Phase II Study of Hypofractionated Radiation Therapy to Augment Immune Response in Patients With Metastatic GastroIntestinal Malignancies Progressing on Immune Therapy (ARM-GI)

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Record identity and dates

Source

ClinicalTrials.gov

Source record ID

NCT04221893

Title field or adapter rule

protocolSection.identificationModule.officialTitle

Ingested At

2026-04-25T22:27:12.655298+00:00

Published At

2025-10-06T00:00:00+00:00

Record Updated At

2025-10-06

Timestamp Basis

source retrieval time was not retained by the feed adapter

Date limitation

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Fields recorded by this source

protocolSection.conditionsModule.conditions

["Stage IV Esophageal Adenocarcinoma", "Stage IV Esophageal Squamous Cell Carcinoma", "Stage IV Gastric Cancer", "Stage IV Adenocarcinoma of the Gastroesophageal Junction", "Stage IVA Esophageal Adenocarcinoma", "Stage IVA Esophageal Squamous Cell Carcinoma", "Stage IVA Gastric Cancer", "Stage IVA Adenocarcinoma of the Gastroesophageal Junction", "Stage IVB Esophageal Adenocarcinoma", "Stage IVB Esophageal Squamous Cell Carcinoma", "Stage IVB Gastric Cancer", "Stage IVB Gastroesophageal Junction Adenocarcinoma", "Metastatic Anal Canal Carcinoma", "Metastatic Colorectal Carcinoma", "Metastatic Esophageal Carcinoma", "Metastatic Gastric Carcinoma", "Metastatic Gastroesophageal Junction Adenocarcinoma", "Metastatic Hepatocellular Carcinoma", "Metastatic Malignant Digestive System Neoplasm", "Metastatic Small Intestinal Carcinoma", "Pancreatobiliary Carcinoma", "Pathologic Stage IV Gastric Cancer AJCC v8", "Pathologic Stage IVA Esophageal Adenocarcinoma AJCC v8", "Pathologic Stage IVA Esophageal Squamous Cell Carcinoma AJCC v8", "Pathologic Stage IVB Esophageal Adenocarcinoma AJCC v8", "Pathologic Stage IVB Esophageal Squamous Cell Carcinoma AJCC v8", "Pathologic Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8", "Postneoadjuvant Therapy Stage IV Esophageal Squamous Cell Carcinoma AJCC v8", "Postneoadjuvant Therapy Stage IV Gastric Cancer AJCC v8", "Postneoadjuvant Therapy Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8", "Postneoadjuvant Therapy Stage IVA Esophageal Adenocarcinoma AJCC v8", "Postneoadjuvant Therapy Stage IVA Esophageal Squamous Cell Carcinoma AJCC v8", "Postneoadjuvant Therapy Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8", "Postneoadjuvant Therapy Stage IVB Esophageal Adenocarcinoma AJCC v8", "Postneoadjuvant Therapy Stage IVB Esophageal Squamous Cell Carcinoma AJCC V8", "Postneoadjuvant Therapy Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8", "Stage IV Anal Cancer AJCC v8", "Stage IV Colorectal Cancer AJCC v8", "Stage IV Hepatocellular Carcinoma AJCC v8", "Stage IVA Colorectal Cancer AJCC v8", "Stage IVA Hepatocellular Carcinoma AJCC v8", "Stage IVB Colorectal Cancer AJCC v8", "Stage IVB Hepatocellular Carcinoma AJCC v8", "Stage IVC Colorectal Cancer AJCC v8"]

protocolSection.statusModule.lastUpdatePostDateStruct.date

"2025-10-06"

protocolSection.identificationModule.nctId

"NCT04221893"

protocolSection.identificationModule.officialTitle

"Phase II Study of Hypofractionated Radiation Therapy to Augment Immune Response in Patients With Metastatic GastroIntestinal Malignancies Progressing on Immune Therapy (ARM-GI)"

protocolSection.statusModule.overallStatus

"RECRUITING"

protocolSection.designModule.phases

["NA"]

protocolSection.statusModule.resultsFirstPostDateStruct.date

""

