Extensive-stage Small Cell Lung Cancer
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: Low-dose Radiotherapy Combined with Concurrent Chemotherapy, Toripalimab and Tifcemalimab in the Treatment of ES-SCLC [Phase 1]
This document describes a Phase 1 clinical trial evaluating the combination of low-dose radiotherapy with concurrent chemotherapy, toripalim…
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CLINICAL_TRIALS research · 2024-12-19Clinical Trial Update: A Real-World Assessment of the Demographic, Clinical Characteristics and Outcomes of a Brazilian Cohort of Previously Untreated Extensive Stage-Small Cell Lung Cancer Receiving Durvalumab Combined With Platinum-Etoposide in (ES-SCLC) in Brazil
A real-world study in Brazil evaluates demographic, clinical characteristics and outcomes of previously untreated extensive-stage small cell…
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CLINICAL_TRIALS research · 2024-12-05Clinical Trial Update: Addition of Thoracic Consolidation Radiotherapy to the Maintenance Immunotherapy for ES-SCLC (STONE-001) [Phase 3]
A Phase 3 trial (STONE-001) is evaluating the addition of thoracic consolidation radiotherapy to maintenance immunotherapy for extensive-sta…
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CLINICAL_TRIALS trial_result · 2024-11-27Clinical Trial Update: Durvalumab Plus Chemotherapy in ES-SCLC (Oriental) [Phase 3]
A Phase 3 trial of durvalumab plus chemotherapy in extensive-stage small cell lung cancer has completed and posted results.
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CLINICAL_TRIALS research · 2024-11-21Clinical Trial Update: Efficacy and Safety of First-line Treatment for Extensive-stage Small Cell Lung Cancer Using a Combination Therapy of Trilaciclib, Envafolimab, Etoposide, and Carboplatin [Phase 2]
A Phase 2 trial evaluating first-line therapy for extensive-stage small cell lung cancer using a combination of trilaciclib, envafolimab, et…
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CLINICAL_TRIALS research · 2024-11-15Clinical Trial Update: A Phase 1/2a Study of 23ME-00610 in Patients With Advanced Solid Malignancies [Phase 1, Phase 2]
Clinical trial registry entry for a Phase 1/2a study of 23ME-00610 in patients with advanced solid malignancies, including several gynecolog…
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CLINICAL_TRIALS research · 2024-11-05Clinical Trial Update: Adebrelimab Combined with Chemotherapy and Thoracic Radiotherapy for First-line Treatment of ES-SCLC [Phase 3]
Phase 3 trial evaluating Adebrelimab with chemotherapy and thoracic radiotherapy as first-line treatment for extensive-stage small cell lung…
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: Auto-HSCT-Supported Dose-Dense Chemotherapy with Adebrelimab As First-Line Treatment for ES-SCLC [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating auto-HSCT-supported dose-dense chemotherapy plus adebrelimab as first-line treatment for extensive-sta…
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CLINICAL_TRIALS trial_result · 2024-09-26Clinical Trial Update: Bomedemstat and Maintenance Immunotherapy for Treatment of Newly Diagnosed Extensive Stage Small Cell Lung Cancer [Phase 1, Phase 2]
Clinical trial update on bomedemstat with maintenance immunotherapy in newly diagnosed extensive-stage or limited-stage small cell lung canc…
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CLINICAL_TRIALS research · 2024-09-26Clinical Trial Update: A Study of Adebelimab Combined With Chemotherapy as a First-line Treatment Sequential Treatment for Extensive-stage Small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial evaluating adebelimab in combination with chemotherapy as first-line treatment for extensive-stage small cell lung …
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: First-line Treatment for ES-SCLC with Chemotherapy Combined with PD-1/PD-L1 Inhibitor Sequential Thoracic Radiotherapy [Phase 2]
A Phase 2 study is evaluating first-line treatment of extensive-stage small-cell lung cancer using chemotherapy combined with a PD-1/PD-L1 i…
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CLINICAL_TRIALS trial_result · 2024-08-23Clinical Trial Update: QUILT-2.013: First-Line Treatment for Extensive Stage Small Cell Lung Cancer [Phase 1, Phase 2]
