Ewing Sarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults [Phase 1]
Phase 1 clinical trial update describing B7H3-targeted CAR T-cell therapy for recurrent/refractory pediatric solid tumors, including several…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults [Phase 1]
A Phase 1 trial update for EGFR806 CAR T cell immunotherapy in pediatric and young adult patients with recurrent/refractory solid tumors; th…
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: Cabozantinib With Ifosfamide in Relapsed/Refractory Sarcomas [Phase 1]
A Phase 1 trial evaluating the combination of cabozantinib with ifosfamide in relapsed/refractory sarcomas is currently recruiting at Childr…
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CLINICAL_TRIALS trial_result · 2025-10-21Clinical Trial Update: A Study of INCB059872 in Relapsed or Refractory Ewing Sarcoma [Phase 1]
The Phase 1 study of INCB059872 in Ewing sarcoma has been terminated.
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CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors [Phase 1]
Phase 1 pediatric trial evaluating alpha/beta CD19+ depleted haploidentical transplantation in combination with Zoledronic acid (Zometa) for…
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CLINICAL_TRIALS research · 2025-10-10Clinical Trial Update: Machine Learning Applied to EHRs Data of Patients With Sarcoma
Completed study from the University of Milano Bicocca applying machine learning to electronic health records of patients with sarcoma (inclu…
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CLINICAL_TRIALS other · 2025-10-07Clinical Trial Update: Combination of Pembrolizumab and Cabozantinib in Patients With Advanced Sarcomas [Phase 2]
A Phase 2 trial evaluating the combination of pembrolizumab and cabozantinib in advanced soft tissue sarcomas, including Ewing sarcoma, oste…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors [Phase 1]
Phase 1 study evaluating flavored oral irinotecan VAL-413 (Orotecan) with temozolomide for recurrent pediatric solid tumors is currently rec…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: A Phase II Study Evaluating Efficacy and Safety of Regorafenib in Patients With Metastatic Bone Sarcomas [Phase 2]
Phase II clinical trial evaluating regorafenib for metastatic bone sarcomas is active but not recruiting, including Ewing sarcoma, chondrosa…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: A Post-treatment Program to Identify and Manage Complications Related to Oncology or Hematology Treatments in Cancer Survivors. [NA]
This clinical trial update describes a post-treatment program to identify and manage complications related to oncology or hematology treatme…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Fertility Preservation in Children With Solid Tumors: Detection of Residual Disease by a Sensitive Method
This clinical trial investigates fertility preservation in children with solid tumors and evaluates detection of residual disease using a hi…
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: A Study of [225Ac]-FPI-2059 in Adult Participants With Solid Tumours [Phase 1]
A Phase 1 study of [225Ac]-FPI-2059 in adults with solid tumours was terminated.
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CLINICAL_TRIALS trial_result · 2025-08-15Clinical Trial Update: A Study of LY2880070 and Gemcitabine in People With Ewing Sarcoma,Ewing-Like Sarcoma, and Desmoplastic Small Round Cell Tumor [Phase 2]
Phase 2 study of LY-2880070 in combination with gemcitabine for Ewing sarcoma, Ewing-like sarcoma, and desmoplastic small round cell tumor h…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: A Randomized Controlled Study Comparing the Safety and Efficacy of Irinotecan Hydrochloride Liposome Injection Combined With Temozolomide and Vincristine (NALIRI-VT) Versus Irinotecan Combined With Temozolomide and Vincristine (VIT) in Patients With Advanced Ewing's Sarcoma [Phase 2]
A Phase 2 randomized trial comparing liposomal irinotecan-based combination therapy (NALIRI-VT) with standard irinotecan-based therapy (VIT)…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: C7R-GD2.CART Cells for Patients With Relapsed or Refractory Neuroblastoma and Other GD2 Positive Cancers (GAIL-N) [Phase 1]
ClinicalTrials.gov entry updates the Phase 1 study of C7R-GD2.CART cells for relapsed or refractory GD2-positive cancers, including neurobla…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: The Risk of Acute Myeloid Leukaemia in Patients With Ewing's Sarcoma
This clinical trial update discusses the risk of developing acute myeloid leukemia in patients diagnosed with Ewing Sarcoma. The study statu…
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CLINICAL_TRIALS research · 2025-07-15Clinical Trial Update: Sequential Infusion of CD146-Targeted and HER2-Targeted CAR T Cells in Patients With Advanced Sarcomas [Phase 1, Phase 2]
A clinical trial update describing a Phase 1/2 study of sequential infusion of CD146-targeted and HER2-targeted CAR T cells in patients with…
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: Donor Stem Cell Transplant After Chemotherapy for the Treatment of Recurrent or Refractory High-Risk Solid Tumors in Pediatric and Adolescent-Young Adults [Phase 2]
A Phase 2 trial evaluating donor stem cell transplant after chemotherapy for recurrent or refractory high-risk solid tumors in pediatric and…
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CLINICAL_TRIALS other · 2025-06-05Clinical Trial Update: Expanded Access of Vigil in Solid Tumors
The expanded access program for Vigil in solid tumors, including Ewing sarcoma, is temporarily not available.
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial [Phase 2]
Phase 2 pediatric MATCH trial results for Tipifarnib in HRAS-altered solid tumors and histiocytic disorders; the study has posted results an…
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: Phase II Study of Irinotecan Liposome (II) Combined With Temozolomide and Fluzoparib in Recurrent or Metastatic Ewing Sarcoma [Phase 2]
Phase II trial evaluating a triplet regimen of liposomal irinotecan, temozolomide, and fluzoparib for recurrent or metastatic Ewing sarcoma;…
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: Early Ageing During Therapy in AYA Cancer Patients
A clinical trial investigating early ageing during therapy in adolescents and young adults with cancer is currently recruiting. The study co…
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: DFMO Maintenance for Patients With Relapsed/Refractory Ewing Sarcoma or Osteosarcoma [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial evaluating maintenance therapy with DFMO for relapsed or refractory Ewing sarcoma and osteosarcoma is curre…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Collecting and Storing Tissue From Young Patients With Cancer
A completed clinical trial update from the Children’s Oncology Group describing the collection and storage of tissue from pediatric cancer p…
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CLINICAL_TRIALS research · 2025-04-20Clinical Trial Update: Tissue Expression of Krüppel-Like Factors 4 and 7 in Bone Tumors
A recruiting study examining tissue expression of Krüppel-like factors 4 and 7 in pediatric bone tumors, including osteosarcoma and Ewing sa…