Study condition terms

• Stage IV Esophageal Adenocarcinoma (protocolSection.conditionsModule.conditions)
• Stage IV Esophageal Squamous Cell Carcinoma (protocolSection.conditionsModule.conditions)
• Stage IV Gastric Cancer (protocolSection.conditionsModule.conditions)
• Stage IV Adenocarcinoma of the Gastroesophageal Junction (protocolSection.conditionsModule.conditions)
• Stage IVA Esophageal Adenocarcinoma (protocolSection.conditionsModule.conditions)
• Stage IVA Esophageal Squamous Cell Carcinoma (protocolSection.conditionsModule.conditions)
• Stage IVA Gastric Cancer (protocolSection.conditionsModule.conditions)
• Stage IVA Adenocarcinoma of the Gastroesophageal Junction (protocolSection.conditionsModule.conditions)
• Stage IVB Esophageal Adenocarcinoma (protocolSection.conditionsModule.conditions)
• Stage IVB Esophageal Squamous Cell Carcinoma (protocolSection.conditionsModule.conditions)
• Stage IVB Gastric Cancer (protocolSection.conditionsModule.conditions)
• Stage IVB Gastroesophageal Junction Adenocarcinoma (protocolSection.conditionsModule.conditions)
• Metastatic Anal Canal Carcinoma (protocolSection.conditionsModule.conditions)
• Metastatic Colorectal Carcinoma (protocolSection.conditionsModule.conditions)
• Metastatic Esophageal Carcinoma (protocolSection.conditionsModule.conditions)
• Metastatic Gastric Carcinoma (protocolSection.conditionsModule.conditions)
• Metastatic Gastroesophageal Junction Adenocarcinoma (protocolSection.conditionsModule.conditions)
• Metastatic Hepatocellular Carcinoma (protocolSection.conditionsModule.conditions)
• Metastatic Malignant Digestive System Neoplasm (protocolSection.conditionsModule.conditions)
• Metastatic Small Intestinal Carcinoma (protocolSection.conditionsModule.conditions)
• Pancreatobiliary Carcinoma (protocolSection.conditionsModule.conditions)
• Pathologic Stage IV Gastric Cancer AJCC v8 (protocolSection.conditionsModule.conditions)
• Pathologic Stage IVA Esophageal Adenocarcinoma AJCC v8 (protocolSection.conditionsModule.conditions)
• Pathologic Stage IVA Esophageal Squamous Cell Carcinoma AJCC v8 (protocolSection.conditionsModule.conditions)
• Pathologic Stage IVB Esophageal Adenocarcinoma AJCC v8 (protocolSection.conditionsModule.conditions)
• Pathologic Stage IVB Esophageal Squamous Cell Carcinoma AJCC v8 (protocolSection.conditionsModule.conditions)
• Pathologic Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8 (protocolSection.conditionsModule.conditions)
• Postneoadjuvant Therapy Stage IV Esophageal Squamous Cell Carcinoma AJCC v8 (protocolSection.conditionsModule.conditions)
• Postneoadjuvant Therapy Stage IV Gastric Cancer AJCC v8 (protocolSection.conditionsModule.conditions)
• Postneoadjuvant Therapy Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 (protocolSection.conditionsModule.conditions)
• Postneoadjuvant Therapy Stage IVA Esophageal Adenocarcinoma AJCC v8 (protocolSection.conditionsModule.conditions)
• Postneoadjuvant Therapy Stage IVA Esophageal Squamous Cell Carcinoma AJCC v8 (protocolSection.conditionsModule.conditions)
• Postneoadjuvant Therapy Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8 (protocolSection.conditionsModule.conditions)
• Postneoadjuvant Therapy Stage IVB Esophageal Adenocarcinoma AJCC v8 (protocolSection.conditionsModule.conditions)
• Postneoadjuvant Therapy Stage IVB Esophageal Squamous Cell Carcinoma AJCC V8 (protocolSection.conditionsModule.conditions)
• Postneoadjuvant Therapy Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8 (protocolSection.conditionsModule.conditions)
• Stage IV Anal Cancer AJCC v8 (protocolSection.conditionsModule.conditions)
• Stage IV Colorectal Cancer AJCC v8 (protocolSection.conditionsModule.conditions)
• Stage IV Hepatocellular Carcinoma AJCC v8 (protocolSection.conditionsModule.conditions)
• Stage IVA Colorectal Cancer AJCC v8 (protocolSection.conditionsModule.conditions)
• Stage IVA Hepatocellular Carcinoma AJCC v8 (protocolSection.conditionsModule.conditions)
• Stage IVB Colorectal Cancer AJCC v8 (protocolSection.conditionsModule.conditions)
• Stage IVB Hepatocellular Carcinoma AJCC v8 (protocolSection.conditionsModule.conditions)
• Stage IVC Colorectal Cancer AJCC v8 (protocolSection.conditionsModule.conditions)

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