Extensive-stage Small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-17Clinical Trial Results: A Study of BMS-986012 in Combination With Carboplatin, Etoposide, and Nivolumab as First-line Therapy in Extensive-stage Small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial evaluating BMS-986012 with carboplatin, etoposide, and nivolumab as first-line therapy for extensive-stage small cell…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carboplatin, and Etoposide in First-line Extensive Stage Small-Cell Lung Cancer (ES-SCLC) [Phase 3]
A Phase 3 trial in first-line extensive-stage small-cell lung cancer compares Tarlatamab plus Durvalumab with Carboplatin and Etoposide to D…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease [Phase 1]
A Phase 1 clinical trial evaluating a patient-derived autologous B7-H3 CAR-T cell therapy in previously treated extensive-stage small cell l…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Bispecific T-Cell Engager Tarlatamab and TROP2 Targeted Antibody Drug Conjugate Sacituzumab Govitecan in Previously Treated Extensive-Stage Small Cell Lung Cancer and Extrapulmonary Neuroendocrine Cancer [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study evaluating Tarlatamab and Sacituzumab Govitecan in previously treated extensive-stage…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Tislelizumab Combined With Chemotherapy and Thoracic Radiotherapy in ES-SCLC [Phase 2]
A Phase 2 clinical trial evaluates tislelizumab in combination with chemotherapy and thoracic radiotherapy for extensive-stage small-cell lu…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Study of Sacituzumab Govitecan With Atezolizumab/Durvalumab as Maintenance Therapy for Extensive-Stage Small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating sacituzumab govitecan with atezolizumab and durvalumab as maintenance therapy for extensive-stage small cell lung c…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Nab-Paclitaxel Combined With Local Therapy in Relapsed SCLC [Phase 2]
This is a Phase 2 trial evaluating nab-paclitaxel with local therapy for relapsed small cell lung cancer (extensive stage). The study status…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial [Phase 2, Phase 3]
The RAPTOR trial is evaluating the addition of radiation therapy to atezolizumab for extensive-stage small cell lung cancer and is currently…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Phase II Study of Platinum/Etoposide Plus Ivonescimab for Extensive-Stage Small Cell Lung Cancer [Phase 2]
A Phase II clinical trial updating the study of platinum/etoposide chemotherapy plus Ivonescimab for extensive-stage small cell lung cancer …
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Study to Compare the Efficacy and Safety of BMS-986489 (BMS-986012+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS). [Phase 3]
A Phase 3 trial comparing BMS-986489 (BMS-986012 + nivolumab fixed-dose combination) plus carboplatin and etoposide versus atezolizumab plus…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: A Trial of Tarlatamab in Patients With Pretreated Extensive-stage Small Cell Lung Cancer (ES-SCLC) and ECOG PS 2 [Phase 2]
Phase 2 study evaluating Tarlatamab in pretreated extensive-stage small cell lung cancer with ECOG performance status 2 is currently recruit…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: A Study Comparing BL-B01D1 Combined With Tislelizumab Versus Platinum-containing Chemotherapy Combined With Tislelizumab as First-line Treatment in Patients With Extensive-stage Small Cell Lung Cancer(PANKU-Lung07) [Phase 3]
This Phase 3 trial (PANKU-Lung07) compares BL-B01D1 plus tislelizumab versus platinum-containing chemotherapy plus tislelizumab as first-lin…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemotherapy [Phase 3]
Phase 3 trial (DAREON-Lung-1) evaluating Obrixtamig plus atezolizumab with carboplatin and etoposide versus standard chemotherapy in advance…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Safety, Preliminary Effectiveness of BNT327, an Investigational Therapy for Patients With Small-cell Lung Cancer in Combination With Chemotherapy [Phase 2]
Phase 2 trial update reporting safety and early effectiveness signals for BNT327 in combination with chemotherapy for small-cell lung cancer…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Study Evaluating Tarlatamab in Chinese Participants With Advanced Small Cell Lung Cancer After Two or More Prior Lines of Treatment [Phase 2]
Phase 2 study evaluating tarlatamab in Chinese participants with extensive-stage small cell lung cancer after two or more prior lines of the…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: MGC018 in Patients With Relapsed or Refractory Extensive-Stage Small-Cell Lung Cancer [Phase 2]
Phase 2 trial update reporting results for MGC018 in relapsed or refractory extensive-stage small-cell lung cancer; the study is not current…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing Maintenance Therapy for Small Cell Lung Cancer in Patients With SLFN11 Positive Biomarker [Phase 2]
Phase 2 clinical trial sponsored by the National Cancer Institute evaluating maintenance therapy for extensive-stage small cell lung cancer …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Study of RYZ101 in Combination With SoC in Subjects With SSTR+ ES-SCLC [Phase 1]
This document describes an ongoing Phase 1 trial evaluating RYZ101 in combination with standard of care for somatostatin receptor-positive e…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Sacituzumab Tirumotecan in Combination With Anlotinib in Previously Treated Patients With Extensive-Stage Small Cell Lung Cancer (ES-SCLC) [Phase 2]
A Phase 2 clinical trial evaluating sacituzumab tirumotecan in combination with anlotinib for previously treated extensive-stage small cell …
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Anlotinib Plus Durvalumab-Platinum-Etoposide in First-line Treatment Extensive Small-cell Lung Cancer [Phase 2]
Phase 2 trial evaluating first-line anlotinib plus durvalumab with platinum-etoposide for extensive-stage small-cell lung cancer has complet…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: LB-100, Carboplatin, Etoposide, and Atezolizumab for the Treatment of Untreated Extensive-Stage Small Cell Lung Cancer [Phase 1]
Phase 1 trial evaluating LB-100 in combination with carboplatin, etoposide, and atezolizumab for untreated extensive-stage small cell lung c…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: MOnaliZumab in Combination With durvAlumab (MEDI4736) for tRreatmenT of Small Cell Lung Cancer [Phase 2]
Phase 2 trial of Monalizumab in combination with durvalumab for small cell lung cancer is currently suspended.
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: A Study of Valemetostat in Combination With Atezolizumab in People With Lung Cancer [Phase 1]
An ongoing Phase 1 clinical trial is evaluating valemetostat in combination with atezolizumab for extensive-stage small cell lung cancer. Th…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study [Phase 2]
Phase 2 PRISM trial uses biomarker tests to guide selection of personalized therapies for extensive-stage small cell lung cancer; currently …
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: MDT-Based Nursing for Small Cell Lung Cancer During Chemo-Immunotherapy [NA]
This completed clinical trial evaluated multidisciplinary-team-based nursing for patients with small cell lung cancer during chemo-immunothe…