Drug-induced Liver Injury
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-04-29Clinical Trial Update: Glucocorticosteroid Therapy on Drug-induced Liver Injury: a Prospective Non-randomized Concurrent Control Trial [Phase 4]
A Phase 4 prospective non-randomized concurrent control trial evaluating glucocorticosteroid therapy for drug-induced liver injury.
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CLINICAL_TRIALS trial_result · 2020-11-24Clinical Trial Update: Efficacy and Safety of Polyene Phosphatidylcholine in Treatment of Patients With Acute Drug-induced Liver Injury [Phase 4]
Phase 4 trial update assessing efficacy and safety of polyene phosphatidylcholine for acute drug-induced liver injury.
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CLINICAL_TRIALS trial_result · 2020-08-11Clinical Trial Update: Efficacy and Safety of Glucocorticosteroid Treatment in the Patients With Chronic Recurrent DILI [Phase 1, Phase 2]
Clinical trial investigating the efficacy and safety of glucocorticosteroid treatment in patients with chronic recurrent drug-induced liver …
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CLINICAL_TRIALS trial_result · 2019-02-19Clinical Trial Update: A Trial Of Intravenous N-Acetylcysteine In The Management Of Antituberculous Drug-Induced Hepatitis [Phase 2, Phase 3]
A completed Phase 2/Phase 3 trial evaluated intravenous N-acetylcysteine for management of antituberculous drug-induced hepatitis (drug-indu…
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Sonoelastography: Ultrasound Method to Measure Liver Fibrosis [NA]
A completed clinical trial evaluated sonoelastography, an ultrasound method to measure liver fibrosis; results were posted in 2017.
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CLINICAL_TRIALS research · 2017-05-30Clinical Trial Update: Comparative Study of Circulating microRNA Changes in Patients With Liver Injury and Healthy Subjects
A clinical study comparing circulating microRNA changes between patients with liver injury (including drug-induced liver injury and liver fa…
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CLINICAL_TRIALS trial_result · 2017-04-18Clinical Trial Update: Identifying Changes in Blood (Potential Biomarkers) in Individuals With Drug-Induced Liver Injury
This completed clinical trial investigates potential blood biomarkers in individuals with drug-induced liver injury.
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CLINICAL_TRIALS safety_alert · 2017-04-14Clinical Trial Update: Surveillance for Early Liver Injuries Caused by Yangxue Shengfa Capsule.
The update describes ongoing surveillance for potential early liver injuries linked to Yangxue Shengfa Capsule, highlighting hepatotoxicity …
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CLINICAL_TRIALS trial_result · 2017-03-30Clinical Trial Update: Serum miR-122 as a Real-time Detection Biomarker of Drug-induced Liver Injury by Chemotherapy
This clinical trial update investigates serum miR-122 as a real-time biomarker for detecting drug-induced liver injury in patients undergoin…
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CLINICAL_TRIALS research · 2017-03-28Clinical Trial Update: Surveillance for Early Liver Injuries Caused by Zhuanggu Guanjie Pill
This clinical trial update documents ongoing safety surveillance for early liver injuries potentially caused by Zhuanggu Guanjie Pill. The d…
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CLINICAL_TRIALS safety_alert · 2017-03-27Clinical Trial Update: Surveillance for Early Liver Injuries Caused by Xianlin Gubao Pill.
Clinical trial update describing surveillance for early liver injuries associated with Xianlin Gubao Pill.
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CLINICAL_TRIALS safety_alert · 2017-03-27Clinical Trial Update: Surveillance for Early Liver Injuries Caused by Xianlin Gubao Granule
Ongoing safety surveillance is being conducted to monitor potential early liver injuries associated with Xianlin Gubao Granule.
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CLINICAL_TRIALS safety_alert · 2017-03-27Clinical Trial Update: Surveillance for Early Liver Injuries Caused by Xianlin Gubao Capsule.
Safety surveillance is underway to monitor potential early liver injuries associated with Xianlin Gubao Capsule. The update highlights conce…
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CLINICAL_TRIALS research · 2017-03-27Clinical Trial Update: Surveillance for Early Liver Injuries Caused by Runzao Zhiyang Capsule.
A clinical trial update describing surveillance for early liver injuries potentially caused by Runzao Zhiyang Capsule.
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CLINICAL_TRIALS research · 2017-03-03Clinical Trial Update: Clarify of Predictive Risk Factors of Chemotherapy-induced Liver Injury [Phase 4]
Phase 4 clinical trial update aiming to identify predictive risk factors for chemotherapy-induced drug-induced liver injury.
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CLINICAL_TRIALS trial_result · 2017-02-01Clinical Trial Update: Ultrasound Method to Measure Fibrosis of the Liver in Children [NA]
Update on a pediatric ultrasound method to measure liver fibrosis; the trial was terminated and results were posted in 2017.
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CLINICAL_TRIALS trial_result · 2016-10-26Clinical Trial Update: A Retrospective Study on Drug Induced Liver Injury in China
This document reports the completion of a retrospective clinical trial evaluating drug-induced liver injury in China.
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CLINICAL_TRIALS trial_result · 2016-09-27Clinical Trial Update: Efficacy and Safety Study of Magnesium Isoglycyrrhizinate Injection in Subjects With Acute Drug-induced Liver Injury [Phase 2]
Phase 2 efficacy and safety study of magnesium isoglycyrrhizinate injection for acute drug-induced liver injury has completed.
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CLINICAL_TRIALS trial_result · 2016-09-13Clinical Trial Update: The Protective Effect for Liver Organ in Patients With Anti-TB Drugs Using of Acetylcysteine (NAC) [Phase 4]
A Phase 4 clinical trial evaluating whether N-acetylcysteine protects the liver in patients receiving anti-tuberculosis drugs to prevent dru…
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CLINICAL_TRIALS withdrawal · 2015-03-05Clinical Trial Update: Acetaminophen in Combination With N-Acetylcysteine (NAC) Versus Placebo in Treating Fever [NA]
A clinical trial evaluating acetaminophen in combination with N-acetylcysteine (NAC) versus placebo for treating fever, in the context of ac…
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CLINICAL_TRIALS safety_alert · 2014-07-08Clinical Trial Update: Risk of Acute Liver Injury in Users of Antimicrobials
This clinical trial update highlights a potential risk of acute liver injury in users of antimicrobials, indicating a safety signal for drug…
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CLINICAL_TRIALS research · 2014-03-17Clinical Trial Update: NAT2 Genotyping in Re-challenge Protocol of INH Titration in Patients With Anti-TB Medications-induced Hepatitis [NA]
Clinical trial update examining NAT2 genotyping to guide a re-challenge protocol and isoniazid titration in patients who developed hepatitis…
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CLINICAL_TRIALS research · 2014-02-19Clinical Trial Update: Establishment of Drug-induced Liver Injury Databases and Application of Circulating microRNA(miRNA)
This clinical trial update describes the establishment of drug-induced liver injury (DILI) databases and the investigation of circulating mi…
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CLINICAL_TRIALS trial_result · 2013-01-31Clinical Trial Update: Preliminary Evaluation of a Point-Of-Care Liver Function Test [NA]
This completed clinical trial evaluates a point-of-care liver function test for detecting drug-induced liver injury in individuals with HIV …
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CLINICAL_TRIALS trial_result · 2012-07-12Clinical Trial Update: Acetaminophen Adduct Formation in Non-Drinkers Taking Therapeutic Doses of Acetaminophen for Ten Consecutive Days [Phase 4]
A Phase 4 trial update investigates acetaminophen adduct formation in non-drinkers taking therapeutic doses for ten days. The update address…