Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-05-23Clinical Trial Update: IRD at Admission Predicts Survival of GBM Patients - a Prospective Pilot Study
A completed prospective pilot study evaluating whether IRD at admission predicts survival in patients with glioblastoma.
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CLINICAL_TRIALS trial_result · 2024-05-21Clinical Trial Update: Evaluating the Effect of a Mobile Audio Companion (Elly) to Reduce Anxiety in Cancer Patients [NA]
This clinical trial update notes the completion of a study evaluating Elly, a mobile audio companion, intended to reduce anxiety in cancer p…
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Bavituximab With Radiation and Temozolomide for Patients With Newly Diagnosed Glioblastoma [Phase 2]
Phase 2 trial evaluating bavituximab in combination with radiation and temozolomide for newly diagnosed glioblastoma has completed, with res…
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Lapatinib With Temozolomide and Regional Radiation Therapy for Patients With Newly-Diagnosed Glioblastoma Multiforme [Phase 2]
This Phase 2 trial update reports on combining lapatinib with temozolomide and regional radiation therapy for patients with newly diagnosed …
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CLINICAL_TRIALS research · 2024-05-16Clinical Trial Update: Neoadjuvant Radio-chemotherapy Safety Pilot Study in Patients With Glioblastoma [Phase 1]
A Phase 1 neoadjuvant radiochemotherapy safety pilot study for glioblastoma is currently recruiting at Hospital Universitario San Carlos in …
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CLINICAL_TRIALS trial_result · 2024-05-14Clinical Trial Update: Response Prediction for Anti-angiogenic Treatment in Recurrent Glioblastoma
Completed clinical trial evaluating biomarkers predicting response to anti-angiogenic therapy in recurrent glioblastoma.
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CLINICAL_TRIALS research · 2024-05-14Clinical Trial Update: Advanced MR Imaging as Predictor of Treatment Response in Newly Diagnosed Glioblastomas [NA]
Clinical trial evaluating advanced MRI techniques as predictors of treatment response in newly diagnosed glioblastoma.
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CLINICAL_TRIALS research · 2024-05-10Clinical Trial Update: Glutamate Inhibitors in Glioblastoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial conducted by the University of Zurich is evaluating glutamate inhibitors in patients with glioblastoma and is cur…
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CLINICAL_TRIALS research · 2024-05-09Clinical Trial Update: Escalated Dose Proton Therapy Within the Multimodality Treatment of Glioblastoma Patients [NA]
Update on a clinical trial investigating escalated-dose proton therapy as part of multimodality treatment for glioblastoma.
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Pembrolizumab for Newly Diagnosed Glioblastoma [Phase 2]
An active Phase 2 clinical trial is evaluating pembrolizumab for newly diagnosed glioblastoma, currently not recruiting.
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Glioblastoma Targeted Treatment Option Maximization by WGS [NA]
A clinical trial at UMC Utrecht is exploring whole-genome sequencing–guided, targeted treatment options for glioblastoma and is currently re…
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CLINICAL_TRIALS withdrawal · 2024-05-06Clinical Trial Update: 89Zr-RO5323441 PET Imaging in Glioblastoma [Phase 2]
A Phase 2 trial evaluating the PET imaging agent 89Zr-RO5323441 for glioblastoma has been withdrawn.
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CLINICAL_TRIALS research · 2024-05-02Clinical Trial Update: Clinical Study of Allogeneic Vγ9Vδ2 T Cells in the Treatment of Brain Malignant Glioma [EARLY_Phase 1]
This entry describes an early-stage Phase 1 clinical study evaluating allogeneic Vγ9Vδ2 T cells for malignant gliomas, including glioblastom…
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CLINICAL_TRIALS research · 2024-05-02Clinical Trial Update: A Trial of Neoadjuvant Therapy in Patients With Newly Diagnosed Glioblastoma [Phase 2]
A Phase 2 neoadjuvant therapy trial for newly diagnosed glioblastoma has been terminated.
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CLINICAL_TRIALS trial_result · 2024-05-01Clinical Trial Update: Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma [Phase 2, Phase 3]
This update reports the results of a randomized Phase 2/3 trial comparing ipilimumab and nivolumab with radiation therapy versus the standar…
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CLINICAL_TRIALS trial_result · 2024-04-29Clinical Trial Update: Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas [Phase 1]
Phase 1 clinical trial update evaluating safety and preliminary efficacy of carboxylesterase-expressing allogeneic neural stem cells in comb…
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CLINICAL_TRIALS research · 2024-04-26Clinical Trial Update: Recurrent GBM Treated With Neurosurgical Resection and IORT Using the Xoft Axxent eBx System and Bevacizumab [Phase 2]
A Phase 2 clinical trial evaluating neurosurgical resection followed by intraoperative radiotherapy using the Xoft Axxent eBx System in comb…
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CLINICAL_TRIALS other · 2024-04-25Clinical Trial Update: Expanded Access for KHK2455
Expanded Access for Kyowa Kirin's KHK2455 in glioblastoma multiforme is no longer available.
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CLINICAL_TRIALS trial_result · 2024-04-23Clinical Trial Update: Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations [Phase 2]
Phase 2 clinical trial evaluating veliparib in combination with radiation therapy and temozolomide for newly diagnosed malignant glioma; res…
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CLINICAL_TRIALS trial_result · 2024-04-22Clinical Trial Update: A Trial of Enzastaurin Plus Temozolomide During and Following Radiation Therapy in Patients With Newly Diagnosed Glioblastoma With or Without the Novel Genomic Biomarker, DGM1 [Phase 3]
Phase 3 trial evaluating enzastaurin plus temozolomide with/without a novel biomarker in newly diagnosed glioblastoma; study completed.
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CLINICAL_TRIALS trial_result · 2024-04-15Clinical Trial Update: Study Testing The Safety and Efficacy of Adjuvant Temozolomide Plus TTFields (Optune®) Plus Pembrolizumab in Patients With Newly Diagnosed Glioblastoma (2-THE-TOP) [Phase 2]
Phase 2 trial evaluating the safety and efficacy of adjuvant temozolomide plus TTFields (Optune) and pembrolizumab in newly diagnosed gliobl…
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CLINICAL_TRIALS trial_result · 2024-04-15Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of TJ107 in Lympopenic Patients With Newly Diagnosed Glioblastoma Who Completed Standard Concurrent Chemoradiotherapy (CCRT) [Phase 2]
Phase 2 clinical trial evaluating TJ107 for efficacy and safety in lympopenic patients with newly diagnosed glioblastoma who completed stand…
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CLINICAL_TRIALS trial_result · 2024-04-10Clinical Trial Update: Effectiveness of MR-guided LITT Therapy in Irresectable Glioblastoma (EMITT) [Phase 3]
Phase 3 trial update evaluating MR-guided laser interstitial thermal therapy (LITT) for irresectable glioblastoma (EMITT).
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CLINICAL_TRIALS trial_result · 2024-04-08Clinical Trial Update: Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children [Phase 1]
Phase 1b trial update for PVSRIPO in recurrent malignant glioma in children has completed enrollment and results posted.
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CLINICAL_TRIALS trial_result · 2024-04-08Clinical Trial Update: Immunotherapy Targeted Against Cytomegalovirus in Patients With Newly-Diagnosed WHO Grade IV Unmethylated Glioma [Phase 2]
Phase 2 trial evaluating an immunotherapy targeting cytomegalovirus in newly diagnosed unmethylated glioma (glioblastoma) has been terminate…