Down Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-07-06Clinical Trial Update: A Study of RO5186582 in Down Syndrome Among Children 6 to 11 Years of Age [Phase 2]
A Phase 2 study evaluating RO5186582 for Down syndrome in children aged 6 to 11 was terminated. No results are provided in the available sni…
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CLINICAL_TRIALS research · 2017-05-30Clinical Trial Update: Examining Social, Emotional, and Cognitive Functioning in People With Fragile X and Down Syndromes
This clinical trial update reports on a completed study evaluating social, emotional, and cognitive functioning in individuals with Fragile …
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CLINICAL_TRIALS trial_result · 2017-05-05Clinical Trial Update: Frequency of Metabolic Syndrome in Down Syndrome Patients
This completed clinical trial examined the frequency of metabolic syndrome in individuals with Down syndrome. The sponsor listed is Universi…
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CLINICAL_TRIALS trial_result · 2017-05-02Clinical Trial Update: Down Syndrome Biomarker Initiative (DSBI)
The Down Syndrome Biomarker Initiative (DSBI) trial has completed, documenting biomarker findings in individuals with Down syndrome and Alzh…
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CLINICAL_TRIALS trial_result · 2017-04-27Clinical Trial Update: Effects of Infant Massage on Acceptance, Commitment and Conscience of Influence of Parents With Down Syndrome Babies [NA]
A clinical trial exploring whether infant massage affects acceptance, commitment, and perceived influence among parents of babies with Down …
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CLINICAL_TRIALS research · 2017-04-11Clinical Trial Update: Performance Analysis in Down Syndrome on Mobile Phone [NA]
A completed clinical trial from the University of Sao Paulo evaluating performance analysis in individuals with Down syndrome using a mobile…
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CLINICAL_TRIALS trial_result · 2017-03-21Clinical Trial Update: Effects of Infant Massage on Development of Down Syndrome Babies [NA]
A clinical trial evaluating the effects of infant massage on development in babies with Down syndrome has completed.
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CLINICAL_TRIALS trial_result · 2016-12-07Clinical Trial Update: Assessment of Bone Density and Bone Turnover Markers in Patients With Down Syndrome and Comparison to the Ts65Dn Model [NA]
Completed clinical trial evaluating bone density and bone turnover markers in individuals with Down syndrome and comparing results to the Ts…
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CLINICAL_TRIALS research · 2016-11-23Clinical Trial Update: Intensive Dysarthria Sessions in Adults and Children With Down Syndrome [NA]
A clinical trial update announcing completion of a study on intensive dysarthria therapy sessions in adults and children with Down syndrome.
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CLINICAL_TRIALS research · 2016-07-11Clinical Trial Update: Non-drug Study to Assess the Suitability of Assessment Scales in Japanese Individuals With Down Syndrome Aged 6-30
A completed non-drug study sponsored by Chugai Pharmaceutical to assess the suitability of clinical assessment scales for Japanese individua…
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CLINICAL_TRIALS trial_result · 2016-05-18Clinical Trial Update: Studying DNA in Samples From Younger Patients With Down Syndrome and Acute Myeloid Leukemia Treated on COG-AAML0431 Clinical Trial
A completed analysis within the COG-AAML0431 trial looked at DNA samples from younger patients with Down syndrome and acute myeloid leukemia…
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CLINICAL_TRIALS research · 2016-05-17Clinical Trial Update: Studying Biomarker Expression in Samples From Patients With Down Syndrome and Acute Myeloid Leukemia or Other Transient Myeloproliferative Disorder
A completed clinical trial update examining biomarker expression in samples from patients with Down syndrome and acute myeloid leukemia or o…
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CLINICAL_TRIALS trial_result · 2016-04-20Clinical Trial Update: Clinical Evaluation of the SEQureDx T21 Test In High Risk Pregnancies
The document reports a completed clinical evaluation of the SEQureDx T21 test for detecting Down syndrome and fetal aneuploidy in high-risk …
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CLINICAL_TRIALS trial_result · 2016-04-20Clinical Trial Update: Clinical Evaluation of the SEQureDx Trisomy Test in Low Risk Pregnancies
The clinical trial evaluating the SEQureDx Trisomy Test for detecting Down syndrome in low-risk pregnancies has completed.
