Ewing Sarcoma
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial) [Phase 2]
Phase 2 update from the Pediatric MATCH trial describes targeted therapies matched to tumor genetics in pediatric patients with relapsed or …
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma [Phase 1, Phase 2]
A pediatric Phase 1/2 study is evaluating Onivyde (liposomal irinotecan) in combination with talazoparib or temozolomide in children with re…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01) [Phase 1, Phase 2]
Substudy 01A of MK-9999-01A (LIGHTBEAM-U01) evaluates Zilovertamab Vedotin in pediatric and young adult participants with hematologic malign…
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Lurbinectedin in FET-Fused Tumors [Phase 1, Phase 2]
Phase 1/2 trial evaluates Lurbinectedin in FET-fused tumors such as Ewing sarcoma and desmoplastic small round cell tumor. Recruitment is on…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 pediatric MATCH trial evaluating IDH1-mutant tumors for response to ivosidenib; results for recurrent and refractory solid tumors, l…
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: A Clinical Study of TK216 in Patients With Relapsed or Refractory Ewing's Sarcoma [Phase 2]
This update concerns a Phase 2 study of TK216 in relapsed or refractory Ewing sarcoma. The trial status is listed as completed.
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: Vincristine and Temozolomide in Combination With PEN-866 for Adolescents and Young Adults With Relapsed or Refractory Solid Tumors [Phase 1, Phase 2]
An NCI-sponsored Phase 1/2 trial of vincristine and temozolomide with PEN-866 in adolescents and young adults with relapsed or refractory so…
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: CAMPFIRE: A Study of Abemaciclib (LY2835219) in Participants With Ewing's Sarcoma [Phase 2]
CAMPFIRE is a Phase 2 study of Abemaciclib (LY2835219) in participants with Ewing sarcoma. Results were posted on March 12, 2026.
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas [Phase 1]
Phase 1 study evaluating CD45RA+ depleted haploidentical stem cell transplantation in children with relapsed or refractory solid tumors and …
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: Elimusertib for the Treatment of Relapsed or Refractory Solid Tumors [Phase 1, Phase 2]
Clinical trial update reporting Phase 1/2 results for Elimusertib in relapsed or refractory solid tumors, including alveolar rhabdomyosarcom…
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma [Phase 2]
Phase 2 trial update for eflornithine (DFMO) in osteosarcoma and Ewing sarcoma (including metastatic disease) indicates the study is not yet…
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Phase I Study of Olaparib and Temozolomide for Ewings Sarcoma or Rhabdoomyosarcoma [Phase 1]
A completed Phase I clinical trial evaluated the combination of olaparib and temozolomide in patients with Ewing sarcoma and rhabdomyosarcom…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: SARC037: A Phase I/II Study to Evaluate the Safety of Trabectedin in Combination With Irinotecan in Ewing Sarcoma Patients [Phase 1, Phase 2]
Phase I/II trial evaluating the safety of combining trabectedin with irinotecan in Ewing sarcoma has completed.
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: Nab-Paclitaxel and Gemcitabine for Recurrent/Refractory Sarcoma [Phase 2]
A Phase 2 trial of nab-paclitaxel plus gemcitabine for recurrent or refractory sarcoma has completed and posted results.
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: First-line Treatment of Ewing Tumours With Primary Extrapulmonary Dissemination in Patients From 2 to 50 Years (CombinaiR3) [Phase 2]
The document reports the completion of a Phase 2 clinical trial (CombinaiR3) evaluating first-line treatment for Ewing sarcoma with primary …
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CLINICAL_TRIALS trial_result · 2025-10-21Clinical Trial Update: A Study of INCB059872 in Relapsed or Refractory Ewing Sarcoma [Phase 1]
The Phase 1 study of INCB059872 in Ewing sarcoma has been terminated.
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: A Study of [225Ac]-FPI-2059 in Adult Participants With Solid Tumours [Phase 1]
A Phase 1 study of [225Ac]-FPI-2059 in adults with solid tumours was terminated.
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CLINICAL_TRIALS trial_result · 2025-08-15Clinical Trial Update: A Study of LY2880070 and Gemcitabine in People With Ewing Sarcoma,Ewing-Like Sarcoma, and Desmoplastic Small Round Cell Tumor [Phase 2]
Phase 2 study of LY-2880070 in combination with gemcitabine for Ewing sarcoma, Ewing-like sarcoma, and desmoplastic small round cell tumor h…
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: Donor Stem Cell Transplant After Chemotherapy for the Treatment of Recurrent or Refractory High-Risk Solid Tumors in Pediatric and Adolescent-Young Adults [Phase 2]
A Phase 2 trial evaluating donor stem cell transplant after chemotherapy for recurrent or refractory high-risk solid tumors in pediatric and…
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial [Phase 2]
Phase 2 pediatric MATCH trial results for Tipifarnib in HRAS-altered solid tumors and histiocytic disorders; the study has posted results an…
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Quality of Life of Patients With Bone Tumor of the Lower Limbs Treated With Salvage Surgery
This completed clinical trial evaluates quality of life in patients with lower-limb bone tumors treated with salvage surgery.
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor [Phase 1]
Phase 1 trial evaluating a conditioning regimen of busulfan, melphalan, and topotecan hydrochloride followed by stem cell transplantation in…
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: Phase 2 STIR Trial: Haploidentical Transplant and Donor Natural Killer Cells for Solid Tumors [Phase 2]
Phase 2 trial update of haploidentical transplantation with donor natural killer cells for solid tumors; the study was terminated and result…
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: Radiation Therapy to Treat Musculoskeletal Tumors [Phase 2]
A Phase 2 clinical trial evaluating radiation therapy for musculoskeletal tumors has posted results (as of 2025-03-06). The study is current…
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CLINICAL_TRIALS trial_result · 2025-02-28Clinical Trial Update: Β3-adrenoreceptor As Prognostic Marker in Neuroblastoma and Ewing Sarcoma [NA]
This completed clinical trial evaluates Beta-3 adrenergic receptor as a prognostic biomarker in neuroblastoma and Ewing sarcoma.