Drug-induced Liver Injury
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: miroliverELAP® for the Treatment of Acute Liver Failure: A Phase 1 Trial [Phase 1]
Phase 1 trial of miroliverELAP for acute liver failure has been completed. The document provides an update on the trial status by Miromatrix…
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: Impact of Silymarin Dosages to Decrease Drug-induced Elevated Liver Enzymes Compared to Placebo [Phase 2, Phase 3]
A completed Phase 2/3 clinical trial evaluating different silymarin dosages versus placebo for lowering elevated liver enzymes in drug-induc…
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CLINICAL_TRIALS trial_result · 2025-11-25Clinical Trial Update: Evaluation of the Efficacy of Fomepizole in the Treatment of Acetaminophen Overdose [Phase 2]
A Phase 2 trial evaluating fomepizole for acetaminophen overdose was terminated; no efficacy results are reported.
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CLINICAL_TRIALS trial_result · 2025-10-09Clinical Trial Update: Digoxin In Treatment of Alcohol Associated Hepatitis [Phase 2]
Phase 2 trial of digoxin in Acute Alcoholic Hepatitis was terminated; no efficacy or safety results are provided in this update.
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CLINICAL_TRIALS trial_result · 2025-08-13Clinical Trial Update: Remaxol® in Patients With Drug-induced Liver Injuries During Cancer Chemotherapy
Remaxol® was studied for drug-induced liver injuries in cancer patients receiving chemotherapy; the clinical trial has completed.
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CLINICAL_TRIALS trial_result · 2025-07-31Clinical Trial Update: Clinical Study to Evaluate Cannabidiol Liver Enzyme Elevations and Drug Interactions [Phase 1]
A Phase 1 FDA-sponsored study evaluating cannabidiol's effects on liver enzymes and potential drug interactions has completed, with results …
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CLINICAL_TRIALS trial_result · 2024-05-21Clinical Trial Update: Assessing Antibiotic Induced Liver Injury for Stratification of Tuberculosis Patients
Completed clinical trial evaluating antibiotic-induced liver injury as a stratification tool for patients with tuberculosis.
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CLINICAL_TRIALS trial_result · 2023-08-31Clinical Trial Update: A Randomized,Double-blind, Placebo Controlled, Multicenter Study to Evaluate the Safety and Efficacy of MT2004 Capsule in DILI Subjects [Phase 2]
A Phase 2 randomized, double-blind, placebo-controlled multicenter study evaluating MT2004 Capsule for safety and efficacy in drug-induced l…
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CLINICAL_TRIALS trial_result · 2023-02-22Clinical Trial Update: Efficacy of N-acetylcysteine to Prevent Anti-tuberculosis Drug-induced Liver Injury: A Randomized Controlled Trial [Phase 2, Phase 3]
A randomized controlled trial evaluating N-acetylcysteine to prevent anti-tuberculosis drug-induced liver injury in tuberculosis patients.
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CLINICAL_TRIALS trial_result · 2023-02-15Clinical Trial Update: 36 Weeks Short-Term Optimization Treatment of Glucocorticosteroid in the Patients With Chronic Recurrent DILI [Phase 1, Phase 2]
Phase 1/2 trial update on short-term optimization of glucocorticosteroid treatment in patients with chronic drug-induced liver injury (DILI)…
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CLINICAL_TRIALS trial_result · 2022-08-04Clinical Trial Update: The Multi-Center, Randomized, Double-blind, Positive Controlled Clinical Trial of Bicyclol in the Treatment of Acute DILI [Phase 3]
A multi-center, randomized Phase 3 trial evaluating bicyclol for acute drug-induced liver injury is in progress with positive-controlled des…
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CLINICAL_TRIALS trial_result · 2022-04-29Clinical Trial Update: Glucocorticosteroid Therapy on Drug-induced Liver Injury: a Prospective Non-randomized Concurrent Control Trial [Phase 4]
A Phase 4 prospective non-randomized concurrent control trial evaluating glucocorticosteroid therapy for drug-induced liver injury.
