Gastroesophageal Junction Cancer

• CLINICAL_TRIALS trial_result · 2019-03-15
  Clinical Trial Update: Phase II Study Using CHFR Methylation Status in Patients With Metastatic Esophageal, Gastroesophageal, Gastric Cancer. [Phase 2]

  Phase II clinical trial evaluating CHFR methylation status in patients with metastatic esophageal, gastroesophageal, and gastric cancers; st…

• CLINICAL_TRIALS trial_result · 2019-03-13
  Clinical Trial Update: Sorafenib for Patients With Metastatic or Recurrent Esophageal and Gastroesophageal Junction Cancer [Phase 2]

  Phase 2 trial update for sorafenib in metastatic or recurrent esophageal and gastroesophageal junction cancer.

• CLINICAL_TRIALS trial_result · 2019-02-08
  Clinical Trial Update: Celecoxib/Oxaliplatin/Capecitabine for Gastric/Gastroesophageal Junction Carcinoma [Phase 2]

  A Phase 2 trial of Celecoxib in combination with Oxaliplatin and Capecitabine for gastric cancer and gastroesophageal junction cancer has be…

• CLINICAL_TRIALS trial_result · 2018-10-26
  Clinical Trial Update: Docetaxel, Oxaliplatin, and Fluorouracil in Treating Patients With Metastatic or Unresectable Stomach Cancer, Gastroesophageal Junction Cancer, or Other Solid Tumor [Phase 1, Phase 2]

  Phase 1/2 trial evaluating a combination of docetaxel, oxaliplatin, and fluorouracil in patients with metastatic or unresectable stomach/gas…

• CLINICAL_TRIALS trial_result · 2018-10-17
  Clinical Trial Update: Regorafenib in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction Who Have Completed Chemoradiation Therapy and Surgery [Phase 2]

  Phase 2 trial investigating regorafenib for locally advanced esophageal or gastroesophageal junction cancer after chemoradiation and surgery…

• Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
• CLINICAL_TRIALS trial_result · 2018-07-26
  Clinical Trial Update: Preoperative Dose-dense Chemotherapy With Weekly Cisplatin, Epirubicin and Paclitaxel to Treat Patients With Locally Gastric Cancer [Phase 2]

  A Phase 2 trial of preoperative dose-dense chemotherapy with weekly cisplatin, epirubicin and paclitaxel for locally advanced gastric cancer…

• CLINICAL_TRIALS trial_result · 2018-07-18
  Clinical Trial Update: Capecitabine, Oxaliplatin, and Radiation Therapy in Treating Patients With Esophageal or Gastroesophageal Junction Cancer [Phase 2]

  Phase 2 trial evaluating a combination of capecitabine and oxaliplatin with radiation therapy for esophageal or gastroesophageal junction ca…

• CLINICAL_TRIALS withdrawal · 2018-03-26
  Clinical Trial Update: Phase 3 Study of Nimotuzumab and Irinotecan as Second Line With Advanced or Recurrect Gastric and Gastroesophageal Junction Cancer [Phase 3]

  A Phase 3 trial evaluating nimotuzumab plus irinotecan as second-line therapy for advanced or recurrent gastric and gastroesophageal junctio…

• CLINICAL_TRIALS research · 2018-03-20
  Clinical Trial Update: Phase II Trial of Neoadjuvant Treatment and Minimal Invasive Surgery for Esophageal and GEJ Cancer [Phase 2]

  This is an update on a Phase II clinical trial evaluating neoadjuvant therapy plus minimally invasive surgery for esophageal and gastroesoph…

• CLINICAL_TRIALS trial_result · 2018-03-13
  Clinical Trial Update: A Phase 2 Study of Ramucirumab (LY3009806) in Participants With Gastric or Gastroesophageal Junction (GEJ) Cancer [Phase 2]

  Phase 2 study of ramucirumab in gastric and GEJ cancer completed with posted results.

• CLINICAL_TRIALS trial_result · 2018-03-13
  Clinical Trial Update: Panitumumab, Combination Chemotherapy, & Radiation Therapy in Esophageal or Gastroesophageal Junction Cancer [Phase 2]

  Phase 2 trial investigating panitumumab with combination chemotherapy and radiation therapy for esophageal or gastroesophageal junction aden…

• CLINICAL_TRIALS trial_result · 2017-07-11
  Clinical Trial Update: Human Epidermal Growth Factor Receptor 2 (HER2) Advanced Gastric Epidemiology Study in Korea

  This clinical trial update notes that the HER2 Advanced Gastric Epidemiology study in Korea has completed. The sponsor is Hoffmann-La Roche …

• CLINICAL_TRIALS trial_result · 2017-07-06
  Clinical Trial Update: Irinotecan and Cisplatin in Treating Patients Who Are Undergoing Surgery For Locally Advanced Cancer of the Stomach or Gastroesophageal Junction [Phase 2]

