Gastroesophageal Junction Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Study of AZD5863 in Adult Participants With Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 study of AZD5863 in adults with advanced or metastatic solid tumors is currently recruiting, including gastric cancer, gastroeso…
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Totally Versus Hybrid Minimally Invasive Esophagectomy for Esophageal Cancer [NA]
A clinical trial comparing totally minimally invasive versus hybrid minimally invasive esophagectomy for resectable esophageal or gastroesop…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2 [Phase 2]
Phase 2 clinical trial evaluating AZD0901 in advanced solid tumours expressing Claudin18.2 is currently recruiting, including gastric cancer…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: A Phase III Study of SHR-A1811 in Combination With Chemotherapy and Adebrelimab in Previously Untreated Patients With Gastric or Gastroesophageal Junction Adenocarcinoma [Phase 3]
A Phase III trial evaluating SHR-A1811 with chemotherapy and Adebrelimab in untreated, unresectable or metastatic gastric or gastroesophagea…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: First-line Treatment of Gastric or Gastroesophageal Junction Adenocarcinoma With Dual Immunotherapy Combined With Chemotherapy [Phase 2]
A Phase 2 trial evaluating first-line dual immunotherapy plus chemotherapy for gastric or gastroesophageal junction adenocarcinoma; the stud…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Abemaciclib Plus Ramucirumab for Esophageal/Gastroesophageal Junction Ca [Phase 1, Phase 2]
An ongoing Phase 1/2 study of abemaciclib plus ramucirumab for metastatic esophageal adenocarcinoma and metastatic gastroesophageal junction…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Albumin-bound Paclitaxel-based Second-line Treatment Regimens for Locally Advanced or Metastatic G/GEJ Adenocarcinoma
This clinical trial update reports ongoing recruitment for second-line regimens based on albumin-bound paclitaxel to treat locally advanced …
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Trans-Pacific Multicenter Collaborative Study of Minimally Invasive Proximal Versus Total Gastrectomy for Proximal Gastric and Gastroesophageal Junction Cancers
This multicenter clinical trial compares minimally invasive proximal gastrectomy with total gastrectomy for proximal gastric and gastroesoph…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Phase 1/2 Study to Evaluate TH9619 in the Treatment of Advanced Solid Tumors [Phase 1, Phase 2]
This clinical trial update indicates that TH9619 is being studied in a Phase 1/2 trial for advanced solid tumors, with recruitment ongoing a…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Study to Assess the Effect of OCT-598 in Patients With Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial evaluating OCT-598 in patients with advanced solid tumors; the study is currently recruiting and includes multiple tu…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Clinical Efficacy of Pucotenlimab Combined With Lenvatinib and SOX Versus SOX Alone in Patients With HER2-Negative Advanced Gastric or Gastroesophageal Junction Adenocarcinoma [EARLY_Phase 1]
An early-phase (Phase 1) study evaluating pucotenlimab in combination with lenvatinib and the SOX regimen versus SOX alone in HER2-negative …
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Study to Evaluate the Efficacy and Safety of Camrelizumab and Apatinib in Patients With GC/GEJC [Phase 3]
A Phase 3 clinical trial is evaluating the efficacy and safety of combining Camrelizumab with Apatinib in patients with gastric cancer and g…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Trastuzumab Deruxtecan to Treat HER2 + Newly Diagnosed Metastatic GI Cancers [Phase 2]
Phase 2 trial update evaluating trastuzumab deruxtecan for HER2-positive newly diagnosed metastatic esophageal, gastric, and gastroesophagea…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Factors Influencing Immunotherapy Response in dMMR/MSI-H Gastric/Gastroesophageal Junction Adenocarcinoma [Phase 2]
A Phase 2 clinical trial is exploring factors that influence immunotherapy response in mismatch repair-deficient or MSI-H gastric and gastro…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Iparomlimab and Tuvonralimab (QL1706) Combined With Chemotherapy for Previously Untreated Advanced or Metastatic Gastric or Gastroesophageal Junction Cancer [Phase 2]
A Phase 2 trial evaluating the combination of Iparomlimab and Tuvonralimab (QL1706) with chemotherapy in previously untreated advanced or me…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Assessing Durvalumab and FLOT Chemotherapy in Resectable Gastric and Gastroesophageal Junction Cancer [Phase 3]
A Phase 3 trial evaluating the combination of durvalumab with the FLOT chemotherapy regimen in resectable gastric and gastroesophageal junct…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Aldesleukin With Nivolumab and Standard Chemotherapy for Treatment of Gastric Cancer With Peritoneal Metastasis [Phase 1]
This is a Phase 1 clinical trial evaluating Aldesleukin in combination with Nivolumab and standard chemotherapy for clinical stage IV gastri…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma
Ongoing Stanford University clinical trial evaluating clinical and pathological aspects of upper gastrointestinal cancers, including stomach…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Combination of Osemitamab (TST001), Pembrolizumab and Chemotherapy as First-line Therapy in Advanced or Metastatic GC/GEJ Adenocarcinoma [Phase 3]
This clinical trial update describes a Phase 3 study evaluating a triplet regimen of Osemitamab (TST001), pembrolizumab, and chemotherapy as…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: A Trial to Evaluate Safety and Tolerability of TST001 in Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
Clinical trial update for TST001 in advanced or metastatic solid tumors (Phase 1/2); the study is currently active and not recruiting.
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Claudin 18.2-Targeted Chimeric Antigen Receptor T-cells in Subjects With Unresectable, Locally Advanced, or Metastatic Gastric, Gastroesophageal Junction (GEJ), Esophageal, or Pancreatic Adenocarcinoma [Phase 1]
Phase 1 clinical trial evaluating Claudin 18.2-targeted CAR-T cells in unresectable/locally advanced or metastatic gastric, gastroesophageal…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: A Study Evaluating Bemarituzumab in Combination With Other Anti-cancer Therapies in Subjects With Previously Untreated Advanced Gastric or Gastroesophageal Junction Cancer. [Phase 1, Phase 2]
Phase 1/Phase 2 clinical trial update on bemarituzumab in combination with other anti-cancer therapies for previously untreated advanced gas…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: The Efficacy and Safety of Laparoscopic Proximal Gastrectomy With LPG-tbROSF Versus LTG for Localized Proximal Gastric Cancer. [NA]
This clinical trial assesses the efficacy and safety of laparoscopic proximal gastrectomy with LPG-tbROSF versus laparoscopic total gastrect…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: A Study of agenT-797 in Combination With Botensilimab, Balstilimab, Ramucirumab, and Paclitaxel for People With Esophageal, Gastric, or Gastro-esophageal Junction Cancer [Phase 2]
Phase 2 clinical trial update reporting ongoing recruitment for a combination therapy (agenT-797 with Botensilimab, Balstilimab, Ramucirumab…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Utidelone Capsule Combined With Fluoropyrimidine- and Platinum-containing Therapy in First-line Treatment of Patients With Gastric or Gastroesophageal Junction Adenocarcinoma [Phase 2, Phase 3]
A Phase 2/3 clinical trial evaluating Utidelone capsules in combination with fluoropyrimidine- and platinum-containing therapy as first-line…