This entry reports on the QUILT-2.013 first-line treatment study for extensive-stage small cell lung cancer (Phase 1/2) sponsored by NantCel…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Efficacy and Safety of Serplulimab With Chemotherapy and Aspirin in Untreated Extensive-Stage Small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial is evaluating serplulimab in combination with chemotherapy and aspirin for untreated extensive-stage small cell lun…
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: Radiotherapy to All Residual Lesions After Chemoimmunotherapy [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating radiotherapy to all residual lesions after chemoimmunotherapy in extensive-stage small cell lung cance…
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CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: A Multicenter Real-World Cohort Study of Adebrelimab Injection in the Treatment of Extensive-Stage Small Cell Lung Cancer
This update outlines a multicenter real-world cohort study evaluating Adebrelimab injections for extensive-stage small cell lung cancer, whi…
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CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: Study of Low-Dose Radiotherapy (LDRT) Concurrent Cisplatin/Carboplatin Plus Etoposide With Atezolizumab for Patients With Extensive-Stage Small Cell Lung Cancer [Phase 2]
A Phase 2 trial evaluating low-dose radiotherapy with cisplatin/carboplatin, etoposide, and atezolizumab in extensive-stage small cell lung …
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CLINICAL_TRIALS trial_result · 2024-07-24Clinical Trial Update: IMFINZI Study in Patients With Extensive Stage Small Cell Lung Cancer
A study evaluating durvalumab (Imfinzi) in patients with extensive-stage small cell lung cancer has completed.
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CLINICAL_TRIALS other · 2024-07-12Clinical Trial Update: Maintenance Lurbinectedin in Combination With Serplulimab for Patients With ES-SCLC [Phase 2]
A Phase 2 trial update for maintenance lurbinectedin in combination with serplulimab in extensive-stage small cell lung cancer; the study is…
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CLINICAL_TRIALS trial_result · 2024-07-10Clinical Trial Update: Phase 3 Study Evaluating Efficacy, Safety and Pharmacokinetics of Trilaciclib In Small Cell Lung Cancer Patients [Phase 3]
Phase 3 trial evaluating trilaciclib for efficacy, safety, and pharmacokinetics in extensive-stage small cell lung cancer has completed and …
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CLINICAL_TRIALS research · 2024-07-08Clinical Trial Update: A Study to Investigate the Efficacy and Safety of Ivonescimab Combined With Irinotecan Liposome as Second-line Regimen for ES-SCLC [Phase 2]
Phase 2 clinical trial update evaluating Ivonescimab with liposomal irinotecan as second-line therapy for extensive-stage small cell lung ca…
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CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: SHR-1316 Combined With Chemotherapy and Chest Radiotherapy in ES-SCLC [Phase 2]
A Phase 2 clinical trial evaluating SHR-1316 with chemotherapy and chest radiotherapy for extensive-stage small cell lung cancer, currently …
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CLINICAL_TRIALS research · 2024-06-20Clinical Trial Update: Phase I/II Trial in ES-SCLC to Enhance Response to Atezolizumab Plus Chemotherapy With Total Body Irradiation [Phase 1, Phase 2]
A Phase I/II clinical trial in extensive-stage small cell lung cancer is evaluating the addition of total body irradiation to atezolizumab p…
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CLINICAL_TRIALS research · 2024-06-20Clinical Trial Update: Study of Low-Dose Radiotherapy Concurrent Chemotherapy With Serplulimab for Patients With ES-SCLC [Phase 2]
Phase 2 trial evaluating low-dose radiotherapy with concurrent chemotherapy and serplulimab for extensive-stage small-cell lung cancer; the …
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CLINICAL_TRIALS withdrawal · 2024-06-05Clinical Trial Update: Lurbinectedin Combined With Durvalumab in Pre-treated Patients With Extensive Stage Small-cell Lung Cancer [Phase 2]
A Phase 2 trial evaluating lurbinectedin with durvalumab in pre-treated patients with extensive-stage small-cell lung cancer has been withdr…
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: Toripalimab Plus Anlotinib for the Maintenance of Extensive Stage Small Cell [Phase 3]
Phase 3 trial evaluating toripalimab plus anlotinib as maintenance therapy for extensive-stage small cell lung cancer; the study status is n…