Friedreich Ataxia
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CLINICAL_TRIALS trial_result · 2015-04-30Clinical Trial Update: Interferon Gamma-1b in Friedreich Ataxia (FRDA) [Phase 2]
Phase 2 trial of Interferon Gamma-1b in Friedreich Ataxia completed; results posted in 2015.
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CLINICAL_TRIALS trial_result · 2014-01-22Clinical Trial Update: A Study of Resveratrol as Treatment for Friedreich Ataxia [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating resveratrol for Friedreich Ataxia has completed. The study was sponsored by Murdoch Children's Researc…
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CLINICAL_TRIALS trial_result · 2013-09-04Clinical Trial Update: Effect of Pioglitazone Administered to Patients With Friedreich's Ataxia: Proof of Concept [Phase 3]
A Phase 3 trial of pioglitazone in Friedreich's ataxia has been completed. The study provides a proof-of-concept for this approach.
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CLINICAL_TRIALS trial_result · 2013-05-21Clinical Trial Update: Efficacy of EGb761 in Patients Suffering From Friedreich Ataxia [Phase 2]
A Phase 2 trial evaluating EGb761 for Friedreich Ataxia has completed with posted results.
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CLINICAL_TRIALS trial_result · 2012-07-24Clinical Trial Update: Pilot Study of Varenicline (Chantix®) in the Treatment of Friedreich's Ataxia [Phase 2, Phase 3]
The phase 2/3 pilot trial of varenicline (Chantix) for Friedreich's Ataxia was terminated.
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CLINICAL_TRIALS trial_result · 2011-12-29Clinical Trial Update: Study to Assess the Efficacy, Safety and Tolerability of Idebenone in the Treatment of Friedreich's Ataxia [Phase 3]
Phase 3 trial assessing idebenone for Friedreich's ataxia completed with posted results.
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CLINICAL_TRIALS trial_result · 2011-08-04Clinical Trial Update: Study to Assess the Safety and Tolerability of Idebenone in the Treatment of Friedreich's Ataxia Patients [Phase 3]
Phase 3 trial update on idebenone for Friedreich's ataxia; study completed with results posted in 2011.
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CLINICAL_TRIALS trial_result · 2011-06-27Clinical Trial Update: A Study Investigating the Long-term Safety and Efficacy of Deferiprone in Patients With Friedreich's Ataxia [Phase 2]
This document reports the completion of a Phase 2 study evaluating the long-term safety and efficacy of deferiprone in patients with Friedre…
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CLINICAL_TRIALS trial_result · 2011-04-22Clinical Trial Update: Safety and Efficacy Study of A0001 in Subjects With Friedreich's Ataxia [Phase 2]
Phase 2 safety and efficacy study of A0001 in Friedreich's Ataxia has completed.
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CLINICAL_TRIALS trial_result · 2010-06-02Clinical Trial Update: A Study Investigating the Safety and Tolerability of Deferiprone in Patients With Friedreich's Ataxia [Phase 1, Phase 2]
The Phase 1/2 study evaluating the safety and tolerability of deferiprone in Friedreich's ataxia has completed.
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CLINICAL_TRIALS trial_result · 2010-05-27Clinical Trial Update: Efficacy of Epoetin Alfa in Patients With Friedreich's Ataxia [Phase 2]
Phase 2 trial evaluating epoetin alfa for Friedreich's ataxia has completed enrollment and reported efficacy results.
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EMA withdrawal · 2009-12-31EMA Refused: Sovrima (idebenone) — Centocor B.V.
The EMA refused the marketing authorization for Sovrima (idebenone) by Centocor B.V. for Friedreich ataxia.
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CLINICAL_TRIALS trial_result · 2009-03-04Clinical Trial Update: Iron-Chelating Therapy and Friedreich Ataxia [Phase 1, Phase 2]
This document reports the completion of a Phase 1/Phase 2 clinical trial evaluating an iron-chelating therapy for Friedreich Ataxia.
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Transitional Life Events in Patients With Friedreich's Ataxia: Implications for Genetic Counseling
This clinical trial update summarizes transitional life events observed in Friedreich's Ataxia patients and discusses implications for genet…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Phase 1 Trial of Idebenone to Treat Patients With Friedreich's Ataxia [Phase 1]
Phase 1 trial of idebenone to treat Friedreich's ataxia has completed.
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CLINICAL_TRIALS research · 2006-07-12Clinical Trial Update: Safety Study of Idebenone to Treat Friedreich's Ataxia [Phase 1]
Notes completion of a Phase 1 safety study evaluating idebenone for Friedreich's ataxia.