Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-08-28Clinical Trial Update: Evaluation of Ad-RTS-hIL-12 + Veledimex in Subjects With Recurrent or Progressive Glioblastoma, a Substudy to ATI001-102 [Phase 1]
Phase 1 substudy update evaluating Ad-RTS-hIL-12 with Veledimex in recurrent or progressive glioblastoma; results have been posted.
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CLINICAL_TRIALS research · 2025-08-27Clinical Trial Update: Investigator-Initiated Study of Imipramine Hydrochloride and Lomustine in Recurrent Glioblastoma [Phase 2]
Clinical trial update describing a Phase 2 investigator-initiated study evaluating imipramine hydrochloride in combination with lomustine fo…
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CLINICAL_TRIALS research · 2025-08-27Clinical Trial Update: Allogeneic γδT Cells in Glioblastoma [NA]
A clinical trial evaluating allogeneic γδT cells in glioblastoma is currently recruiting, sponsored by Peking University Third Hospital.
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: Improving Understanding of Brain Tumors Through Preservation of Biologically Active Brain Tissue [NA]
This clinical trial update describes a study aimed at improving understanding of brain tumors by preserving biologically active brain tissue…
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: ADI-PEG 20 Plus Radiotherapy and Temozolomide in Subjects With Glioblastoma Multiforme [Phase 2]
A Phase 2 clinical trial update on ADI-PEG 20 with radiotherapy and temozolomide for glioblastoma, with the study currently active but not r…
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: Serial MRI Scans During Radiation Therapy [NA]
ClinicalTrials.gov entry for a Dana-Farber Cancer Institute study evaluating serial MRI scans during radiation therapy for glioblastoma and …
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: A Study to Determine How BI 907828 (Brigimadlin) is Taken up in the Tumor (Phase 0) and to Determine the Highest Dose of BI 907828 (Brigimadlin) That Could be Tolerated (Phase 1a) in Combination With Radiation Therapy in People With a Brain Tumor Called Glioblastoma [Phase 1]
The study evaluated how Brigimadlin (BI-907828) is taken up by glioblastoma tumors and identified the highest tolerated dose when given with…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Phase 2 Clinical Trial of KH617 [Phase 2]
A Phase 2 clinical trial of KH617 for recurrent glioblastoma is listed as not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: Pembrolizumab and a Vaccine (ATL-DC) for the Treatment of Surgically Accessible Recurrent Glioblastoma [Phase 1]
Phase 1 study evaluating pembrolizumab in combination with the ATL-DC vaccine for surgically accessible recurrent glioblastoma; current stat…
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CLINICAL_TRIALS trial_result · 2025-08-21Clinical Trial Update: Analyzing Pulsed Reduced Dose Radiotherapy in Upfront Glioblastoma [Phase 2]
A Phase 2 clinical trial update on pulsed reduced dose radiotherapy used upfront for glioblastoma; the study is currently active but not rec…
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: Sonodynamic-Chemoradiotherapy Integration in Glioblastoma [Phase 2]
Phase 2 clinical trial update evaluating sonodynamic-chemoradiotherapy integration for glioblastoma; enrollment is ongoing by invitation.
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: Ph I/II Study of NMS-03305293+TMZ in Adult Patients With Recurrent Glioblastoma [Phase 1, Phase 2]
This update describes a Phase 1/2 trial evaluating the combination of NMS-03305293 and temozolomide in adults with recurrent glioblastoma; t…
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: A Study to Evaluate ERAS-801 in Patients With Recurrent Glioblastoma (THUNDERBBOLT-1) [Phase 1]
A Phase 1 study (THUNDERBBOLT-1) evaluating ERAS-801 in recurrent glioblastoma is active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-08-17Clinical Trial Update: Abemaciclib w/Bevacizumab in Recurrent GBM Pts w/Loss of CDKN2A/B or Gain or Amplification of CDK4/6 [EARLY_Phase 1]
An early-phase 1 trial evaluating abemaciclib in combination with bevacizumab for recurrent glioblastoma with CDKN2A/B loss or CDK4/6 amplif…
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: Lerapolturev (PVSRIPO) in GBM [Phase 2]
Lerapolturev (PVSRIPO) is being studied in a Phase 2 trial for recurrent supratentorial glioblastoma and is currently recruiting.
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: Psychological and Psychiatric prOfile in Glioblastoma and Head and Neck Cancer
This clinical trial study assesses the psychological and psychiatric profiles of patients with glioblastoma and head and neck cancer and is …
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: Glioblastoma Imaging for the Detection of Tumor Progression Using APTw-CEST MRI [NA]
This clinical trial is investigating the use of APTw-CEST MRI imaging to detect tumor progression in glioblastoma.
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CLINICAL_TRIALS trial_result · 2025-08-13Clinical Trial Update: PriCoTTF Study: TTFields Before and During Radiotherapy for Newly Diagnosed Glioblastoma [Phase 1, Phase 2]
This update reports on a Phase 1/2 clinical trial evaluating Tumor Treating Fields (TTFields) therapy before and during radiotherapy for new…
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Molecular Imaging of Cancer-associated Fibroblasts in Glioblastoma: a FAPI PET/MR Study. [NA]
An ongoing clinical trial in glioblastoma is evaluating molecular imaging of cancer-associated fibroblasts using FAPI PET/MR.
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Magnetic Resonance Fingerprinting Guided Extended Resection in Glioblastomas [Phase 1]
Phase 1 trial using magnetic resonance fingerprinting to guide extended surgical resection in patients with glioblastoma; the study is not y…
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CLINICAL_TRIALS trial_result · 2025-08-12Clinical Trial Update: Open-label Study Investigating of OKN-007 Combined With Temozolomide in Patients With Recurrent Glioblastoma [Phase 2]
Open-label Phase 2 trial evaluating OKN-007 in combination with temozolomide for recurrent glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2025-08-12Clinical Trial Update: A Study of Ad-RTS-hIL-12 With Veledimex in Combination With Nivolumab in Subjects With Glioblastoma; a Substudy to ATI001-102 [Phase 1]
A Phase 1 substudy evaluating Ad-RTS-hIL-12 with veledimex in combination with nivolumab for glioblastoma. The ATI001-102 substudy is comple…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: IA Carboplatin + Radiotherapy in Relapsing GBM [Phase 1, Phase 2]
Clinical trial evaluating intra-arterial carboplatin with radiotherapy for relapsed glioblastoma, currently recruiting for Phase 1/Phase 2.
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: PH Sensitive MRI Based Resections of Glioblastoma [Phase 1]
Phase 1 clinical trial evaluating pH-sensitive MRI-guided resections for glioblastoma is currently recruiting.
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CLINICAL_TRIALS withdrawal · 2025-08-11Clinical Trial Update: Abemaciclib + Pembrolizumab In Glioblastoma [Phase 2]
Clinical trial NCT04118036 studying Abemaciclib plus Pembrolizumab in glioblastoma has been withdrawn (Phase 2).