Gastroesophageal Junction Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-05-06Clinical Trial Update: Total Neoadjuvant FLOT Chemotherapy in Locally Advanced Gastric and Gastroesophageal Junction Cancer [Phase 2, Phase 3]
A Phase 2/Phase 3 trial is evaluating total neoadjuvant FLOT chemotherapy for locally advanced gastric and gastroesophageal junction cancer;…
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CLINICAL_TRIALS research · 2025-04-18Clinical Trial Update: Evaluation of Efficacy and Safety De-escalation Versus Standard Adjuvant Chemotherapy in Patients With Low Risk Localized Gastroesophageal Adenocarcinoma [Phase 2]
Phase 2 clinical trial evaluating de-escalation versus standard adjuvant chemotherapy in patients with low-risk localized gastroesophageal c…
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CLINICAL_TRIALS research · 2025-04-16Clinical Trial Update: The Effect of Different Digestive Tract Reconstruction Methods on Postoperative Quality of Life After Proximal Gastrectomy
This clinical trial investigates how different digestive tract reconstruction methods after proximal gastrectomy affect patients' postoperat…
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: Efficacy of Tirellizumab Combined With Oral, Intravenous and Abdominal Chemotherapy in Peritoneal Metastatic Gastric/Gastroesophageal Junction Adenocarcinoma [Phase 2]
Phase 2 trial evaluating Tirellizumab combined with oral, IV, and intraperitoneal chemotherapy for gastric/gastroesophageal junction/esophag…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: Establishment of 2D and 3D Primary Cell Cultures From Gastric and Gastroesophageal Junction Cancer
The study aims to establish 2D and 3D primary cell cultures from gastric and gastroesophageal junction cancers. This setup supports future t…
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CLINICAL_TRIALS research · 2025-02-17Clinical Trial Update: A Multicenter Randomized Controlled Phase II Trial of Iparomlimab and Tuvonralimab (QL1706) Combined with SOX Chemotherapy Versus Chemotherapy Alone in the Treatment of Locally Advanced Gastric or Gastroesophageal Junction Adenocarcinoma [Phase 2]
A Phase II multicenter randomized trial evaluating iparomlimab and tuvonralimab (QL1706) added to SOX chemotherapy vs chemotherapy alone for…
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CLINICAL_TRIALS research · 2025-02-07Clinical Trial Update: Immune Checkpoint Inhibitors (ICIs) Retreatment in Second-line Treatment of Advanced Gastric Cancer: a Retrospective, Real-world Study
A retrospective real-world study evaluating retreatment with immune checkpoint inhibitors as second-line therapy for advanced gastric cancer…
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: PD-1 Blockade With JS001 Plus Neoadjuvant Chemotherapy for Gastric/Gastroesophageal Junction Cancer [Phase 2]
A Phase 2 clinical trial evaluating JS001 in combination with neoadjuvant chemotherapy for gastric cancer and gastroesophageal junction canc…
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CLINICAL_TRIALS research · 2025-01-29Clinical Trial Update: A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study of the bispecific antibody MCLA-158 in patients with advanced solid tumors. Recruitme…
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CLINICAL_TRIALS research · 2025-01-24Clinical Trial Update: Low-dose Radiotherapy Combined With Chemotherapy and AK112 as Second-line Treatment in Patients With Advanced G/GEJ Cancer [Phase 2]
Phase 2 trial evaluating low-dose radiotherapy combined with chemotherapy and AK112 as second-line treatment for advanced gastric and gastro…
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: The Relationship of Psychological Stress With Therapy Efficacy and Prognosis of Gastric Cancer
A clinical trial exploring how psychological stress influences therapy efficacy and prognosis in gastric cancer and gastroesophageal junctio…
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CLINICAL_TRIALS research · 2025-01-07Clinical Trial Update: A Prospective Cohort Study on the Treatment of Locally Advanced Gastric Cancer
A prospective cohort study investigating treatments for locally advanced gastric cancer; the study is currently recruiting.
