Epithelioid Sarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Tazemetostat+Nivo/Ipi in INI1-Neg/SMARCA4-Def Tumors [Phase 1, Phase 2]
A clinical trial update on a Phase 1/2 study of combining tazemetostat with nivolumab and ipilimumab in INI1/SMARCB1-deficient and SMARCA4-d…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient Tumors [Phase 1, Phase 2]
Clinical trial update of a tiragolumab plus atezolizumab combination for relapsed or refractory SMARCB1/SMARCA4-deficient tumors, spanning P…
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Compassionate Use of Ubamatamab
The document notes compassionate-use access to Ubamatamab for renal medullary carcinoma and epithelioid sarcoma, sponsored by Regeneron, wit…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Prospective Identification of Predictive Biomarkers of Trabectedin Efficacy in Non-L Soft-tissue Sarcoma Patients [NA]
Trial update reporting prospective identification of predictive biomarkers for trabectedin efficacy across non-liposarcoma soft tissue sarco…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Multimodal Immune Characterization of RAre Soft Tissue Sarcoma - MIRAS Project From SARRA (SARcome RAre) Project of the French Sarcoma Group [NA]
An ongoing clinical trial under the MIRAS project aims to perform multimodal immune characterization of rare soft tissue sarcomas and relate…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Evaluate the Safety and Clinical Activity of HH2853 [Phase 1, Phase 2]
The trial update indicates HH2853 is being studied in Phase 1/Phase 2 across follicular lymphoma, epithelioid sarcoma, peripheral T-cell lym…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: Tazemetostat in Combination With Doxorubicin as Frontline Therapy for Advanced Epithelioid Sarcoma [Phase 1]
A Phase 1 trial evaluating tazemetostat with doxorubicin as frontline therapy for advanced epithelioid sarcoma has been terminated.
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers [Phase 2]
This update describes a Phase 2 study of the combination of nivolumab and ipilimumab in children and young adults with INI1-negative cancers…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: An Observational Study on Epithelioid Sarcoma
An observational clinical trial studying epithelioid sarcoma is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-11-04Clinical Trial Update: A Study to Assess Long-term Safety of Tazemetostat in Adult Participants of All Ages With Any Disease Treated With Tazemetostat in a Previous Clinical Study [Phase 1, Phase 2]
This document reports the completion of a long-term safety study of tazemetostat in adults who previously received the drug in earlier trial…
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CLINICAL_TRIALS trial_result · 2025-10-29Clinical Trial Update: A Study of Talimogene Laherparepvec (T-VEC) in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced Sarcoma [Phase 2]
Phase 2 study of talimogene laherparepvec (T-VEC) in combination with pembrolizumab in metastatic and/or locally advanced sarcoma reports re…
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue Sarcoma [Phase 2]
A Phase 2 trial evaluating MASCT-I in combination with doxorubicin and ifosfamide as first-line therapy for advanced soft tissue sarcoma is …
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CLINICAL_TRIALS trial_result · 2025-03-11Clinical Trial Update: A Study of Tazemetostat in Adult Participants With Soft Tissue Sarcoma [Phase 2]
Phase 2 study of tazemetostat in adult participants with soft tissue sarcoma, including rhabdoid tumors, has completed and results were post…
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers [Phase 1, Phase 2]
Phase 1/2 trial update evaluating nivolumab plus ABI-009 (nab-rapamycin) in patients with advanced sarcoma and selected cancers, with result…
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: Tazemetostat Expanded Access Program for Adults With Epithelioid Sarcoma
The expanded access program for tazemetostat in adults with epithelioid sarcoma is no longer available.
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CLINICAL_TRIALS trial_result · 2024-08-26Clinical Trial Update: Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels [Phase 1]
Phase 1 trial assessing the pharmacokinetic interactions of itraconazole and rifampin with tazemetostat; results published for patients with…
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CLINICAL_TRIALS trial_result · 2023-11-07Clinical Trial Update: Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma [Phase 2]
Phase 2 trial evaluating doxorubicin with upfront dexrazoxane for advanced or metastatic soft tissue sarcoma has completed enrollment with r…
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FDA approval · 2020-01-23FDA Approved: TAZVERIK — Original Application (Epizyme, Inc.)
The FDA approved the original application for TAZVERIK (tazemetostat) by Epizyme, Inc. for epithelioid sarcoma, marking the first approved i…
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CLINICAL_TRIALS trial_result · 2018-11-23Clinical Trial Update: Trial of Dasatinib in Advanced Sarcomas [Phase 2]
Phase 2 trial update for dasatinib in advanced sarcomas, with completed status and results posted in 2018.
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CLINICAL_TRIALS trial_result · 2017-05-12Clinical Trial Update: Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue Sarcoma [Phase 2]
Phase 2 clinical trial update for romidepsin (depsipeptide) in patients with metastatic or unresectable soft tissue sarcoma, with results po…
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CLINICAL_TRIALS trial_result · 2016-05-17Clinical Trial Update: Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue Sarcoma [Phase 1]
This Phase 1 trial evaluated the combination of cixutumumab and doxorubicin in patients with unresectable, locally advanced, or metastatic s…
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CLINICAL_TRIALS research · 2016-05-17Clinical Trial Update: Studying Genes in Tissue Samples From Younger and Adolescent Patients With Soft Tissue Sarcomas
A completed clinical trial update studying gene expression in tissue samples from children and adolescents with soft tissue sarcomas to bett…
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CLINICAL_TRIALS trial_result · 2014-01-20Clinical Trial Update: Sorafenib in Treating Patients With Metastatic, Locally Advanced, or Recurrent Sarcoma [Phase 2]
Phase 2 clinical trial evaluating sorafenib for metastatic, locally advanced, or recurrent sarcoma has completed and posted results in 2014.