Epithelioid Sarcoma

• CLINICAL_TRIALS trial_result · 2026-04-13
  Clinical Trial Update: Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient Tumors [Phase 1, Phase 2]

  Clinical trial update of a tiragolumab plus atezolizumab combination for relapsed or refractory SMARCB1/SMARCA4-deficient tumors, spanning P…

• CLINICAL_TRIALS trial_result · 2026-03-31
  Clinical Trial Update: Compassionate Use of Ubamatamab

  The document notes compassionate-use access to Ubamatamab for renal medullary carcinoma and epithelioid sarcoma, sponsored by Regeneron, wit…

• CLINICAL_TRIALS trial_result · 2026-03-06
  Clinical Trial Update: Prospective Identification of Predictive Biomarkers of Trabectedin Efficacy in Non-L Soft-tissue Sarcoma Patients [NA]

  Trial update reporting prospective identification of predictive biomarkers for trabectedin efficacy across non-liposarcoma soft tissue sarco…

• CLINICAL_TRIALS trial_result · 2026-01-07
  Clinical Trial Update: Tazemetostat in Combination With Doxorubicin as Frontline Therapy for Advanced Epithelioid Sarcoma [Phase 1]

  A Phase 1 trial evaluating tazemetostat with doxorubicin as frontline therapy for advanced epithelioid sarcoma has been terminated.

• CLINICAL_TRIALS trial_result · 2025-11-04
  Clinical Trial Update: A Study to Assess Long-term Safety of Tazemetostat in Adult Participants of All Ages With Any Disease Treated With Tazemetostat in a Previous Clinical Study [Phase 1, Phase 2]

  This document reports the completion of a long-term safety study of tazemetostat in adults who previously received the drug in earlier trial…

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• CLINICAL_TRIALS trial_result · 2025-10-29
  Clinical Trial Update: A Study of Talimogene Laherparepvec (T-VEC) in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced Sarcoma [Phase 2]

  Phase 2 study of talimogene laherparepvec (T-VEC) in combination with pembrolizumab in metastatic and/or locally advanced sarcoma reports re…

• CLINICAL_TRIALS trial_result · 2025-03-11
  Clinical Trial Update: A Study of Tazemetostat in Adult Participants With Soft Tissue Sarcoma [Phase 2]

  Phase 2 study of tazemetostat in adult participants with soft tissue sarcoma, including rhabdoid tumors, has completed and results were post…

• CLINICAL_TRIALS trial_result · 2025-02-17
  Clinical Trial Update: Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers [Phase 1, Phase 2]

  Phase 1/2 trial update evaluating nivolumab plus ABI-009 (nab-rapamycin) in patients with advanced sarcoma and selected cancers, with result…

• CLINICAL_TRIALS trial_result · 2024-10-01
  Clinical Trial Update: Tazemetostat Expanded Access Program for Adults With Epithelioid Sarcoma

  The expanded access program for tazemetostat in adults with epithelioid sarcoma is no longer available.

• CLINICAL_TRIALS trial_result · 2024-08-26
  Clinical Trial Update: Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels [Phase 1]

  Phase 1 trial assessing the pharmacokinetic interactions of itraconazole and rifampin with tazemetostat; results published for patients with…

• CLINICAL_TRIALS trial_result · 2023-11-07
  Clinical Trial Update: Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma [Phase 2]

  Phase 2 trial evaluating doxorubicin with upfront dexrazoxane for advanced or metastatic soft tissue sarcoma has completed enrollment with r…

• CLINICAL_TRIALS trial_result · 2018-11-23
  Clinical Trial Update: Trial of Dasatinib in Advanced Sarcomas [Phase 2]

  Phase 2 trial update for dasatinib in advanced sarcomas, with completed status and results posted in 2018.

• CLINICAL_TRIALS trial_result · 2017-05-12
  Clinical Trial Update: Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue Sarcoma [Phase 2]

  Phase 2 clinical trial update for romidepsin (depsipeptide) in patients with metastatic or unresectable soft tissue sarcoma, with results po…

• CLINICAL_TRIALS trial_result · 2016-05-17
  Clinical Trial Update: Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue Sarcoma [Phase 1]

  This Phase 1 trial evaluated the combination of cixutumumab and doxorubicin in patients with unresectable, locally advanced, or metastatic s…

• CLINICAL_TRIALS trial_result · 2014-01-20
  Clinical Trial Update: Sorafenib in Treating Patients With Metastatic, Locally Advanced, or Recurrent Sarcoma [Phase 2]

  Phase 2 clinical trial evaluating sorafenib for metastatic, locally advanced, or recurrent sarcoma has completed and posted results in 2014.