Esophageal Adenocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2024-02-13Clinical Trial Update: Nutritional Supplementation in Reducing Complications in Patients With Locally Advanced Esophageal Cancer Undergoing Chemotherapy, Radiation Therapy, and/or Surgery [Phase 3]
A Phase 3 trial evaluating nutritional supplementation to reduce complications in locally advanced esophageal cancer undergoing chemo/radiat…
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CLINICAL_TRIALS trial_result · 2024-01-18Clinical Trial Update: Use of Trifluridine/Tipiracil and Oxaliplatin as Induction Chemotherapy for the Treatment of Resectable Esophageal or Gastroesophageal Junction (GEJ) Adenocarcinoma [Phase 2]
Phase 2 trial evaluating induction chemotherapy with trifluridine/tipiracil and oxaliplatin for resectable esophageal or gastroesophageal ju…
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CLINICAL_TRIALS trial_result · 2024-01-08Clinical Trial Update: FOLFOX-6 Induction Chemotherapy Followed by Esophagectomy and Post-operative Chemoradiotherapy in Patients With Esophageal Adenocarcinoma [Phase 2]
Phase 2 clinical trial of FOLFOX-6 induction chemotherapy followed by esophagectomy and post-operative chemoradiotherapy for esophageal aden…
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CLINICAL_TRIALS trial_result · 2023-12-19Clinical Trial Update: Trial of mFOLFOX6 + Trastuzumab + Avelumab in Gastric and Esophageal Adenocarcinomas [Phase 2]
Phase 2 trial of mFOLFOX6 plus trastuzumab and avelumab in gastric and esophageal adenocarcinoma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-11-03Clinical Trial Update: Evaluate Esophageal Reinforcement With ACell MatriStem Surgical Matrix: A Degradable Biologic Scaffold Material [Phase 2]
Phase 2 clinical trial evaluating esophageal reinforcement using a degradable Biologic Scaffold (ACell MatriStem) for esophageal adenocarcin…
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CLINICAL_TRIALS trial_result · 2023-07-10Clinical Trial Update: Taladegib, Paclitaxel, Carboplatin, and Radiation Therapy in Treating Patients With Localized Esophageal or Gastroesophageal Junction Cancer [Phase 1, Phase 2]
Phase 1/2 trial investigating taladegib with paclitaxel, carboplatin, and radiation therapy for localized esophageal or gastroesophageal jun…
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CLINICAL_TRIALS trial_result · 2023-05-01Clinical Trial Update: Aspirin in Preventing Disease Recurrence in Patients With Barrett Esophagus After Successful Elimination by Radiofrequency Ablation [Phase 2]
A Phase 2 clinical trial investigates whether aspirin reduces recurrence of Barrett esophagus or progression to esophageal adenocarcinoma af…
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CLINICAL_TRIALS trial_result · 2023-02-01Clinical Trial Update: Rucaparib Plus Ramucirumab With or Without Nivolumab in Advanced Gastric and Esophageal Adenocarcinoma [Phase 1, Phase 2]
Clinical trial update for a combination therapy (rucaparib + ramucirumab with or without nivolumab) in advanced gastric and esophageal adeno…
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CLINICAL_TRIALS research · 2022-09-22Clinical Trial Update: Trial to Assess the Effects of an Antimicrobial Mouthwash on the Esophageal Microbiome [NA]
Completed clinical trial evaluating the effects of an antimicrobial mouthwash on the esophageal microbiome; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-06-30Clinical Trial Update: Pembrolizumab and Palliative Radiation Therapy in Treating Patients With Metastatic Esophagus, Stomach, or Gastroesophageal Junction Cancer [Phase 2]
A Phase 2 trial evaluating pembrolizumab combined with palliative radiation therapy in patients with metastatic cancers of the esophagus, st…
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CLINICAL_TRIALS trial_result · 2022-06-28Clinical Trial Update: Efficacy Study of Nivolumab Plus Ipilimumab or Nivolumab Plus Chemotherapy Against Chemotherapy in Stomach Cancer or Stomach/Esophagus Junction Cancer [Phase 3]
Phase 3 efficacy trial comparing nivolumab plus ipilimumab or nivolumab plus chemotherapy against standard chemotherapy in gastric cancer an…
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CLINICAL_TRIALS trial_result · 2022-06-24Clinical Trial Update: TRAstuzumab and Pertuzumab for HER2+ Resectable Oesophageal Cancer [Phase 3]
Phase 3 trial investigating trastuzumab and pertuzumab for HER2-positive resectable esophageal cancer (esophageal adenocarcinoma) is current…
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CLINICAL_TRIALS trial_result · 2021-10-01Clinical Trial Update: Study of Erlotinib and Chemotherapy for Unresectable or Metastatic Cancer of the Esophagus and Gastric Cardia [Phase 2]
Phase 2 clinical trial evaluating erlotinib with chemotherapy for unresectable or metastatic esophageal and gastric cardia adenocarcinoma co…
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CLINICAL_TRIALS trial_result · 2021-05-04Clinical Trial Update: Radiation Therapy, Paclitaxel, and Carboplatin With or Without Trastuzumab in Treating Patients With Esophageal Cancer [Phase 3]
Phase 3 trial evaluating radiation therapy with paclitaxel and carboplatin with or without trastuzumab in esophageal and gastroesophageal ju…
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CLINICAL_TRIALS trial_result · 2021-05-04Clinical Trial Update: Radiation Therapy, Paclitaxel, and Carboplatin With or Without Trastuzumab in Treating Patients With Esophageal Cancer [Phase 3]
Phase 3 trial evaluating radiation therapy with paclitaxel and carboplatin with or without trastuzumab in esophageal cancer (NCT01196390) ha…
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CLINICAL_TRIALS trial_result · 2021-04-21Clinical Trial Update: Chemoradiation and Panitumumab for Esophageal Cancer [Phase 2]
Phase 2 trial evaluating chemoradiation combined with panitumumab for esophageal cancer has completed.
