Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-07-26Clinical Trial Update: A Study of CC-90010 in Combination With Temozolomide With or Without Radiation Therapy in Participants With Newly Diagnosed Glioblastoma [Phase 1]
This update indicates the Phase 1 study of CC-90010 in combination with temozolomide, with or without radiation therapy, for newly diagnosed…
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CLINICAL_TRIALS trial_result · 2024-07-26Clinical Trial Update: A Study of Sonodynamic Therapy Using SONALA-001 and Exablate 4000 Type 2.0 in Subjects With Recurrent GBM [Phase 1, Phase 2]
This terminated Phase 1/2 trial evaluated sonodynamic therapy using SONALA-001 in combination with the Exablate 4000 Type 2.0 device for rec…
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CLINICAL_TRIALS trial_result · 2024-07-24Clinical Trial Update: Cytokine Microdialysis for Real-Time Immune Monitoring in Glioblastoma Patients Undergoing Checkpoint Blockade [Phase 1]
This Phase 1 trial investigates cytokine microdialysis for real-time immune monitoring in glioblastoma patients undergoing checkpoint blocka…
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CLINICAL_TRIALS research · 2024-07-24Clinical Trial Update: Research on the Safety and Efficacy of Blocking Dural Blood Supply in Glioblastoma Patients [NA]
This clinical trial update describes research evaluating blocking the dural blood supply in glioblastoma patients to assess safety and effic…
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CLINICAL_TRIALS trial_result · 2024-07-19Clinical Trial Update: Evaluating Therapeutic Response to Novo-TTF [NA]
This clinical trial update reports the completion of a trial evaluating therapeutic response to Novo-TTF therapy in glioblastoma.
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CLINICAL_TRIALS withdrawal · 2024-07-16Clinical Trial Update: Single Patient Compassionate Use / Expanded Access L-S-Gboxin (Lyophilized Form of S-Gboxin) for the Treatment of Diffuse Midline Glioma
Single-patient compassionate-use/expanded-access study of L-S-Gboxin for diffuse midline glioma is no longer available.
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CLINICAL_TRIALS research · 2024-07-08Clinical Trial Update: Expectations and Needs of a Glioblastoma Caregiver
A completed study investigating the expectations and needs of caregivers for patients with glioblastoma.
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas [Phase 1, Phase 2]
A Phase I/Phase II study evaluating mebendazole for pediatric gliomas has completed. It enrolled children with various glial tumors, includi…
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: CNS Penetration, PK and PD of Preoperative CC-90010 in Progressive/Recurrent Diffuse Astrocytoma, Anaplastic Astrocytoma and Glioblastoma [Phase 1]
Phase 1 study of CC-90010 assesses CNS penetration, pharmacokinetics, and pharmacodynamics in progressive/recurrent diffuse astrocytoma, ana…
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Tumor Treating Fields for Newly Diagnosed Glioblastoma: Two Emulated Trials With Chinese Multi-Hospital Based Real-World Data
Two emulated real-world trials using multi-hospital Chinese data evaluated Tumor Treating Fields for newly diagnosed glioblastoma; the study…
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Multimodal MR Imaging in Patients With Glioblastoma Treated With Dendritic Cell Therapy
This clinical trial update reports on multimodal MRI imaging findings in glioblastoma patients treated with dendritic cell therapy.
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CLINICAL_TRIALS trial_result · 2024-07-01Clinical Trial Update: A Study of PRT3645 in Participants With Select Advanced or Metastatic Solid Tumors [Phase 1]
A Phase 1 study of PRT3645 conducted by Prelude Therapeutics in patients with several advanced solid tumors has completed, including breast …
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CLINICAL_TRIALS research · 2024-06-28Clinical Trial Update: FET-PET-Guided Management of Pseudoprogression in Glioblastoma [NA]
A clinical trial studying FET-PET-guided management of pseudoprogression in glioblastoma, with recruitment not yet started.
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CLINICAL_TRIALS research · 2024-06-27Clinical Trial Update: Study of Adding or Not Liposomal Transcrocetin (L-TC) With Concomitant HypoFractionated Radiation ThErapy and TEmozolomide in Newly Diagnosed GLioblastoma (GBM) Patients [Phase 3]
A Phase 3 trial is planned to evaluate adding liposomal transcrocetin to hypofractionated radiotherapy and temozolomide in newly diagnosed g…
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: Whole Brain Radiation Therapy With Standard Temozolomide Chemo-Radiotherapy and Plerixafor in Treating Patients With Glioblastoma [Phase 2]
A Phase 2 clinical trial assessing the addition of plerixafor to standard temozolomide-based chemoradiotherapy for glioblastoma has complete…
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: Phase 1/2a Study of Oral BAL101553 in Adult Patients With Solid Tumors or Glioblastoma or High-grade Glioma [Phase 1, Phase 2]
This ClinicalTrials.gov update reports that results for the Phase 1/2a trial of oral BAL101553 in adults with solid tumors, glioblastoma, an…
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CLINICAL_TRIALS trial_result · 2024-06-25Clinical Trial Update: The PCSK9i Inhibitor Evolocumab - a Surgical Trial of Pharamcodynamics and Kinetics Evaluation [EARLY_Phase 1]
An early-phase 1 clinical trial evaluating the pharmacodynamics and pharmacokinetics of evolocumab (a PCSK9 inhibitor) in patients with mali…
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CLINICAL_TRIALS trial_result · 2024-06-24Clinical Trial Update: Microtubule-Targeted Agent BAL101553 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma [Phase 1]
A Phase 1 trial evaluating BAL101553 in combination with radiation for newly diagnosed glioblastoma was terminated, with results posted in 2…
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CLINICAL_TRIALS research · 2024-06-24Clinical Trial Update: Preoperative Preradiotherapy TTFields [NA]
Clinical trial update on preoperative preradiotherapy Tumor Treating Fields (TTFields) for Glioblastoma. The study is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2024-06-17Clinical Trial Update: 18F-FluorThanatrace (PET/CT) in Glioblastoma [EARLY_Phase 1]
An early-phase 1 trial evaluating 18F-FluorThanatrace PET/CT in glioblastoma has been terminated.
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CLINICAL_TRIALS research · 2024-06-06Clinical Trial Update: MRI Hypoxia Study for Glioblastoma Multiforme (GBM) Radiation Therapy
A clinical trial update for an MRI hypoxia imaging study in glioblastoma patients undergoing radiation therapy, sponsored by the University …
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CLINICAL_TRIALS trial_result · 2024-06-05Clinical Trial Update: Sintilimab in Combination With Bevacizumab and Temozolomide in Recurrent Glioblastoma (GBM) Patients [Phase 2]
Phase 2 clinical trial evaluating the combination of sintilimab, bevacizumab, and temozolomide for recurrent glioblastoma; status details ar…
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CLINICAL_TRIALS trial_result · 2024-05-31Clinical Trial Update: SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors [Phase 1]
The SJDAWN Phase 1 trial at St. Jude evaluated molecularly-driven doublet therapies for children and young adults with recurrent brain tumor…
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CLINICAL_TRIALS research · 2024-05-31Clinical Trial Update: T Cells and Pembrolizumab for Recurrent and Newly Diagnosed Glioblastoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating pembrolizumab in combination with T cell therapy for recurrent and newly diagnosed glioblastoma. Th…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Phase 2 Study to Investigate the Efficacy and Safety of Aldoxorubicin in Subjects With Glioblastoma [Phase 2]
Phase 2 study evaluating the efficacy and safety of Aldoxorubicin in glioblastoma has completed, with results posted in 2024-05-29.