Drug-induced Liver Injury
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Drug-Induced Liver Injury (DILI) Network Retrospective
Duke University sponsors a clinical trial investigating drug-induced liver injury (DILI) through a retrospective network; the study is curre…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: DILIN - Prospective Study
A prospective DILI study run by the Drug-Induced Liver Injury Network (DILIN), sponsored by Duke University, is currently in recruitment.
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: A Real World Study of Polyene Phosphatidylcholine Injection for the Prevention and Treatment of DILI in Patients With Malignant Hematological Diseases
A real-world study is evaluating polyene phosphatidylcholine injections for prevention and treatment of drug-induced liver injury in patient…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: miroliverELAP® for the Treatment of Acute Liver Failure: A Phase 1 Trial [Phase 1]
Phase 1 trial of miroliverELAP for acute liver failure has been completed. The document provides an update on the trial status by Miromatrix…
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: Impact of Silymarin Dosages to Decrease Drug-induced Elevated Liver Enzymes Compared to Placebo [Phase 2, Phase 3]
A completed Phase 2/3 clinical trial evaluating different silymarin dosages versus placebo for lowering elevated liver enzymes in drug-induc…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Glucocorticoids for Acute Drug Induced Liver Injury With Hyperbilirubinemia [NA]
This clinical trial update notes a recruiting study evaluating glucocorticoids for acute drug-induced liver injury with hyperbilirubinemia.
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CLINICAL_TRIALS trial_result · 2025-11-25Clinical Trial Update: Evaluation of the Efficacy of Fomepizole in the Treatment of Acetaminophen Overdose [Phase 2]
A Phase 2 trial evaluating fomepizole for acetaminophen overdose was terminated; no efficacy results are reported.
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CLINICAL_TRIALS trial_result · 2025-10-09Clinical Trial Update: Digoxin In Treatment of Alcohol Associated Hepatitis [Phase 2]
Phase 2 trial of digoxin in Acute Alcoholic Hepatitis was terminated; no efficacy or safety results are provided in this update.
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: A Prognostic Model for Drug-induced Liver Injury in China
This clinical trial from Beijing Friendship Hospital is developing a prognostic model to predict drug-induced liver injury in China. The stu…
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CLINICAL_TRIALS trial_result · 2025-08-13Clinical Trial Update: Remaxol® in Patients With Drug-induced Liver Injuries During Cancer Chemotherapy
Remaxol® was studied for drug-induced liver injuries in cancer patients receiving chemotherapy; the clinical trial has completed.
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CLINICAL_TRIALS trial_result · 2025-07-31Clinical Trial Update: Clinical Study to Evaluate Cannabidiol Liver Enzyme Elevations and Drug Interactions [Phase 1]
A Phase 1 FDA-sponsored study evaluating cannabidiol's effects on liver enzymes and potential drug interactions has completed, with results …
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Comparison of the Outcome of Treatment With Silymarin or N-Aceylcysteine in Patients Taking Anti-Tuberculous Drugs for Tuberculosis at a Tertiary Care Hospital , Karachi [Phase 1]
Phase 1 clinical trial at a tertiary care hospital comparing silymarin versus N-acetylcysteine for preventing or reducing drug-induced liver…
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: Drug-induced Liver Injury: Itching Study
A clinical trial from the University of Nottingham is currently recruiting to study drug-induced liver injury and pruritus (itching).
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: A Retrospective Study in Patients With Liver Injury After the Use of Novel Antineoplastic Agents
This retrospective study examines liver injury in patients treated with novel antineoplastic agents. The study is currently active but not r…
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: A Prospective Cohort Study on Drug-induced Liver Injury in China（DILI-P）
A prospective cohort study in China (DILI-P) is currently recruiting to investigate drug-induced liver injury (DILI).
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: Role of N-Acetylcysteine in Non-Acetaminophen-Induced Acute Liver Failure [NA]
Clinical trial investigating N-acetylcysteine for non-acetaminophen-induced acute liver failure; status is active but not recruiting.
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CLINICAL_TRIALS research · 2025-02-26Clinical Trial Update: Screening of Susceptibility Genes for APAP Induced Drug Induced LIver Injury in ChiNese Population: a Case-control Study
An ongoing case-control study in China is screening genetic susceptibility genes for acetaminophen-induced drug-induced liver injury.
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Efficacy of Plasmapheresis in Patients of Drug-Induced Liver Injury (DILI) With Underlying Chronic Liver Disease [Phase 2, Phase 3]
A Phase 2/3 clinical trial update evaluating plasmapheresis for drug-induced liver injury in patients with chronic liver disease, currently …
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CLINICAL_TRIALS research · 2025-01-13Clinical Trial Update: Prospective Comparative Validation Study of RUCAM and RECAM
This clinical trial update outlines a prospective comparative validation study of RUCAM and RECAM for drug-induced liver injury, currently r…
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CLINICAL_TRIALS research · 2024-08-12Clinical Trial Update: Clinicopathological Features and Genetic Susceptibility Screening of Recurrent Drug-induced Liver Injury
The entry reports an ongoing clinical trial evaluating clinicopathological features and genetic susceptibility screening for recurrent drug-…
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CLINICAL_TRIALS trial_result · 2024-05-21Clinical Trial Update: Assessing Antibiotic Induced Liver Injury for Stratification of Tuberculosis Patients
Completed clinical trial evaluating antibiotic-induced liver injury as a stratification tool for patients with tuberculosis.
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CLINICAL_TRIALS trial_result · 2023-08-31Clinical Trial Update: A Randomized,Double-blind, Placebo Controlled, Multicenter Study to Evaluate the Safety and Efficacy of MT2004 Capsule in DILI Subjects [Phase 2]
A Phase 2 randomized, double-blind, placebo-controlled multicenter study evaluating MT2004 Capsule for safety and efficacy in drug-induced l…
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CLINICAL_TRIALS trial_result · 2023-02-22Clinical Trial Update: Efficacy of N-acetylcysteine to Prevent Anti-tuberculosis Drug-induced Liver Injury: A Randomized Controlled Trial [Phase 2, Phase 3]
A randomized controlled trial evaluating N-acetylcysteine to prevent anti-tuberculosis drug-induced liver injury in tuberculosis patients.
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CLINICAL_TRIALS trial_result · 2023-02-15Clinical Trial Update: 36 Weeks Short-Term Optimization Treatment of Glucocorticosteroid in the Patients With Chronic Recurrent DILI [Phase 1, Phase 2]
Phase 1/2 trial update on short-term optimization of glucocorticosteroid treatment in patients with chronic drug-induced liver injury (DILI)…
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CLINICAL_TRIALS trial_result · 2022-08-04Clinical Trial Update: The Multi-Center, Randomized, Double-blind, Positive Controlled Clinical Trial of Bicyclol in the Treatment of Acute DILI [Phase 3]
A multi-center, randomized Phase 3 trial evaluating bicyclol for acute drug-induced liver injury is in progress with positive-controlled des…