Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-01-24Clinical Trial Update: A Randomized Phase II Clinical Trial on the Efficacy of Axitinib as a Monotherapy or in Combination With Lomustine for the Treatment of Patients With Recurrent Glioblastoma [Phase 2]
A randomized Phase II study evaluated axitinib as a monotherapy or in combination with lomustine for recurrent glioblastoma; the trial has c…
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CLINICAL_TRIALS trial_result · 2019-01-23Clinical Trial Update: Clinical Trial on the Combination of Avelumab and Axitinib for the Treatment of Patients With Recurrent Glioblastoma [Phase 2]
This update reports the completion of a Phase 2 trial evaluating the combination of Bavencio (avelumab) and Inlyta (axitinib) in patients wi…
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CLINICAL_TRIALS research · 2019-01-17Clinical Trial Update: Study of Tissue and Blood Samples From Patients With High-Grade Glioma
A completed clinical trial update describing the collection of tissue and blood samples from patients with high-grade glioma to study biolog…
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CLINICAL_TRIALS trial_result · 2019-01-08Clinical Trial Update: Tivozanib for Recurrent Glioblastoma [Phase 2]
Phase 2 clinical trial update for tivozanib in recurrent glioblastoma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-12-28Clinical Trial Update: O6-Benzylguanine-Mediated Tumor Sensitization With Chemoprotected Autologous Stem Cell in Treating Patients With Malignant Gliomas [Phase 1, Phase 2]
Early-phase trial investigating O6-Benzylguanine–mediated tumor sensitization with chemoprotected autologous stem cell therapy in malignant …
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CLINICAL_TRIALS trial_result · 2018-11-19Clinical Trial Update: To Evaluate the Efficacy and Safety of CAN008 Combined With Re-irradiation (rRT) for Treating Patients With Recurrent Glioblastoma (GBM) [Phase 2]
Phase 2 trial evaluating CAN008 combined with re-irradiation for recurrent glioblastoma; results not yet specified.
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CLINICAL_TRIALS trial_result · 2018-10-23Clinical Trial Update: A Phase 3, Pivotal Trial of VB-111 Plus Bevacizumab vs. Bevacizumab in Patients With Recurrent Glioblastoma (GLOBE) [Phase 3]
Phase 3 pivotal trial comparing VB-111 plus bevacizumab versus bevacizumab in recurrent glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2018-10-12Clinical Trial Update: Safety of BBB Opening With the SonoCloud [Phase 1, Phase 2]
Phase 1/2 trial update on safety of SonoCloud-induced BBB opening for glioblastoma and glioma patients; study completed.
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CLINICAL_TRIALS trial_result · 2018-09-28Clinical Trial Update: PVSRIPO for Recurrent Glioblastoma (GBM) [Phase 1]
Phase 1 clinical trial update for PVSRIPO in recurrent glioblastoma (GBM) completed with results posted in 2018.
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FDA approval · 2018-08-22FDA Approved: GLEOLAN — Supplemental Application (Medexus Pharma, Inc.)
FDA approved a supplemental application for Gleolan (aminolevulinic acid hydrochloride) submitted by Medexus Pharma, Inc. This action consti…
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CLINICAL_TRIALS trial_result · 2018-08-16Clinical Trial Update: Efficacy of Two Temozolomide Regimens in Adjuvant Treatment of Patients With Brain High Grade Glioma [Phase 3]
A Phase 3 clinical trial comparing two temozolomide regimens for adjuvant treatment in high-grade glioma of the brain, including glioblastom…
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CLINICAL_TRIALS trial_result · 2018-08-16Clinical Trial Update: PF-00299804 in Adult Patients With Relapsed/Recurrent Glioblastoma [Phase 2]
Phase 2 trial update for PF-00299804 in adults with relapsed/recurrent glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2018-07-31Clinical Trial Update: Bevacizumab and Nimustine in Patients With Recurrent High Grade Glioma [Phase 2]
A Phase 2 clinical trial update on bevacizumab plus nimustine for patients with recurrent glioblastoma. The study has completed.
