Extensive-stage Small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-05-31Clinical Trial Update: Anti-PD-1 and VEGF Bispecific Antibody AK112 in Combination With Chemotherapy in Patients With ES-SCLC [Phase 1]
Phase 1 trial results for AK112, a PD-1/VEGF bispecific antibody, in combination with chemotherapy for extensive-stage small cell lung cance…
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CLINICAL_TRIALS research · 2024-05-13Clinical Trial Update: Safety and Tolerability of LDRT+Sugemalimab+Chemotherapy+Olaparib for First-Line Treatment of SLFN-11 Positive ES-SCLC [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating safety and tolerability of a regimen combining low-dose radiotherapy, sugemalimab, chemotherapy, and ola…
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CLINICAL_TRIALS trial_result · 2024-04-03Clinical Trial Update: Combination of Atezolizumab With Dendritic Cell Vaccine in Patients With Lung Cancer [Phase 1, Phase 2]
A phased clinical trial evaluating atezolizumab combined with a dendritic cell vaccine in patients with extensive-stage small cell lung canc…
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CLINICAL_TRIALS trial_result · 2024-03-04Clinical Trial Update: FR901228 in Treating Patients With Refractory or Progressive Small Cell Lung Cancer or Non-small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial of FR901228 in patients with refractory or progressive small cell lung cancer or non-small cell lung cancer has compl…
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CLINICAL_TRIALS trial_result · 2024-02-02Clinical Trial Update: A Study of Carboplatin Plus Etoposide With or Without ZKAB001 (Anti-PD-L1 Antibody) in Patients With ES-SCLC [Phase 3]
Phase 3 trial evaluating carboplatin and etoposide with or without ZKAB001 (anti-PD-L1) in extensive-stage small-cell lung cancer has comple…
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CLINICAL_TRIALS trial_result · 2024-01-12Clinical Trial Update: Low-dose Radiotherapy Combined With Durvalumab, Chemotherapy(EP) in the Treatment of ES-SCLC [Phase 2]
Phase 2 clinical trial evaluating low-dose radiotherapy with durvalumab and chemotherapy for extensive-stage small-cell lung cancer (ES-SCLC…
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CLINICAL_TRIALS trial_result · 2023-12-20Clinical Trial Update: Guadecitabine in Combination With Carboplatin in Extensive Stage Small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating guadecitabine in combination with carboplatin for extensive-stage small cell lung cancer has completed with posted …
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CLINICAL_TRIALS trial_result · 2023-11-15Clinical Trial Update: Resiliency Among Older Adults Receiving Lung Cancer Treatment [NA]
Clinical trial involving older adults receiving lung cancer treatment has completed; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-10-06Clinical Trial Update: Evaluation of TRILACICLIB in Chinese Patients With Extensive-stage Small Cell Lung Cancer (ES-SCLC) for Chemotherapy-induced Myelosuppression, Antitumor Effects of Combination Regimens, and Safety in a Real-world Study [Phase 4]
Phase 4 trial evaluating trilaciclib in Chinese patients with extensive-stage small cell lung cancer for chemotherapy-induced myelosuppressi…
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CLINICAL_TRIALS trial_result · 2023-08-04Clinical Trial Update: Study of Selinexor Combined With Olaparib in Relapsed/Refractory Extensive Stage Small Cell Lung Cancer [Phase 1, Phase 2]
A clinical trial evaluating the combination of selinexor and olaparib in relapsed/refractory extensive-stage small cell lung cancer is ongoi…
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CLINICAL_TRIALS trial_result · 2023-06-27Clinical Trial Update: Testing the Addition of an Anti-cancer Drug, Entinostat, to the Usual Chemotherapy and Immunotherapy Treatment (Atezolizumab, Carboplatin and Etoposide) for Previously Untreated Aggressive Lung Cancer That Has Spread [Phase 1]
This Phase 1 trial evaluates adding Entinostat to standard chemo-immunotherapy (atezolizumab, carboplatin, etoposide) for previously untreat…
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CLINICAL_TRIALS trial_result · 2023-06-23Clinical Trial Update: Cisplatin/Carboplatin and Etoposide With or Without Nivolumab in Treating Patients With Extensive Stage Small Cell Lung Cancer [Phase 2]
A Phase 2 trial evaluated cisplatin/carboplatin and etoposide with or without nivolumab in patients with extensive-stage small cell lung can…
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CLINICAL_TRIALS trial_result · 2023-06-09Clinical Trial Update: A Study to Investigate the Efficacy and Safety of Tislelizumab Combined With Anlotinib as Maintenance Therapy for ES-SCLC [Phase 2]
A Phase 2 trial evaluating tislelizumab plus anlotinib as maintenance therapy for extensive stage small cell lung cancer is ongoing with sta…
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CLINICAL_TRIALS trial_result · 2023-06-02Clinical Trial Update: Vorolanib + Atezolizumab as Maintenance Therapy for Extensive-Stage Small Cell Lung Cancer [Phase 2]
A Phase 2 trial evaluating vorolanib in combination with atezolizumab as maintenance therapy for extensive-stage small cell lung cancer has …
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CLINICAL_TRIALS trial_result · 2022-12-30Clinical Trial Update: Surufatinib in Combination of Durvalumab and EP/EC in the Firstly-line Treatment of ES-SCLC [Phase 2]
Phase 2 clinical trial evaluating surufatinib with durvalumab and EP/EC as first-line treatment for extensive-stage small-cell lung cancer.