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CLINICAL_TRIALS trial_result · 2021-04-19Clinical Trial Update: PDR001 Plus LAG525 for Patients With Advanced Solid and Hematologic Malignancies [Phase 2]
Phase 2 trial update evaluating PDR001 plus LAG525 in patients with advanced solid and hematologic malignancies; results posted with complet…
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CLINICAL_TRIALS trial_result · 2021-03-26Clinical Trial Update: Trial of S-1 Maintenance Therapy in Metastatic Esophagogastric Cancer [Phase 2]
Phase 2 trial evaluating S-1 maintenance therapy in unresectable, locally advanced or metastatic gastric/GEJ adenocarcinoma has been complet…
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CLINICAL_TRIALS trial_result · 2021-01-14Clinical Trial Update: Accuracy, Yield and Clinical Impact of a Low-Cost HRME in the Early Diagnosis of Esophageal Adenocarcinoma [Phase 2]
Phase 2 clinical trial update evaluating a low-cost HRME device for early diagnosis of esophageal adenocarcinoma in Barrett's Esophagus.
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CLINICAL_TRIALS trial_result · 2019-02-20Clinical Trial Update: Safety and Efficacy of CRS-207 With Pembrolizumab in Gastric, Gastroesophageal Junction or Esophageal Cancers [Phase 2]
Phase 2 trial assessing CRS-207 with pembrolizumab in gastric, gastroesophageal junction, and esophageal adenocarcinomas; study terminated w…
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CLINICAL_TRIALS trial_result · 2018-10-30Clinical Trial Update: Metabolomic and BH3 Profiling of Esophageal Cancers: Identification of Novel Assessment Methods of Treatment Response for Precision Therapy [Phase 2]
Phase 2 clinical trial exploring metabolomic and BH3 profiling to identify novel methods for assessing treatment response in esophageal canc…
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CLINICAL_TRIALS trial_result · 2018-10-17Clinical Trial Update: Regorafenib in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction Who Have Completed Chemoradiation Therapy and Surgery [Phase 2]
Phase 2 trial investigating regorafenib for locally advanced esophageal or gastroesophageal junction cancer after chemoradiation and surgery…
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CLINICAL_TRIALS trial_result · 2018-05-21Clinical Trial Update: Siewert Type I-II: CT, PET-CT, EUS Sensitivity/Specificity for the Assessment of Lymph Node Metastases
Completed clinical trial comparing CT, PET-CT, and EUS for detecting lymph node metastases in Siewert Type I-II esophageal/gastroesophageal …
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CLINICAL_TRIALS trial_result · 2018-03-22Clinical Trial Update: mDCF + Avelumab in Resectable Esophago-gastric Adenocarcinoma (EGA) [Phase 2]
Phase 2 trial update evaluating the combination of modified DCF chemotherapy (docetaxel, cisplatin, and 5-fluorouracil) with Avelumab in res…
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CLINICAL_TRIALS trial_result · 2018-03-09Clinical Trial Update: Study of Combination of Cetuximab and Radiotherapy Added to the Standard Treatment for Oesophageal Adenocarcinoma [Phase 2]
A Phase 2 trial evaluating the addition of cetuximab to radiotherapy and standard treatment for resectable esophageal adenocarcinoma has bee…