Ewing Sarcoma
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: CAMPFIRE: A Study of Abemaciclib (LY2835219) in Participants With Ewing's Sarcoma [Phase 2]
CAMPFIRE is a Phase 2 study of Abemaciclib (LY2835219) in participants with Ewing sarcoma. Results were posted on March 12, 2026.
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Liposomal Irinotecan, Vincristine, Temozolomide, and Anlotinib for R/R Pediatric Solid Tumors [Phase 2]
This clinical trial update outlines a Phase 2 study evaluating a combination of liposomal irinotecan, vincristine, temozolomide, and anlotin…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Phase 1/2 Trial to Evaluate the Safety and Efficacy of PEEL-224 in Combination With Vincristine and Temozolomide in Adolescents and Young Adults With Relapsed or Refractory Sarcomas [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating the safety and potential efficacy of PEEL-224 in combination with vincristine and temozolomide in a…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies [Phase 1]
This clinical trial update describes a Phase 1/1B study of ST-01156, a small-molecule RBM39 degrader, in patients with advanced solid tumors…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Testing a New Combination of Anti-cancer Drugs in Patients Newly Diagnosed With Ewing Sarcoma Who Have Cancer That Has Spread to Other Parts of the Body [Phase 2, Phase 3]
A phase 2/3 clinical trial sponsored by the Children's Oncology Group is evaluating a new combination of anti-cancer drugs for patients newl…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone Sarcomas [NA]
Investigates regorafenib as maintenance therapy after first-line treatment in patients with bone sarcomas and related subtypes. The trial is…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Hypofractionated Radiation in Combination With B7-H3-CAR T Cells for Pediatric Patients With Relapsed/Refractory Sarcomas [Phase 1]
Phase 1 clinical trial in pediatric relapsed/refractory sarcomas evaluating hypofractionated radiation in combination with B7-H3-CAR T cells…
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas [Phase 1]
Phase 1 study evaluating CD45RA+ depleted haploidentical stem cell transplantation in children with relapsed or refractory solid tumors and …
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: A Study to Evaluate the Utilization of 3D Printed Models in Pre-Operative Planning [NA]
A clinical study sponsored by Ricoh USA, Inc. is evaluating the use of 3D-printed models to assist pre-operative planning for various sarcom…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Long Term Brain Toxicity of Chemotherapy in Patients Treated for a Bone TumorDuring Childhood or Adolescence [NA]
This clinical trial update describes long-term brain toxicity from chemotherapy in adults who were treated for osteosarcoma or Ewing sarcoma…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Diffusion Weighted Magnetic Resonance in Imaging Younger Patients With Newly Diagnosed Bone or Soft Tissue Sarcomas [NA]
A completed clinical trial update examining diffusion-weighted MRI imaging in younger patients with newly diagnosed bone or soft-tissue sarc…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma [Phase 1, Phase 2]
A pediatric and young adult phase 1/2 trial is studying lurbinectedin as monotherapy for relapsed/refractory Ewing sarcoma; recruitment is o…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Adherence to a Personalized Home Exercise Program in Patients With Bone Tumor Undergoing Lower Extremity Salvage Surgery
This clinical trial update notes a study evaluating adherence to a personalized home exercise program for bone tumor patients undergoing low…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Selective Antigen Specific T Cells and CAR T Cells in Subjects With Relapsed/Refractory Embryonal Tumors (SABRE) [Phase 1]
Phase 1 SABRE trial evaluating selective antigen-specific T cells and CAR T cells in relapsed/refractory embryonal tumors, including rhabdom…
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: Elimusertib for the Treatment of Relapsed or Refractory Solid Tumors [Phase 1, Phase 2]
Clinical trial update reporting Phase 1/2 results for Elimusertib in relapsed or refractory solid tumors, including alveolar rhabdomyosarcom…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Biologically-Adapted, Dose-Escalated Radiotherapy for the Treatment of Ewing Sarcoma, BEAR Trial [NA]
The BEAR trial is a Mayo Clinic-sponsored study of biologically adapted, dose-escalated radiotherapy for Ewing sarcoma and related round cel…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcoma [Phase 1]
Phase 1 clinical trial evaluating HER2-targeted CAR T cells in combination with checkpoint blockade for advanced sarcoma; recruitment is ong…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Liquid Biopsy in Ewing Sarcoma and Osteosarcoma as a Prognostic And Response Diagnostic: LEOPARD [NA]
The LEOPARD trial is evaluating liquid biopsy as a prognostic and response diagnostic tool for Ewing sarcoma (bone and soft tissue), Periphe…
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma [Phase 2]
Phase 2 trial update for eflornithine (DFMO) in osteosarcoma and Ewing sarcoma (including metastatic disease) indicates the study is not yet…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Phase Ib / Regorafenib With Conventional Chemotherapy/Newly Diagnosed Patients/ Multimetastatic Ewing Sarcoma [Phase 1]
This entry describes a Phase 1 trial of regorafenib with conventional chemotherapy for newly diagnosed multimetastatic Ewing sarcoma. The st…
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: Observational Study on Skeletal Ewing's Sarcoma
An observational study on skeletal Ewing sarcoma is currently recruiting. Sponsored by the Italian Sarcoma Group.
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Phase I Study of Olaparib and Temozolomide for Ewings Sarcoma or Rhabdoomyosarcoma [Phase 1]
A completed Phase I clinical trial evaluated the combination of olaparib and temozolomide in patients with Ewing sarcoma and rhabdomyosarcom…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: SARC037: A Phase I/II Study to Evaluate the Safety of Trabectedin in Combination With Irinotecan in Ewing Sarcoma Patients [Phase 1, Phase 2]
Phase I/II trial evaluating the safety of combining trabectedin with irinotecan in Ewing sarcoma has completed.
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: Nab-Paclitaxel and Gemcitabine for Recurrent/Refractory Sarcoma [Phase 2]
A Phase 2 trial of nab-paclitaxel plus gemcitabine for recurrent or refractory sarcoma has completed and posted results.
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: First-line Treatment of Ewing Tumours With Primary Extrapulmonary Dissemination in Patients From 2 to 50 Years (CombinaiR3) [Phase 2]
The document reports the completion of a Phase 2 clinical trial (CombinaiR3) evaluating first-line treatment for Ewing sarcoma with primary …