Esophageal Adenocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-07-22Clinical Trial Update: Study of Pembrolizumab (MK-3475) Versus Placebo in Participants With Esophageal Carcinoma Who Are Receiving Chemotherapy and Radiation Therapy (MK-3475-975/KEYNOTE-975) [Phase 3]
Phase 3 trial examining pembrolizumab plus chemoradiation versus placebo in esophageal cancer has completed.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies [Phase 2]
Phase 2 clinical trial evaluating a PD-1–blocking monoclonal antibody in combination with a metabolic modulator for several solid tumors is …
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Study of Suratadenoturev (OBP-301) in Combination With Pembrolizumab in Esophagogastric Adenocarcinoma [Phase 2]
Phase 2 trial evaluating Suratadenoturev (OBP-301) in combination with pembrolizumab for esophagogastric adenocarcinoma; recruitment is ongo…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Study of Denikitug (GS-1811) Given Alone or With Nivolumab or Chemotherapy in Adults With Metastatic Gastric, Gastroesophageal Junction (GEJ), and Esophageal Adenocarcinomas [Phase 2]
Phase 2 clinical trial evaluating Denikitug (GS-1811) alone or with nivolumab or chemotherapy in adults with metastatic gastric, gastroesoph…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancers [Phase 1]
This update details a Phase 1 study evaluating DISP-10 in advanced gastrointestinal cancers, with the trial currently not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Adjuvant Trastuzumab Deruxtecan (Enhertu) & Nivolumab For Patients Who Are Disease Free After Completion of Trimodality Treatment For HER-2+ Cancers of Esophagus & Gastroesophageal Junction [Phase 2]
This clinical trial update notes a Phase 2 study of adjuvant trastuzumab deruxtecan (Enhertu) in combination with nivolumab for patients who…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial is evaluating nivolumab added to standard therapy for advanced gastric and esophageal adenocarcinomas, incl…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: A Study of Sigvotatug Vedotin in Advanced Solid Tumors [Phase 1]
Phase 1 study of Sigvotatug Vedotin in advanced solid tumors is currently recruiting. The trial targets multiple indications, including non-…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Preoperative Hypofractionated Radiotherapy With FOLFOX for Esophageal or Gastroesophageal Junction Adenocarcinoma [Phase 2]
A Phase 2 clinical trial evaluating preoperative hypofractionated radiotherapy in combination with the FOLFOX regimen for esophageal or gast…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers [Phase 3]
Phase 3 clinical trial update for zanidatamab in combination with chemotherapy with or without tislelizumab in HER2-positive advanced or met…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Minimally Invasive Approaches for the Diagnosis of Barrett's Esophagus and Esophageal Cancer, SOS5C Trial [NA]
A Mayo Clinic-sponsored SOS5C clinical trial is evaluating minimally invasive diagnostic approaches for Barrett's esophagus and esophageal a…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Minimally Invasive Molecular Approaches for the Detection of Barrett's Esophagus- High Grade Dysplasia and Esophageal Adenocarcinoma
A Mayo Clinic–sponsored clinical trial update describing an ongoing study of minimally invasive molecular approaches to detect Barrett's eso…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: NBTXR3, Chemotherapy, and Radiation Therapy for the Treatment of Esophageal Cancer [Phase 1]
Phase 1 trial evaluating NBTXR3 in combination with chemotherapy and radiation therapy for esophageal cancer; recruitment is ongoing across …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread [Phase 1, Phase 2]
A Phase 1/2 trial evaluating the dose of Zongertinib used alone or with other therapies in HER2-positive metastatic cancers, including breas…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of BL-M05D1 in Subjects With Solid Tumors [Phase 1]
An ongoing Phase 1 trial is evaluating BL-M05D1 in patients with solid tumors, assessing safety, tolerability, pharmacokinetics, and prelimi…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Cryotherapy for Malignant Dysphagia in Patients With Advanced Esophageal Cancer [NA]
This clinical trial update reports the completion of a study evaluating cryotherapy for malignant dysphagia in patients with advanced esopha…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2 [Phase 3]
Phase 3 trial evaluating Sonesitatug Vedotin with Capecitabine, with or without Rilvegostomig, in advanced or metastatic Claudin18.2-express…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors [Phase 1]
Plexium, Inc. is conducting a first-in-human Phase 1 study of PLX-61639 in locally advanced or metastatic solid tumors, and the trial is cur…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Obeticholic Acid for Prevention in Barrett's Esophagus [Phase 2]
A Phase 2 clinical trial is evaluating obeticholic acid for prevention in Barrett's Esophagus, with recruitment ongoing and potential releva…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery [Phase 2, Phase 3]
A phase 2/3 trial of Nivolumab and Ipilimumab in esophageal and gastroesophageal junction adenocarcinoma undergoing surgery is currently sus…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Oral Bevacizumab-800CW and Cetuximab-800CW Administration to Detect Early Esophageal Adenocarcinomas [Phase 2]
A Phase 2 clinical trial evaluating oral Bevacizumab-800CW and Cetuximab-800CW as imaging agents to detect early esophageal adenocarcinomas …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Itraconazole in Combination With Ablation for the Prevention of Esophageal Cancer in Patients With High-risk Barrett's Esophagus [Phase 2]
A Phase 2 clinical trial evaluates itraconazole in combination with ablation to prevent progression to esophageal cancer in patients with hi…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer [Phase 2, Phase 3]
Pfizer is enrolling patients in a Phase 2/Phase 3 study testing PF-08634404 with chemotherapy for untreated advanced or metastatic gastric c…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Clinical Study of Regorafenib and Nivolumab Plus Chemotherapy [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical study of regorafenib and nivolumab plus chemotherapy for gastric and gastroesophageal junction adenocarcinoma (an…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Phase 2 Futibatinib in Combination With PD-1 Antibody Based Standard of Care in Solid Tumors [Phase 2]
Phase 2 study evaluating futibatinib in combination with a PD-1 antibody-based standard of care for locally advanced unresectable or metasta…