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CLINICAL_TRIALS trial_result · 2020-11-24Clinical Trial Update: Efficacy and Safety of Polyene Phosphatidylcholine in Treatment of Patients With Acute Drug-induced Liver Injury [Phase 4]
Phase 4 trial update assessing efficacy and safety of polyene phosphatidylcholine for acute drug-induced liver injury.
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CLINICAL_TRIALS trial_result · 2020-08-11Clinical Trial Update: Efficacy and Safety of Glucocorticosteroid Treatment in the Patients With Chronic Recurrent DILI [Phase 1, Phase 2]
Clinical trial investigating the efficacy and safety of glucocorticosteroid treatment in patients with chronic recurrent drug-induced liver …
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CLINICAL_TRIALS trial_result · 2019-02-19Clinical Trial Update: A Trial Of Intravenous N-Acetylcysteine In The Management Of Antituberculous Drug-Induced Hepatitis [Phase 2, Phase 3]
A completed Phase 2/Phase 3 trial evaluated intravenous N-acetylcysteine for management of antituberculous drug-induced hepatitis (drug-indu…
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Sonoelastography: Ultrasound Method to Measure Liver Fibrosis [NA]
A completed clinical trial evaluated sonoelastography, an ultrasound method to measure liver fibrosis; results were posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-04-18Clinical Trial Update: Identifying Changes in Blood (Potential Biomarkers) in Individuals With Drug-Induced Liver Injury
This completed clinical trial investigates potential blood biomarkers in individuals with drug-induced liver injury.
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CLINICAL_TRIALS trial_result · 2017-03-30Clinical Trial Update: Serum miR-122 as a Real-time Detection Biomarker of Drug-induced Liver Injury by Chemotherapy
This clinical trial update investigates serum miR-122 as a real-time biomarker for detecting drug-induced liver injury in patients undergoin…
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CLINICAL_TRIALS trial_result · 2017-02-01Clinical Trial Update: Ultrasound Method to Measure Fibrosis of the Liver in Children [NA]
Update on a pediatric ultrasound method to measure liver fibrosis; the trial was terminated and results were posted in 2017.
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CLINICAL_TRIALS trial_result · 2016-10-26Clinical Trial Update: A Retrospective Study on Drug Induced Liver Injury in China
This document reports the completion of a retrospective clinical trial evaluating drug-induced liver injury in China.
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CLINICAL_TRIALS trial_result · 2016-09-27Clinical Trial Update: Efficacy and Safety Study of Magnesium Isoglycyrrhizinate Injection in Subjects With Acute Drug-induced Liver Injury [Phase 2]
Phase 2 efficacy and safety study of magnesium isoglycyrrhizinate injection for acute drug-induced liver injury has completed.
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CLINICAL_TRIALS trial_result · 2016-09-13Clinical Trial Update: The Protective Effect for Liver Organ in Patients With Anti-TB Drugs Using of Acetylcysteine (NAC) [Phase 4]
A Phase 4 clinical trial evaluating whether N-acetylcysteine protects the liver in patients receiving anti-tuberculosis drugs to prevent dru…
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CLINICAL_TRIALS trial_result · 2013-01-31Clinical Trial Update: Preliminary Evaluation of a Point-Of-Care Liver Function Test [NA]
This completed clinical trial evaluates a point-of-care liver function test for detecting drug-induced liver injury in individuals with HIV …
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CLINICAL_TRIALS trial_result · 2012-07-12Clinical Trial Update: Acetaminophen Adduct Formation in Non-Drinkers Taking Therapeutic Doses of Acetaminophen for Ten Consecutive Days [Phase 4]
A Phase 4 trial update investigates acetaminophen adduct formation in non-drinkers taking therapeutic doses for ten days. The update address…
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CLINICAL_TRIALS trial_result · 2012-02-16Clinical Trial Update: Study of Safety and Efficacy of Different Regimes of Reintroduction of Anti-TB Drugs in Anti-TB Drugs Induced Liver Damage [Phase 4]
This Phase 4 study evaluates safety and efficacy of different regimens for reintroducing anti-tuberculosis drugs in patients who developed l…