrent High-Grade Glioma [Phase 1]
Phase 1 trial evaluating the combination of plerixafor (AMD3100) and bevacizumab for recurrent high-grade glioma has been terminated. The st…
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: Research for Immunotherapy of Glioblastoma With Autologous Heat Shock Protein gp96 [Phase 1]
A Phase 1 trial evaluating an autologous heat shock protein gp96 vaccine for glioblastoma/glioma has completed.
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: Neoepitope-based Personalized Vaccine Approach in Patients With Newly Diagnosed Glioblastoma [Phase 1]
The Phase 1 trial of a neoepitope-based personalized vaccine for newly diagnosed glioblastoma was terminated.
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CLINICAL_TRIALS trial_result · 2017-11-09Clinical Trial Update: A Pilot Feasibility Study of Oral 5-Fluorocytosine and Genetically-Modified Neural Stem Cells Expressing E.Coli Cytosine Deaminase for Treatment of Recurrent High Grade Gliomas [Phase 1]
Phase 1 feasibility trial evaluating oral 5-fluorocytosine in combination with genetically modified neural stem cells expressing E. coli cyt…
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CLINICAL_TRIALS trial_result · 2017-11-06Clinical Trial Update: Safety and Efficacy of the ONCOlytic VIRus Armed for Local Chemotherapy, TG6002/5-FC, in Recurrent Glioblastoma Patients [Phase 1, Phase 2]
Clinical trial update reports on the safety and efficacy of the ONCOlytic virus TG6002 with its prodrug 5-FC in recurrent glioblastoma, span…
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CLINICAL_TRIALS trial_result · 2017-10-26Clinical Trial Update: Prospective Phase 2 Trial of Cabazitaxel in Patients With Temozolomide Refractory Glioblastoma Multiforme [Phase 2]
A prospective Phase 2 trial of cabazitaxel in temozolomide-refractory glioblastoma multiforme has completed.
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CLINICAL_TRIALS trial_result · 2017-10-25Clinical Trial Update: Using Genomic Analysis to Guide Individual Treatment in Glioblastoma
A completed Rockefeller University clinical trial investigates using tumor genomic analysis to guide individualized treatment for glioblasto…
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CLINICAL_TRIALS research · 2017-10-25Clinical Trial Update: Retrospective Evaluation of Melanocortin Receptor 4 Polymorphisms in Patients With GBM Treated With Radiochemotherapy
This study retrospectively examined melanocortin-4 receptor polymorphisms in glioblastoma patients treated with radiochemotherapy.
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CLINICAL_TRIALS trial_result · 2017-10-24Clinical Trial Update: Metabolic Tumor Volumes in Radiation Treatment of Primary Brain Tumors
Update on a University of Miami trial evaluating metabolic tumor volumes during radiation therapy for glioblastoma, with the study status sh…
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CLINICAL_TRIALS trial_result · 2017-10-24Clinical Trial Update: Virus DNX2401 and Temozolomide in Recurrent Glioblastoma [Phase 1]
Clinical trial update reporting on a Phase 1 study of DNX-2401 in combination with temozolomide for recurrent glioblastoma.
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CLINICAL_TRIALS other · 2017-10-18Clinical Trial Update: Expanded Access (Compassionate Use) Treatment Protocol Rindopepimut
Expanded access/compassionate use protocol for rindopepimut in recurrent glioblastoma has ended or is no longer available.
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CLINICAL_TRIALS trial_result · 2017-10-17Clinical Trial Update: Concomitant Association of Ultrafractionated Brain Irradiation - Temozolomide in Inoperable Primary Glioblastoma Multiforme [Phase 2]
A Phase 2 trial evaluating concomitant ultrfractionated brain irradiation with temozolomide for inoperable primary glioblastoma multiforme h…
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CLINICAL_TRIALS trial_result · 2017-10-13Clinical Trial Update: MET-PET for Newly Diagnosed Glioblastoma [EARLY_Phase 1]
A MET-PET imaging study for newly diagnosed Glioblastoma has completed its EARLY Phase 1 trial.
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CLINICAL_TRIALS research · 2017-10-12Clinical Trial Update: Image-derived Prediction of Response to Chemo-radiation in Glioblastoma
Clinical trial update indicating termination of a study evaluating image-derived prediction of response to chemo-radiation in glioblastoma.
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CLINICAL_TRIALS research · 2017-10-12Clinical Trial Update: Proteome-based Personalized Immunotherapy of Glioblastoma [Phase 2, Phase 3]
This document notes an ongoing Phase 2/Phase 3 trial of proteome-based personalized immunotherapy for glioblastoma, with the current status …
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CLINICAL_TRIALS trial_result · 2017-10-09Clinical Trial Update: Cellular Adoptive Immunotherapy Using Genetically Modified T-Lymphocytes in Treating Patients With Recurrent or Refractory High-Grade Malignant Glioma [Phase 1]
Phase 1 trial assessing adoptive immunotherapy with genetically modified T-lymphocytes for recurrent or refractory high-grade malignant glio…
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FDA approval · 2017-09-14FDA Approved: MVASI — Original Application (Amgen, Inc)
The FDA approved MVASI (bevacizumab-awwb) from Amgen as a biosimilar to Avastin, marking the original application granting U.S. approval for…
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CLINICAL_TRIALS trial_result · 2017-08-18Clinical Trial Update: Efficacy and Safety of Atorvastatin in Combination With Radiotherapy and Temozolomide in Glioblastoma [Phase 2]
Phase 2 study evaluating the efficacy and safety of adding atorvastatin to radiotherapy and temozolomide in glioblastoma; trial completed.