Esophageal Adenocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2025-02-06Clinical Trial Update: Molecular Analysis of Gastric and OEsophageal Cancers STudy
A molecular analysis study of gastric and esophageal cancers has been withdrawn from clinical trials.
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Tucatinib, Trastuzumab, Ramucirumab, and Paclitaxel Versus Paclitaxel and Ramucirumab in Previously Treated HER2+ Gastroesophageal Cancer [Phase 2, Phase 3]
Clinical trial update reporting results from a Phase 2/3 study of tucatinib + trastuzumab + ramucirumab + paclitaxel vs paclitaxel + ramucir…
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CLINICAL_TRIALS trial_result · 2025-01-16Clinical Trial Update: Study to Test the Safety and Tolerability of PF-07062119 in Patients With Selected Advanced or Metastatic Gastrointestinal Tumors. [Phase 1]
A Phase 1 study of PF-07062119 in selected advanced or metastatic gastrointestinal tumors was terminated, with results posted.
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CLINICAL_TRIALS research · 2024-11-15Clinical Trial Update: Study of Pembrolizumab (MK-3475) Versus Placebo in Participants With Esophageal Carcinoma Who Are Receiving Chemotherapy and Radiation Therapy (MK-3475-975/KEYNOTE-975) [Phase 3]
This is a Phase 3 trial (MK-3475-975/KEYNOTE-975) evaluating pembrolizumab versus placebo in combination with chemotherapy and radiotherapy …
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: Safety and Activity of IMAB362 in Combination With Zoledronic Acid and Interleukin-2 in CLDN18.2-positive Gastric Cancer [Phase 1]
Phase 1 study assessing safety and activity of IMAB362 (zolbetuximab) in combination with zoledronic acid and interleukin-2 in CLDN18.2-posi…
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: Oncometabolome and MALDI-MSI in Upper GI Carcinomas - Chemosensitivity in Esophageal Carcinoma
This clinical trial registry entry describes an exploratory study using oncometabolomics and MALDI-MSI to assess chemosensitivity in upper G…
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CLINICAL_TRIALS trial_result · 2024-11-08Clinical Trial Update: Rapid Assessment of Esophageal Adenocarcinoma Risk Test [NA]
A terminated Columbia University clinical trial evaluated a rapid risk-assessment test for esophageal adenocarcinoma in individuals with Bar…
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CLINICAL_TRIALS research · 2024-10-28Clinical Trial Update: Evaluate Mesothelin as a Biomarker for the Clinical Management of Esophageal Adenocarcinoma (EAC)
A completed clinical trial evaluated mesothelin as a biomarker for the clinical management of esophageal adenocarcinoma.
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CLINICAL_TRIALS research · 2024-10-24Clinical Trial Update: Oxaliplatin ± Nivolumab in Combination With Trifluridine/Tipiracil or 5-fluorouracile in Frail Patients With Advanced, Recurrent or Metastatic Gastric, Oesophageal or Gastroesophageal Junction Cancer [Phase 2]
Phase 2 trial assessing oxaliplatin with or without nivolumab in combination with trifluridine/tipiracil or 5-fluorouracil for frail patient…
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CLINICAL_TRIALS trial_result · 2024-10-23Clinical Trial Update: Study of INBRX-105 and INBRX-105 With Pembrolizumab in Patients With Solid Tumors Including Head and Neck Cancer [Phase 1]
This Phase 1 trial update reports termination of the INBRX-105 in combination with pembrolizumab across multiple solid tumors, including hea…
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CLINICAL_TRIALS trial_result · 2024-10-02Clinical Trial Update: Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT141 in Patients With Unresectable or Metastatic CLDN18.2-positive Gastric, Pancreatic, Ovarian and Biliary Tract Tumors [Phase 1, Phase 2]
Phase 1/2 trial of BNT141 in CLDN18.2-positive gastric, pancreatic, ovarian, and biliary tract cancers. The study was terminated and results…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Organ Preservation With Durvalumab-based Immunotherapy in Combination With Chemoradiation as Definitive Therapy for Early Stage Esophageal Adenocarcinoma With Indication for Radical Surgery [Phase 2]
Phase 2 clinical trial evaluating organ preservation with durvalumab-based immunotherapy in combination with chemoradiation as definitive tr…