  Phase 2 trial results evaluating irinotecan in combination with cisplatin for patients undergoing surgery for locally advanced gastric or ga…

• CLINICAL_TRIALS trial_result · 2017-06-22
  Clinical Trial Update: A Study of MM-111 and Paclitaxel With Trastuzumab in Patients HER2 Positive Carcinomas of the Distal Esophagus, Gastroesophageal (GE) Junction and Stomach [Phase 2]

  A Phase 2 trial evaluating MM-111 in combination with paclitaxel and trastuzumab for HER2-positive distal esophagus, gastroesophageal juncti…

• CLINICAL_TRIALS trial_result · 2017-05-15
  Clinical Trial Update: A Study of MLN0264 in Participants With Cancer of the Stomach or Gastroesophageal Junction [Phase 2]

  A Phase 2 study of MLN0264 in gastric and gastroesophageal junction adenocarcinoma expressing GC-C was terminated. Results were posted in Ma…

• FDA approval · 2017-03-27
  FDA Approved: HERCEPTIN — Supplemental Application (Genentech, Inc.)

  FDA approved a supplemental application for HERCEPTIN (trastuzumab) submitted by Genentech, Inc.

• CLINICAL_TRIALS trial_result · 2017-03-21
  Clinical Trial Update: Sunitinib in Treating Patients With Relapsed or Refractory Esophageal or Gastroesophageal Junction Cancer [Phase 2]

  Phase 2 clinical trial evaluating sunitinib in patients with relapsed or refractory esophageal or gastroesophageal junction cancer; results …

• CLINICAL_TRIALS trial_result · 2017-03-15
  Clinical Trial Update: Cisplatin, Irinotecan, and Radiation Therapy in Treating Patients With Esophageal Cancer or Gastroesophageal Junction Cancer That Can Be Removed By Surgery [Phase 2]

  A Phase 2 clinical trial evaluating cisplatin, irinotecan, and radiation therapy for resectable esophageal cancer or gastroesophageal juncti…

• CLINICAL_TRIALS trial_result · 2017-03-15
  Clinical Trial Update: Combination Chemotherapy and Cetuximab in Treating Patients With Metastatic Esophageal Cancer or Gastroesophageal Junction Cancer [Phase 2]

  Phase 2 trial evaluating combination chemotherapy and cetuximab in metastatic esophageal cancer or gastroesophageal junction cancer has comp…

• CLINICAL_TRIALS trial_result · 2017-03-07
  Clinical Trial Update: Efficacy and Safety of AZD4547 Versus Paclitaxel in Patients With Advanced Gastric or Gastro-oesophageal Cancer [Phase 2]

  Phase 2 trial comparing AZD4547 versus paclitaxel in advanced gastric cancer and gastroesophageal junction cancer was terminated, with resul…

• CLINICAL_TRIALS trial_result · 2017-03-06
  Clinical Trial Update: A Clinical Trial of Apatinib Plus Docetaxel in Locally Advanced or Metastatic Gastric or GEJ Adenocarcinoma [Phase 1]

  Phase 1 clinical trial evaluating the combination of apatinib and docetaxel in locally advanced or metastatic gastric or GEJ adenocarcinoma.

• CLINICAL_TRIALS trial_result · 2017-01-05
  Clinical Trial Update: Treatment of Malignant Strictures in Esophagus and Gastroesophageal Junction With Covered or Partially Covered Stent. [Phase 2]

  A Phase 2 clinical trial evaluating covered or partially covered stents for malignant esophageal and gastroesophageal junction strictures ha…

• CLINICAL_TRIALS trial_result · 2016-12-13
  Clinical Trial Update: Bortezomib, Paclitaxel, and Carboplatin in Treating Patients With Unresectable, Metastatic Cancer of the Esophagus or Gastroesophageal Junction [Phase 2]

  A Phase 2 study evaluating the combination of bortezomib, paclitaxel, and carboplatin in unresectable, metastatic esophageal or gastroesopha…

• CLINICAL_TRIALS trial_result · 2016-11-28
  Clinical Trial Update: A Study of Herceptin (Trastuzumab) in Combination With Cisplatin/Capecitabine Chemotherapy in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Metastatic Gastric or Gastro-Esophageal Junction Cancer [Phase 3]

  A Phase 3 trial of Herceptin with cisplatin and capecitabine in HER2-positive metastatic gastric or gastroesophageal junction cancer was ter…

• CLINICAL_TRIALS trial_result · 2016-11-23
  Clinical Trial Update: Phase I/II Trial of Tivantinib With FOLFOX for the Treatment of Advanced Solid Tumors and Previously Untreated Metastatic Adenocarcinoma of the Distal Esophagus, Gastroesophageal Junction or Stomach [Phase 1, Phase 2]

  Phase I/II trial evaluating tivantinib with FOLFOX for advanced solid tumors including metastatic adenocarcinoma of the distal esophagus, ga…