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CLINICAL_TRIALS trial_result · 2016-03-25Clinical Trial Update: Motor Learning Through Virtual Reality Task in Individuals With Down Syndrome [NA]
A completed clinical trial from the University of Sao Paulo studied motor learning using a virtual reality task in individuals with Down syn…
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CLINICAL_TRIALS trial_result · 2016-02-23Clinical Trial Update: Biomarkers in Samples From Patients With Down Syndrome and Acute Megakaryoblastic Leukemia
Clinical trial update summarizing biomarker analyses from samples of patients with Down syndrome-associated acute megakaryoblastic leukemia …
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CLINICAL_TRIALS trial_result · 2016-02-11Clinical Trial Update: Normalization of dyrk1A and APP Function as an Approach to Improve Cognitive Performance and Decelerate AD Progression in DS Subjects: Epigallocatechin Gallate as Therapeutic Tool [Phase 2]
Phase 2 clinical trial update evaluating epigallocatechin gallate (EGCG) to normalize dyrk1A and APP function in individuals with Down syndr…
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CLINICAL_TRIALS trial_result · 2016-02-08Clinical Trial Update: Obstructive Sleep Apnea and Neurocognitive and Cardiovascular Function in Children With Down Syndrome [NA]
A completed clinical trial investigated obstructive sleep apnea and its effects on neurocognitive and cardiovascular function in children wi…
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CLINICAL_TRIALS trial_result · 2016-01-29Clinical Trial Update: A 4-Week Safety Study of Oral ELND005 in Young Adults With Down Syndrome Without Dementia [Phase 2]
Phase 2 safety study of oral ELND005 in young adults with Down syndrome without dementia completed.
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CLINICAL_TRIALS trial_result · 2016-01-20Clinical Trial Update: Can Increased Body Mass Index Prevent Adequate Ultrasound Examination for Trisomy 21 Risk Assessment?
The completed study from Benha University evaluated whether higher body mass index affects the adequacy of ultrasound examinations used in t…
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CLINICAL_TRIALS trial_result · 2015-09-17Clinical Trial Update: Clinical Performance of the MaterniT21 PLUS LDT in Multiple Gestation Pregnancies
Clinical trial update reporting the clinical performance of the MaterniT21 PLUS LDT in multiple gestation pregnancies.
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CLINICAL_TRIALS trial_result · 2015-09-02Clinical Trial Update: A Molecular and Functional Brain Imaging Study in Individuals With Down Syndrome and Healthy Controls Following Single Dose RG1662 [Phase 1]
A Phase 1 brain imaging study evaluating a single dose of RG1662 in individuals with Down syndrome and healthy controls; the study has compl…
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CLINICAL_TRIALS research · 2015-07-28Clinical Trial Update: Detecting Early Onset Pre-eclampsia and Use of Placental Growth Factor (PlGF) for Marker of Trisomy 21
A terminated clinical trial evaluating placental growth factor as a marker for early onset preeclampsia and trisomy 21 detection in pregnanc…
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CLINICAL_TRIALS trial_result · 2015-07-07Clinical Trial Update: Evaluation of a Simplified Method for Diagnosis of Sleep Apnea in Children and Adults With Down Syndrome
A completed clinical trial evaluated a simplified method for diagnosing sleep apnea in individuals with Down syndrome.
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CLINICAL_TRIALS trial_result · 2015-06-03Clinical Trial Update: A New Prenatal Blood Test for Down Syndrome
A completed clinical trial evaluating a new prenatal blood test for detecting Down syndrome (trisomy 21) in fetuses has been reported.