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CLINICAL_TRIALS trial_result · 2018-07-31Clinical Trial Update: A Study of the Efficacy of Cannabidiol in Patients With Multiple Myeloma, Glioblastoma Multiforme, and GI Malignancies [Phase 1, Phase 2]
A Phase 1/2 clinical trial is investigating cannabidiol for efficacy in multiple myeloma, glioblastoma, and various gastrointestinal cancers…
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CLINICAL_TRIALS trial_result · 2018-07-20Clinical Trial Update: Disulfiram in Treating Patients With Glioblastoma Multiforme After Radiation Therapy With Temozolomide [EARLY_Phase 1]
A Phase 1 study update evaluating disulfiram for glioblastoma following standard therapy with radiation and temozolomide; the study status i…
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CLINICAL_TRIALS withdrawal · 2018-07-20Clinical Trial Update: Fluorescein vs. iMRI in Resection of Malignant High Grade Glioma [NA]
The clinical trial NCT02540135 evaluating fluorescein-guided resection with intraoperative MRI for malignant high-grade gliomas has been wit…
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CLINICAL_TRIALS withdrawal · 2018-07-19Clinical Trial Update: Clinical Trial of the Use of the Nasal Spray of Patients With Recurrence of Glioblastoma [Phase 1]
A Phase 1 clinical trial evaluating a nasal spray for recurrent glioblastoma and related gliomas has been withdrawn.
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CLINICAL_TRIALS trial_result · 2018-07-16Clinical Trial Update: DNX-2401 With Interferon Gamma (IFN-γ) for Recurrent Glioblastoma or Gliosarcoma Brain Tumors [Phase 1]
A Phase 1 trial evaluating DNX-2401 in combination with interferon gamma for recurrent glioblastoma or gliosarcoma has completed.
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CLINICAL_TRIALS trial_result · 2018-07-09Clinical Trial Update: Pharmacokinetics in Patients With Newly Diagnosed High-Grade Glioma Receiving Temozolomide and Radiation Therapy
This clinical trial update reports pharmacokinetic data from a study of temozolomide with radiation therapy in patients with newly diagnosed…
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CLINICAL_TRIALS trial_result · 2018-07-09Clinical Trial Update: Radiation Therapy and Temsirolimus or Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma [Phase 2]
This clinical trial update reports a Phase 2 study evaluating radiation therapy with temsirolimus or temozolomide for newly diagnosed gliobl…
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: (11C)dLop as a Marker of P-Glycoprotein Function in Patients With Gliomas
A clinical trial evaluating the PET tracer 11C-dLop as a marker of P-glycoprotein function in gliomas was terminated. The study enrolled pat…
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CLINICAL_TRIALS trial_result · 2018-07-03Clinical Trial Update: Plerixafor After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed High Grade Glioma [Phase 1, Phase 2]
Phase 1/2 clinical trial assessing plerixafor after radiation therapy and temozolomide in newly diagnosed high-grade glioma has completed wi…
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CLINICAL_TRIALS trial_result · 2018-07-03Clinical Trial Update: Radiosurgery Plus Bevacizumab in Glioblastoma [EARLY_Phase 1]
This clinical trial update reports the termination of an early Phase 1 study evaluating radiosurgery in combination with bevacizumab for gli…
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CLINICAL_TRIALS trial_result · 2018-07-03Clinical Trial Update: Yoga Therapy in Treating Patients With Malignant Brain Tumors [NA]
This entry notes a terminated clinical trial at Wake Forest evaluating yoga therapy for adults with malignant brain tumors.
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FDA approval · 2018-06-12FDA Approved: GLEOLAN — Supplemental Application (Medexus Pharma, Inc.)
FDA approved a supplemental application for Gleolan (aminolevulinic acid hydrochloride) submitted by Medexus Pharma, Inc.