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CLINICAL_TRIALS trial_result · 2022-06-14Clinical Trial Update: A Study of Concurrent Chemoradiation With Atezolizumab in Participants With Untreated Extensive-Stage (ES) Small Cell Lung Cancer (SCLC) [Phase 2]
Phase 2 study evaluating concurrent chemoradiation with atezolizumab in untreated extensive-stage small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2022-06-09Clinical Trial Update: Trilaciclib (G1T28) in Patients With Previously Treated Extensive Stage SCLC Receiving Topotecan Chemotherapy [Phase 1, Phase 2]
Phase 1/2 trial update evaluating Trilaciclib (G1T28) to reduce chemotherapy-induced myelosuppression in patients with previously treated ex…
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CLINICAL_TRIALS trial_result · 2022-02-11Clinical Trial Update: Study of Ponatinib in Patients With Lung Cancer Preselected Using Different Candidate Predictive Biomarkers [Phase 2]
Phase 2 trial evaluating ponatinib in lung cancer patients preselected by predictive biomarkers; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-09-09Clinical Trial Update: A Phase II, Study to Determine the Preliminary Efficacy of Novel Combinations of Treatment in Patients With Platinum Refractory Extensive-Stage Small-Cell Lung Cancer [Phase 2]
Phase II trial evaluating novel combinations for platinum-refractory extensive-stage small cell lung cancer; the study is completed and resu…
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CLINICAL_TRIALS trial_result · 2021-03-10Clinical Trial Update: a Study of SHR1210 in Combination With Paclitaxel-albumin and Carboplatin in Extensive Stage Small Cell Lung Cancer [Phase 2]
Phase 2 trial update evaluating SHR1210 in combination with paclitaxel-albumin and carboplatin for extensive stage small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2020-12-21Clinical Trial Update: A Study of Niraparib as Maintenance Therapy Following First-Line Platinum-Based Chemotherapy in Patients With Extensive Stage Small Cell Lung Cancer [Phase 3]
A Phase 3 trial evaluating niraparib as maintenance therapy after first-line platinum chemotherapy in extensive-stage small cell lung cancer…
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CLINICAL_TRIALS trial_result · 2020-12-19Clinical Trial Update: Anlotinib Plus Platinum-etoposide in First-line of Extensive-stage Small-cell Lung Cancer [Phase 2]
Phase 2 trial update evaluating anlotinib in combination with platinum-etoposide as first-line therapy for extensive-stage small-cell lung c…
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CLINICAL_TRIALS trial_result · 2020-04-28Clinical Trial Update: First-line Chemotherapy Followed by Toripalimab Combined With Anlotinib for Maintenance in ES-SCLC [Phase 2]
Phase 2 trial update evaluating first-line chemotherapy followed by toripalimab plus anlotinib for maintenance in extensive-stage small cell…
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CLINICAL_TRIALS trial_result · 2020-03-18Clinical Trial Update: Anlotinib In Combination With PD-1/L1 Inhibitor As Sequential Therapy of Thoracic Radiotherapy After Induction Chemotherapy For Extensive-Stage Small Cell Lung Cancer:A Single Arm Study [Phase 2]
Phase 2 single-arm trial evaluating anlotinib with a PD-1/PD-L1 inhibitor as sequential therapy following thoracic radiotherapy after induct…
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CLINICAL_TRIALS trial_result · 2020-02-05Clinical Trial Update: This Phase II/III, Multicenter Study is Designed to Evaluate the Safety and Clinical Activity of AL3810 in Patients [Phase 2, Phase 3]
A multicenter Phase II/III trial is designed to evaluate the safety and clinical activity of AL3810 in extensive-stage small cell lung cance…