Esophageal Adenocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Multicenter Prospective Cohort on Esophageal Endoscopic Submucosal Dissection
A multicenter prospective cohort study evaluating esophageal endoscopic submucosal dissection for superficial esophageal cancer and Barrett'…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Neoadjuvant Intra-tumoral RP2 and FLOT in Gastroesophageal Adenocarcinoma [Phase 2]
A Phase 2 neoadjuvant trial evaluating intra-tumoral RP2 in combination with the FLOT regimen for gastric and esophageal adenocarcinoma is l…
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: Propranolol With Standard Chemoradiation for Esophageal Adenocarcinoma [Phase 2]
A Phase 2 trial is examining propranolol in combination with standard chemoradiation for esophageal adenocarcinoma, currently in recruitment…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: A Phase Ib Trial Evaluating the Safety and Activity of Neoadjuvant Combination of Tislelizumab Plus FLOT for Resectable Esophagogastric Adenocarcinoma [Phase 1]
Phase Ib trial evaluating the safety and activity of neoadjuvant tislelizumab plus the FLOT chemotherapy regimen in patients with resectable…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Assessment of a Minimally Invasive Collection Device for Molecular Analysis of Esophageal Samples [NA]
This ClinicalTrials.gov update describes a minimally invasive collection device designed for molecular analysis of esophageal samples, with …
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Propranolol in Combination With Pembrolizumab and Standard Chemotherapy for the Treatment of Unresectable Locally Advanced or Metastatic Esophageal or Gastroesophageal Junction Adenocarcinoma [Phase 2]
Phase 2 clinical trial evaluating propranolol in combination with pembrolizumab and standard chemotherapy for unresectable or metastatic eso…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Barrett's Esophagitis in Anorexia Nervosa Binge/Purge Subtype
Clinical trial update examining Barrett's esophagus in individuals with anorexia nervosa binge/purge subtype; the study is currently recruit…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: AUGMENTED RESPONSE OF VOLATILE BIOMARKERS IN THE ASSESSMENT OF OESOPHAGOGASTRIC CANCER (AROMA2)
A ClinicalTrials.gov entry for the AROMA2 study examines whether volatile biomarker profiles can augment assessment of esophagogastric cance…
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CLINICAL_TRIALS research · 2025-11-28Clinical Trial Update: Testing Ivonescimab in Combination With Chemotherapy in Advanced or Metastatic Gastric/Gastroesophageal Adenocarcinoma [Phase 2]
Phase 2 clinical trial evaluating Ivonescimab in combination with chemotherapy for advanced or metastatic gastric/gastroesophageal adenocarc…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Surveillance vs. Endoscopic Therapy for Barrett's Esophagus With Low-grade Dysplasia [NA]
An ongoing clinical trial comparing surveillance versus endoscopic therapy for Barrett's esophagus with low-grade dysplasia. The study is cu…
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CLINICAL_TRIALS research · 2025-11-13Clinical Trial Update: Multi-Site Detection of Barrett's Esophagus in Patients Without Chronic GERD Symptoms [NA]
A multi-site clinical trial is investigating detection of Barrett's esophagus in patients without chronic GERD symptoms; recruitment is ongo…
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CLINICAL_TRIALS research · 2025-10-31Clinical Trial Update: Liquid Nitrogen Spray Cryotherapy Prior to Neoadjuvant Systemic Therapy in Esophageal Adenocarcinoma [Phase 2]
A Phase 2 clinical trial evaluating liquid nitrogen spray cryotherapy before neoadjuvant systemic therapy for esophageal adenocarcinoma; the…
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CLINICAL_TRIALS research · 2025-10-06Clinical Trial Update: Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers [NA]
A UCSF-led clinical trial is evaluating radiation therapy for metastatic gastrointestinal cancers, and the study is currently recruiting.
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: "Less-is-more in Barrett-surveillance" Care Evaluation of Barrett's Patients With Low-Risk in Whom Endoscopic Surveillance is Stopped. The BLISS Project.
An Amsterdam-based study (BLISS Project) is evaluating whether endoscopic surveillance can be stopped in low-risk Barrett's esophagus patien…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Evaluation of Seismocardiography(SCG) for Assessing Fitness and Predicting Outcomes in Oesophageal Cancer Surgery
The document describes a non-recruiting clinical trial evaluating seismocardiography to assess fitness and predict outcomes in esophageal ca…
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: Chemoradiation and Pembrolizumab Followed by Pembrolizumab and Lenvatinib Before Surgery for the Treatment of Non-metastatic Esophageal or Esophageal/Gastroesophageal Junction Cancer [Phase 2]
A Phase 2 clinical trial update evaluating chemoradiation with pembrolizumab, followed by pembrolizumab and lenvatinib before surgery for no…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: A Vaccine (Ad5.F35-hGCC-PADRE) for the Treatment of Gastrointestinal Adenocarcinoma [Phase 2]
Phase 2 clinical trial update on the Ad5.F35-hGCC-PADRE cancer vaccine for pancreatic, colorectal, gastric, and esophageal adenocarcinomas; …
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: Outcomes of a Single Chest Drain vs Two Drains [NA]
A clinical trial comparing single chest drain versus two drains in patients with pleural effusion and esophageal cancer-related complication…
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma
A Case Western Reserve University-led study aims to identify genetic determinants of Barrett's Esophagus and esophageal adenocarcinoma and i…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Metformin as a Metabolic Intervention in Oesophageal Adenocarcinomas to Improve Response to Neoadjuvant Chemoradiotherapy [Phase 2]
A Phase 2 clinical trial is evaluating metformin as a metabolic intervention to improve response to neoadjuvant chemoradiotherapy in esophag…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Planning Treatment for Oesophago-gastric Cancer: a Maintenance Therapy Trial [Phase 2]
A Phase 2 maintenance therapy trial for oesophago-gastric cancer is active but not recruiting, focusing on esophageal, gastroesophageal junc…
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Oral TGF-beta Receptor I Inhibitor Vactosertib in SOC Chemoradiotherapy for Esophageal Adenocarcinoma [Phase 2]
Phase 2 trial evaluating the TGF-beta receptor I inhibitor Vactosertib in combination with standard-of-care chemoradiotherapy for locally ad…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: Longitudinal Assessment of Biomarkers After Oesophagogastric Cancer Surgery
A longitudinal biomarker study in patients undergoing esophageal/gastric cancer surgery. Imperial College London is recruiting to profile bi…
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CLINICAL_TRIALS research · 2024-11-15Clinical Trial Update: Study of Pembrolizumab (MK-3475) Versus Placebo in Participants With Esophageal Carcinoma Who Are Receiving Chemotherapy and Radiation Therapy (MK-3475-975/KEYNOTE-975) [Phase 3]
This is a Phase 3 trial (MK-3475-975/KEYNOTE-975) evaluating pembrolizumab versus placebo in combination with chemotherapy and radiotherapy …
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: Oncometabolome and MALDI-MSI in Upper GI Carcinomas - Chemosensitivity in Esophageal Carcinoma
This clinical trial registry entry describes an exploratory study using oncometabolomics and MALDI-MSI to assess chemosensitivity in upper G…