Clinical Trial Update: Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels [Phase 1]

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Summary

Phase 1 trial assessing the pharmacokinetic interactions of itraconazole and rifampin with tazemetostat; results published for patients with various malignancie…

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Diseases / indications

• Diffuse Large B-cell Lymphoma
• Epithelioid Sarcoma
• Follicular Lymphoma
• Mesothelioma
• Non-hodgkin Lymphoma
• Renal Medullary Carcinoma
• Rhabdoid Tumor
• Synovial Sarcoma

Drugs mentioned

• Rifadin (rifampin)
• SPORANOX (Itraconazole)
• TAZVERIK (TAZEMETOSTAT)

Snippet

Sponsor: Epizyme, Inc. | Conditions: All Malignancies, Advanced Malignancies | Phase 1 | Status: COMPLETED | Results posted: 2024-08-26