Down Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-03-12Clinical Trial Update: Rivastigmine Study in Adolescents With Down Syndrome [Phase 1, Phase 2]
The document reports the completion of a Phase 1/2 clinical trial of rivastigmine in adolescents with Down syndrome. Results were posted in …
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CLINICAL_TRIALS trial_result · 2015-03-05Clinical Trial Update: Effects of Whole-body Vibration Training on Body Composition in Adolescents With and Without Down Syndrome [NA]
A completed clinical trial examining how whole-body vibration training affects body composition in adolescents with Down syndrome compared t…
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CLINICAL_TRIALS trial_result · 2015-03-03Clinical Trial Update: A Study of RG1662 in Individuals With Down Syndrome [Phase 1]
A Phase 1 study of RG1662 in individuals with Down syndrome has completed.
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CLINICAL_TRIALS research · 2015-03-03Clinical Trial Update: A Non-Drug Study of The Suitability of Neurocognitive Tests And Functioning Scales For The Measurement of Cognitive And Functioning Changes in Individuals With Down Syndrome
This clinical trial update describes a non-drug study evaluating the suitability of neurocognitive tests and functioning scales to measure c…
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CLINICAL_TRIALS trial_result · 2014-11-07Clinical Trial Update: An Interactive Informed Consent and Education Program for Pregnant Women [Phase 1]
Phase 1 completed trial of an interactive informed consent and education program for pregnant women. The study included considerations relat…
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CLINICAL_TRIALS trial_result · 2014-10-16Clinical Trial Update: Use of eHealth in Communication With Patients About Prenatal Diagnosis [NA]
Final results from a completed clinical trial evaluating how eHealth tools can be used to communicate with patients about prenatal diagnosis…
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CLINICAL_TRIALS trial_result · 2014-07-14Clinical Trial Update: Non-invasive Chromosomal Examination of Trisomy Study
The trial update notes the completion of Roche Sequencing Solutions' Non-invasive Chromosomal Examination of Trisomy Study, which investigat…
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CLINICAL_TRIALS research · 2014-03-07Clinical Trial Update: Fluor Varnish With Silver Nanoparticles for Dental Remineralization in Patients With Trisomy 21 [Phase 2]
Phase 2 clinical trial update evaluating Fluor Varnish With Silver Nanoparticles for dental remineralization in individuals with Down syndro…
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CLINICAL_TRIALS trial_result · 2014-01-28Clinical Trial Update: Phase II Study of Florbetaben (BAY94-9172) PET Imaging for Detection/Exclusion of Cerebral β-amyloid. [Phase 2]
Phase II trial evaluating Florbetaben PET imaging (BAY94-9172) for detection/exclusion of cerebral beta-amyloid; study completed with result…
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CLINICAL_TRIALS trial_result · 2014-01-28Clinical Trial Update: A Bicycle Training Intervention [NA]
This update notes the completion of a bicycle training intervention clinical trial conducted by the University of Michigan in individuals wi…
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CLINICAL_TRIALS trial_result · 2014-01-24Clinical Trial Update: Treadmill Training and Orthotic Use in Infants With Down Syndrome [NA]
This clinical trial update reports that the study evaluating treadmill training and orthotic use in infants with Down syndrome is completed …
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CLINICAL_TRIALS trial_result · 2013-12-30Clinical Trial Update: Gait in Children With Down Syndrome While Wearing Orthoses [NA]
A completed clinical trial studied gait in children with Down syndrome while wearing orthoses, with results posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-07-16Clinical Trial Update: Comparison of Aneuploidy Risk Evaluations
This clinical trial update reports on a completed study comparing methods for evaluating fetal aneuploidy risk in pregnancy, including Down …
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CLINICAL_TRIALS trial_result · 2013-07-02Clinical Trial Update: Non-invasive Prenatal Diagnostic Validation Study
The study completed validation of a non-invasive prenatal diagnostic test for fetal chromosomal abnormalities.
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CLINICAL_TRIALS research · 2013-04-23Clinical Trial Update: Down Syndrome Screening Based on Dried Blood Spots and Cell-free Fetal DNA
This clinical trial update discusses screening for Down syndrome (Trisomy 21) using dried blood spots and cell-free fetal DNA. The sponsor i…
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CLINICAL_TRIALS trial_result · 2013-03-13Clinical Trial Update: Egcg, a dyrk1a Inhibitor as Therapeutic Tool for Reversing Cognitive Deficits in Down Syndrome Individuals. [Phase 2]
A Phase 2 clinical trial evaluating EGCG, a DYRK1A inhibitor, as a potential therapy to reverse cognitive deficits in individuals with Down …
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CLINICAL_TRIALS trial_result · 2013-02-13Clinical Trial Update: Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 6 To 10 [Phase 3]
Phase 3 trial evaluating donepezil for cognitive dysfunction in children with Down syndrome was terminated; results posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-02-01Clinical Trial Update: Efficacy and Safety of Memantine Hydrochloride in Enhancing the Cognitive Abilities of Young Adults With Down Syndrome [Phase 4]
Phase 4 trial evaluating memantine hydrochloride for cognitive enhancement in young adults with Down syndrome; results were posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-01-10Clinical Trial Update: Prenatal Test for Fetal Aneuploidy Detection
Completed clinical trial update on Roche's prenatal test for fetal aneuploidy detection, including Down syndrome (Trisomy 21).
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CLINICAL_TRIALS trial_result · 2013-01-01Clinical Trial Update: Eyelash Line Resection for Entropion Associated With Down's Syndrome [NA]
A completed clinical trial assessing eyelash line resection to correct entropion in individuals with Down syndrome.
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CLINICAL_TRIALS trial_result · 2012-11-28Clinical Trial Update: Efficacy of Rivastigmine in Patients With Down Syndrome [NA]
A completed clinical trial assessed the efficacy of rivastigmine in patients with Down syndrome.
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CLINICAL_TRIALS trial_result · 2012-05-09Clinical Trial Update: Multicenter Vitamin E Trial in Aging Persons With Down Syndrome [Phase 3]
The document reports completion of the multicenter Phase 3 trial of vitamin E in aging individuals with Down syndrome and Alzheimer’s diseas…
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CLINICAL_TRIALS research · 2012-05-04Clinical Trial Update: Vitamin E in Aging Persons With Down Syndrome [Phase 3]
A Phase 3 clinical trial evaluating vitamin E in aging individuals with Down syndrome and Alzheimer's disease; the current status is unknown…
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CLINICAL_TRIALS trial_result · 2012-03-22Clinical Trial Update: Correlations Phenotype / Genotype in Down Syndrome
This completed clinical trial, sponsored by Institut Jerome Lejeune, investigates correlations between phenotype and genotype in individuals…
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CLINICAL_TRIALS trial_result · 2012-03-22Clinical Trial Update: Pilot Study of Auto-immune Abnormalities Associated With Down Syndrome
This clinical trial update notes the completion of a pilot study investigating autoimmune abnormalities in people with Down syndrome.