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CLINICAL_TRIALS research · 2025-01-06Clinical Trial Update: Locally ablatIVe thErapy for oLigo-progressive gastrOintestiNal maliGnancies (LIVELONG) [NA]
The LIVELONG trial from University of California, Davis is an ongoing study evaluating locally ablative therapy for oligoprogressive gastroi…
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: EPITOME-1015-I: a Study to Investigate the Safety and Tolerability of MDG1015 in Patients with Epithelial Ovarian Cancer, Gastroesophageal Adenocarcinoma, Round Cell Liposarcoma And/or Synovial Sarcoma [Phase 1]
This is a Phase 1 study to evaluate the safety and tolerability of MDG1015 in patients with epithelial ovarian cancer, gastroesophageal junc…
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CLINICAL_TRIALS research · 2024-11-19Clinical Trial Update: A Phase 2 Clinical Study of ABSK061 and ABSK043 [Phase 2]
Abbisko Therapeutics is recruiting for a Phase 2 study of ABSK061 and ABSK043 in multiple cancers, including HER2-positive gastric/gastroeso…
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CLINICAL_TRIALS research · 2024-10-28Clinical Trial Update: IMmune Proteomics to Predict neoAdjuvant Chemotherapy and immunoTherapy Response in Gastric Cancer
Clinical trial investigating immune proteomics to predict response to neoadjuvant chemotherapy and immunotherapy in gastric cancer; currentl…
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CLINICAL_TRIALS research · 2024-10-22Clinical Trial Update: A Study of MRG002 in Patients with HER2-Positive Advanced Solid Tumors and Locally Advanced or Metastatic Gastric/Gastroesophageal Junction (GEJ) Cancer [Phase 1, Phase 2]
Clinical trial update on MRG002 in patients with HER2-positive advanced solid tumors and locally advanced or metastatic gastric/GEJ cancer, …
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CLINICAL_TRIALS research · 2024-10-17Clinical Trial Update: Phase IIT Trial of SNA014 [EARLY_Phase 1]
Early-phase trial update for SNA014 by SmartNuclide Biopharma targeting gastric and gastroesophageal junction adenocarcinomas; the study is …
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: MRI and CT in Gastroesophageal Junction or Upper Gastric Adenocarcinoma
This clinical trial update describes an imaging study using MRI and CT in patients with gastric cancer or gastroesophageal junction cancer. …
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CLINICAL_TRIALS research · 2024-10-04Clinical Trial Update: Radical Surgery for Advanced Gastric- or GEJ-cancer With Oligometastatic Dissmination to the Liver [NA]
A clinical trial is evaluating radical surgery for advanced gastric or gastroesophageal junction cancer with limited liver metastases. The s…
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CLINICAL_TRIALS research · 2024-07-17Clinical Trial Update: A Phase II Trial of Perioperative Adebrelimab Combined With XELOX in Resectable Locally Advanced Gastric/Gastroesophageal Junction Cancer (GC/GEJC) [Phase 2]
This document describes an ongoing Phase II trial investigating perioperative adebrelimab in combination with XELOX for patients with resect…
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CLINICAL_TRIALS research · 2024-07-11Clinical Trial Update: Neoadjuvant Serplulimab in Combination With Chemotherapy in Locally Advanced Gastric or Gastro-esophageal Junction Cancer [Phase 2]
This Phase 2 trial is evaluating neoadjuvant serplulimab with chemotherapy for locally advanced gastric or gastroesophageal junction cancer.…
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CLINICAL_TRIALS research · 2024-06-07Clinical Trial Update: Perioperative Surufatinib Plus Sintilimab Combined With Chemotherapy in Gastric/Gastroesophageal Junction Adenocarcinoma [Phase 2]
Phase 2 clinical trial update evaluating perioperative surufatinib plus sintilimab with chemotherapy for gastric cancer and gastroesophageal…
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CLINICAL_TRIALS research · 2024-06-03Clinical Trial Update: Adjuvant Treatment With Serplulimab，Trastuzumab and SOX in the HER-2 Positive GC/GEJC [Phase 2]
A Phase 2 clinical trial update evaluating adjuvant therapy with serplulimab, trastuzumab, and the SOX regimen (S-1 plus oxaliplatin) for HE…
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CLINICAL_TRIALS research · 2024-05-07Clinical Trial Update: The Efficacy and Safety of Tislelizumab Combined With Anlotinib and S1 Plus Oxaliplatin as Neoadjuvant Therapy for the Locally Advanced Adenocarcinoma of Esophagogastric Junction [Phase 2]
A Phase 2 neoadjuvant trial evaluating a combination of tislelizumab, anlotinib, S-1, and oxaliplatin for locally advanced adenocarcinoma of…