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CLINICAL_TRIALS trial_result · 2024-08-16Clinical Trial Update: NT-I7 in Combination With Nivolumab in Advanced Gastric, Gastro-Esophageal Junction or Esophageal Adenocarcinoma [Phase 1]
A Phase 1 trial of NT-I7 in combination with nivolumab for advanced gastric, gastroesophageal junction, or esophageal adenocarcinoma has bee…
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CLINICAL_TRIALS research · 2024-08-02Clinical Trial Update: Anti-PD-1 and CapOx for the First-line Treatment of dMMR Esophagogastric Cancer (AuspiCiOus) [Phase 2]
Phase 2 clinical trial evaluating a PD-1 inhibitor with Capecitabine and Oxaliplatin (CapOx) as first-line therapy for dMMR esophagogastric …
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CLINICAL_TRIALS research · 2024-07-29Clinical Trial Update: Blood-borne Assessment of Stromal Activation in Esophageal Adenocarcinoma to Guide Tocilizumab Therapy [Phase 2]
A Phase 2 clinical trial update investigating whether blood-based stromal activation biomarkers can guide tocilizumab therapy in esophageal …
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CLINICAL_TRIALS research · 2024-07-24Clinical Trial Update: Prospective Endoscopic Follow-up of Patients With Submucosal and High Risk Mucosal Esophageal Adenocarcinoma [NA]
This trial is an ongoing prospective endoscopic follow-up study of patients with submucosal or high-risk mucosal esophageal adenocarcinoma a…
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CLINICAL_TRIALS trial_result · 2024-07-18Clinical Trial Update: M6620 Plus Standard Treatment in Oesophageal and Other Cancer [Phase 1]
Phase 1 trial evaluating M6620 in combination with standard treatment for esophageal cancer (esophageal adenocarcinoma and esophageal squamo…
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CLINICAL_TRIALS research · 2024-07-17Clinical Trial Update: Barrett's Esophagus and Esophageal Adenocarcinoma, Searching for Reliable Diagnostic RNA Plasma-based Biomarkers
A clinical trial aims to identify plasma RNA biomarkers to help diagnose Barrett's esophagus and esophageal adenocarcinoma, and it is curren…
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CLINICAL_TRIALS research · 2024-06-12Clinical Trial Update: Seattle Biopsy Protocol Versus Wide-Area Transepithelial Sampling in Patients With Barrett's Esophagus Undergoing Surveillance [NA]
A clinical trial update shows ongoing recruitment for a study comparing the Seattle biopsy protocol versus Wide-Area Transepithelial Samplin…
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CLINICAL_TRIALS trial_result · 2024-05-20Clinical Trial Update: Phase II Trial of Neoadjuvant Pembrolizumab for Patients With Early Stage Gastroesophageal Adenocarcinoma [Phase 2]
Phase II neoadjuvant pembrolizumab trial for early-stage gastroesophageal junction, gastric, and esophageal adenocarcinoma has been terminat…
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CLINICAL_TRIALS trial_result · 2024-05-10Clinical Trial Update: A Liquid Biopsy for High-risk Pre-cancer Screening of Esophageal Adenocarcinoma
This clinical trial evaluating a liquid biopsy for high-risk pre-cancer screening of esophageal adenocarcinoma has completed.
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CLINICAL_TRIALS research · 2024-05-09Clinical Trial Update: RICE: Radio-Immuno-Chemotherapy of Cancer of the Esophagus [Phase 2]
Phase 2 clinical trial update on RICE (Radio-Immuno-Chemotherapy) for esophageal adenocarcinoma; current status is unknown.
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Perioperative Chemotherapy Compared To Neoadjuvant Chemoradiation in Patients With Adenocarcinoma of the Esophagus [Phase 3]
This clinical trial update describes a Phase 3 study comparing perioperative chemotherapy to neoadjuvant chemoradiation for esophageal adeno…
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: Study of Pembrolizumab in Locally Advanced Esophageal Adenocarcinoma [Phase 2]
A Phase 2 clinical trial evaluating pembrolizumab in locally advanced esophageal adenocarcinoma has posted results.
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CLINICAL_TRIALS trial_result · 2024-03-15Clinical Trial Update: Multiorgan Metabolic Imaging Response Assessment of Abemaciclib [Phase 2]
Phase 2 trial update evaluating multiorgan metabolic imaging response assessment of abemaciclib.