Esophageal Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Hypofractionated vs. Conventional Chemoradiotherapy After Induction Chemo-immunotherapy for Unresectable Esophageal Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial comparing hypofractionated versus conventional chemoradiotherapy after induction chemo-immunotherapy for unresectable…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Induction Immuno-chemotherapy and Concurrent Chemoradiotherapy With or Without Apatinib in Unresectable, Locally Advanced Esophageal Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial update evaluating induction immuno-chemotherapy and concurrent chemoradiotherapy with or without apatinib for unresec…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Study to Evaluate LBL-007 in Combination With Tislelizumab Plus Chemotherapy in Participants With Unresectable Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma [Phase 2]
The document reports an ongoing Phase 2 clinical trial evaluating LBL-007 in combination with tislelizumab and chemotherapy for unresectable…
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CLINICAL_TRIALS research · 2025-10-06Clinical Trial Update: Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers [NA]
A UCSF-led clinical trial is evaluating radiation therapy for metastatic gastrointestinal cancers, and the study is currently recruiting.
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: A Single-arm, Open, Single-center Exploratory Study of Adebrelimab (SHR-1316) in Combination With Chemotherapy for the Perioperative Treatment of Locally Advanced Resectable Esophageal Squamous Carcinoma [Phase 2]
A Phase 2, single-arm, open-label exploratory trial evaluating adebrelimab (SHR-1316) in combination with chemotherapy for perioperative tre…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: A Retrospective Cohort Study of Patients Who Underwent Curative-intent Esophagectomy for ESCC at a Tertiary Referral Center in South Korea
A retrospective cohort study evaluating outcomes of patients with esophageal squamous cell carcinoma who underwent curative-intent esophagec…
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: TAS-102 Plus Radiotherapy in Elderly ESCC [Phase 1, Phase 2]
This document reports a Phase 1/2 clinical trial evaluating TAS-102 in combination with radiotherapy for elderly patients with esophageal sq…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: SI-B001 Combined With Irinotecan in the Treatment of Recurrent Metastatic Esophageal Squamous Cell Carcinoma. [Phase 2]
Phase 2 clinical trial update evaluating SI-B001 in combination with irinotecan for recurrent metastatic esophageal squamous cell carcinoma.…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Neoadjuvant Camrelizumab With Palbociclib for Resectable Esophageal Squamous Cell Carcinoma [Phase 2]
This is a Phase 2 neoadjuvant trial evaluating the combination of camrelizumab and palbociclib for resectable esophageal squamous cell carci…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Ivonescimab Plus Short-Course Hypofractionated Radiotherapy as Second-Line Therapy for Esophageal Squamous Cell Carcinoma [Phase 2]
A Phase 2 clinical trial evaluating Ivonescimab plus short-course hypofractionated radiotherapy as second-line therapy for esophageal squamo…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Biomarker Based Neoadjuvant Strategies for Locally Advanced Resectable ESCC [Phase 2]
Phase 2 clinical trial update on biomarker-based neoadjuvant strategies for locally advanced resectable esophageal squamous cell carcinoma, …
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Low-Dose Radiotherapy in Patients With Advanced Esophageal Squamous Cell Carcinoma Resistant to First-Line Chemotherapy Combined With Immunotherapy [Phase 2]
Phase 2 trial not yet recruiting evaluating low-dose radiotherapy in patients with advanced esophageal squamous cell carcinoma resistant to …
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: Chemoradiation and Pembrolizumab Followed by Pembrolizumab and Lenvatinib Before Surgery for the Treatment of Non-metastatic Esophageal or Esophageal/Gastroesophageal Junction Cancer [Phase 2]
A Phase 2 clinical trial update evaluating chemoradiation with pembrolizumab, followed by pembrolizumab and lenvatinib before surgery for no…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Brachytherapy With Radiotherapy and Immunotherapy: Guided HDR Trial in Esophageal Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial evaluating brachytherapy with radiotherapy and immunotherapy for esophageal squamous cell carcinoma, sponsored by Nat…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Multi-omics Monitoring of Dynamic Evolution in Esophageal Squamous Cell Carcinoma: PKU-ESCC-Monitor
A ClinicalTrials.gov entry from Peking University Cancer Hospital & Institute describes an upcoming study using multi-omics monitoring to st…
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CLINICAL_TRIALS research · 2025-08-29Clinical Trial Update: Predictive Biomarkers for PD-1 Inhibitor Response in Squamous Cell Carcinoma
This clinical trial update discusses predictive biomarkers for response to PD-1 inhibitors in squamous cell carcinomas, spanning esophageal,…
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CLINICAL_TRIALS research · 2025-08-29Clinical Trial Update: Neoadjuvant ChemoRadiotherapy Followed by Immunotherapy and Surgery for Resectable Esophageal Squamous Cell Carcinoma（CRIS-2 Trial） [Phase 2]
A Phase 2 trial (CRIS-2) is evaluating neoadjuvant chemoradiotherapy followed by immunotherapy and surgery for resectable esophageal squamou…
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: A Single-center, Multicohort, Phase II Clinical Study Evaluating the Combination Therapy of Sacituzumab Tirumotecan in Patients With Unresectable, Locally Advanced, Recurrent, or Metastatic Esophageal Squamous Cell Carcinoma [Phase 2]
A Phase II clinical trial is evaluating the combination of Sacituzumab Tirumotecan in patients with unresectable, locally advanced, recurren…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Lymphocyte-sparing Thoracic Radiotherapy for Esophageal Squamous Cell Carcinoma [NA]
This clinical trial update notes a study on lymphocyte-sparing thoracic radiotherapy for esophageal squamous cell carcinoma, sponsored by Ru…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: A Phase II Clinical Study of Induction Adebrelimab Combined With Chemotherapy Followed by Concurrent Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma (ESCC) [Phase 2]
Phase II clinical trial evaluating induction adebrelimab with chemotherapy followed by concurrent chemoradiotherapy for locally advanced unr…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: A Clinical Study on the Efficacy and Safety of Paclitaxel Polymeric Micelles and Cisplatin Combined With Cadonilimab as a Neoadjuvant Therapy for Locally Advanced Esophageal Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial evaluating paclitaxel polymeric micelles and cisplatin with cadonilimab as neoadjuvant therapy for locally advanced e…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Deep Learning Model Predicts Pathological Complete Response of Esophageal Squamous Cell Carcinoma Following Neoadjuvant Immunochemotherapy
A clinical trial update describes a deep learning model that predicts pathological complete response in esophageal squamous cell carcinoma a…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: An Observational Study on the Safety and Efficacy of Immunotherapy Combined With Concurrent Chemoradiotherapy in Elderly Patients With Esophageal Squamous Cell Carcinoma
An observational study evaluating the safety and efficacy of immunotherapy combined with concurrent chemoradiotherapy in elderly patients wi…
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CLINICAL_TRIALS research · 2025-07-21Clinical Trial Update: Fraction Dose Escalation of Split-course Hypofractionated Concurrent Chemoradiotherapy Following Induction Chemo-immunotherapy in Unresectable Locally Advanced Esophageal Squamous Carcinoma: a Phase I Study. [Phase 1]
Phase I trial evaluating dose escalation of split-course hypofractionated concurrent chemoradiotherapy after induction chemo-immunotherapy i…
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CLINICAL_TRIALS research · 2025-07-20Clinical Trial Update: Tislelizumab Combined With Chemotherapy for Resectable Esophageal Squamous Cell Carcinoma Followed by CRT or Surgery [Phase 2]
Phase 2 clinical trial update for tislelizumab plus chemotherapy in resectable esophageal squamous cell carcinoma, followed by chemoradiothe…