Esophageal Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Prospective, Open-label, Multi-cohort Study of Becotatug Vedotin With Tislelizumab and Chemotherapy in Esophageal Squamous Cell Carcinoma - Phase 2 [Phase 2]
A Phase 2 open-label, multi-cohort study evaluating Becotatug Vedotin in combination with Tislelizumab and chemotherapy for esophageal squam…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Intensive Nutritional Support in Conversion Therapy for Locally Advanced Unresectable ESCC [Phase 2]
Phase 2 clinical trial update for intensive nutritional support as conversion therapy in locally advanced unresectable esophageal squamous c…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Study of XB010 in Subjects With Solid Tumors [Phase 1]
A Phase 1 trial evaluating XB010 in locally advanced or metastatic solid tumors is currently recruiting across multiple indications.
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Phase Ib/II Study of an Anti-HER3 Antibody, HMBD-001, With Cetuximab +/- Docetaxel in Advanced Squamous Cell Cancers [Phase 1, Phase 2]
A Phase Ib/II clinical trial evaluating HMBD-001, an anti-HER3 antibody, in combination with cetuximab with or without docetaxel for advance…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Short-Course Definitive Chemoradiotherapy Combined With Adjuvant or Concurrent Plus Adjuvant Camrelizumab for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma [Phase 2]
A Phase 2 clinical trial is evaluating short-course definitive chemoradiotherapy with camrelizumab given concurrently or as adjuvant therapy…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Efficacy and Safety of Adebrelimab Combined With Chemoradiotherapy in Patients With Unresectable Locally Advanced or Postoperative Recurrent Esophageal Squamous Cell Carcinoma [Phase 2]
Clinical trial update on the efficacy and safety of Adebrelimab with chemoradiotherapy in patients with unresectable locally advanced or pos…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: A Study to Investigate Tislelizumab (BGB-A317) Versus Placebo in Combination With Concurrent Chemoradiotherapy in Participants With Localized Esophageal Squamous Cell Carcinoma [Phase 3]
A Phase 3 trial comparing tislelizumab plus concurrent chemoradiotherapy versus placebo with chemoradiotherapy in localized esophageal squam…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors [Phase 1]
Plexium, Inc. is conducting a first-in-human Phase 1 study of PLX-61639 in locally advanced or metastatic solid tumors, and the trial is cur…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas [Phase 1]
Phase 1 study evaluating safety, efficacy, and pharmacokinetics of EVOLVE104 in patients with advanced urothelial cancer and squamous cell c…
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CLINICAL_TRIALS other · 2026-04-13Clinical Trial Update: SHR-1701 in Combination With Irinotecan Liposome (II) for Second-line Treatment of ESCC After Immunotherapy [Phase 2]
Phase 2 trial evaluating SHR-1701 in combination with liposomal irinotecan for second-line esophageal squamous cell carcinoma after immunoth…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Phase 2 Futibatinib in Combination With PD-1 Antibody Based Standard of Care in Solid Tumors [Phase 2]
Phase 2 study evaluating futibatinib in combination with a PD-1 antibody-based standard of care for locally advanced unresectable or metasta…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Perioperative Toripalimab (JS001) Combined With Neoadjuvant Chemotherapy in Patients With Resectable Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma [Phase 3]
Phase 3 trial evaluating perioperative toripalimab in combination with neoadjuvant chemotherapy for patients with resectable locally advance…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: A Prospective Study of Physical Function in Adults Who Receive Systemic Therapy for Stage I-III Gastroesophageal Cancer, FAST-GO Study
This Clinical Trials update describes the FAST-GO prospective study evaluating physical function in adults receiving systemic therapy for st…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors [Phase 1]
Pfizer's Phase 1 study PF-08046876 is recruiting adults with various advanced solid tumors to evaluate safety and dosing. The trial includes…
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: A Trial of ChAdOx1 and MVA Vaccines Against MAGE-A3 and NY-ESO-1 [Phase 1, Phase 2]
A Phase 1/2 trial evaluating ChAdOx1 and MVA vaccines targeting MAGE-A3 and NY-ESO-1 for non-small cell lung cancer and esophageal squamous …
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer [Phase 3]
A Phase 3 clinical trial comparing proton therapy to photon radiation therapy for esophageal cancer across multiple stages and histologies i…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Observational Study of Patients Treated With Nivolumab and Chemotherapy for Advanced or Metastatic Esophageal, Gastroesophageal or Gastric Cancer in France
An observational study in France evaluating outcomes for patients with advanced gastric and esophageal cancers treated with nivolumab in com…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial update for IDE892 evaluating monotherapy and combination in MTAP-deleted advanced solid tumors. The study is currentl…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Neoadjuvant Camrelizumab With Palbociclib for Resectable Esophageal Squamous Cell Carcinomas [Phase 1]
Phase 1 neoadjuvant trial investigating camrelizumab with palbociclib for resectable esophageal squamous cell carcinoma; the study is curren…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Camrelizumab, Chemotherapy and Ivarmacitinib in Patients With Resectable Esophageal Squamous Cell Carcinoma [Phase 2]
A Phase 2 trial investigating camrelizumab with chemotherapy and ivaramacitinib as neoadjuvant therapy for resectable esophageal squamous ce…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types [Phase 1]
IDEAYA Biosciences is conducting a Phase 1 study of IDE034 in adults with multiple locally advanced or metastatic solid tumors; the trial is…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06) [Phase 1, Phase 2]
Umbrella trial MK-3475-06E (KEYMAKER-U06) is evaluating pembrolizumab-based combination therapies for Esophageal Squamous Cell Carcinoma and…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: A Study of YL201 Versus Investigator's Choice of Chemotherapy in Participants With Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma After Failure of First-Line Therapy [Phase 3]
Phase 3 clinical trial comparing YL201 to investigator's choice chemotherapy in locally advanced or metastatic esophageal squamous cell carc…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Safety of RAD301 in Healthy Human Volunteers and Patients With Pancreatic Cancer or Other Solid Tumors [Phase 1]
Phase 1 trial update on the safety of RAD301 in healthy volunteers and patients with pancreatic ductal adenocarcinoma or other solid tumors;…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Pilot Study of [68Ga]Ga-ABY-025 Imaging in Patients Undergoing Treatment With HER2-targeted Therapy [EARLY_Phase 1]
This is a pilot early-phase imaging trial evaluating the HER2-targeted PET tracer [68Ga]Ga-ABY-025 in patients undergoing HER2-targeted ther…