Down Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Results: Developing a Down Syndrome Health Instrument
Completed clinical trial evaluating a health instrument for individuals with Down syndrome; results posted.
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia [Phase 3]
Phase 3 trial evaluating blinatumomab in combination with chemotherapy for newly diagnosed B lymphoblastic leukemia; the study is currently …
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Guanfacine for Hyperactivity in Children With Down Syndrome (HYPEbeGONE_DS) [Phase 2]
A Phase 2 trial evaluating guanfacine for hyperactivity and impulsivity in children with Down syndrome has been terminated.
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Effects of a Structured Physical Activity Program on Balance and Functional Performance in Children With Down Syndrome [NA]
A completed clinical trial assesses the impact of a structured physical activity program on balance and functional performance in children w…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Investigating the Impact of JASPER Behavioral Therapy in Children With Down Syndrome [NA]
The clinical trial evaluating JASPER Behavioral Therapy in children with Down syndrome has completed. Sponsor: Boston Children's Hospital.
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: Non Invasive Prenatal Diagnosis of Trisomy 21 by Genetic Analysis of Circulating Fetal Cells [NA]
A clinical trial evaluating non-invasive prenatal diagnosis of Down syndrome by analyzing circulating fetal cells has completed.
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: Decreasing Alzheimer's Risk Through oNline Choreographed Exercise - Down Syndrome [NA]
A completed trial evaluated whether an online choreographed exercise program reduces Alzheimer's risk in people with Down syndrome. Results …
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: Dilated Versus Non-Dilated Wavefront Corrections for Patients With Down Syndrome [Phase 2]
A Phase 2 trial evaluating dilated versus non-dilated wavefront corrections for correcting refractive errors in patients with Down syndrome …
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: Hero: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK) and Pharmacodynamics (PD) of ION269 in Participants With Down Syndrome (DS) at Risk for Alzheimer's Disease (AD) [Phase 1]
A Phase 1 trial evaluating the safety, tolerability, pharmacokinetics, and pharmacodynamics of ION269 in participants with Down syndrome at …
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CLINICAL_TRIALS trial_result · 2026-02-04Clinical Trial Update: Blood Flow Regulation in Individuals With Down Syndrome - Training Study [NA]
A completed clinical trial evaluating blood flow regulation in individuals with Down syndrome; results have been posted.
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CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: Turkish Adaptation of Segmental Assessment of Trunk Control Scale
This document reports the completion of a clinical trial evaluating the Turkish adaptation of the Segmental Assessment of Trunk Control Scal…
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CLINICAL_TRIALS trial_result · 2026-01-15Clinical Trial Update: Trisomy of Chromosome 21 Diagnosis by High Output Sequencing
This trial update announces the completion of a study evaluating high-output sequencing for diagnosing Trisomy 21, including translocation v…
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Caregiver-Involved Nutrition Education in Down Syndrome [NA]
A completed clinical trial evaluating caregiver-involved nutrition education for individuals with Down syndrome.
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: 19/5000 (SYNAPSOT21) Predictive Factors of Sleep Apnea Syndrome in Down Syndrome
This completed clinical trial (NCT03445962) studied predictive factors for obstructive sleep apnea in individuals with Down syndrome. The re…
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: Resilience Training Intervention: Its Effect on Parental Acceptance/Rejection and Burden of Children With Down Syndrome [NA]
This clinical trial update describes Ain Shams University’s resilience training intervention aimed at affecting parental acceptance/rejectio…
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CLINICAL_TRIALS trial_result · 2025-12-11Clinical Trial Update: Tofacitinib for Immune Skin Conditions in Down Syndrome [Phase 2]
A Phase 2 trial evaluating tofacitinib for immune-mediated skin conditions in individuals with Down syndrome has completed, with results pos…
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CLINICAL_TRIALS trial_result · 2025-12-09Clinical Trial Update: Paternal Age and Fetal Aneuploidy
A completed clinical trial investigating the relationship between paternal age and fetal aneuploidy. The condition studied includes trisomy …
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CLINICAL_TRIALS trial_result · 2025-10-14Clinical Trial Update: Assessing Malleability of Spatial Abilities in Down Syndrome [NA]
A completed clinical trial evaluated whether spatial abilities can be modified in individuals with Down syndrome; results were posted on 202…
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CLINICAL_TRIALS trial_result · 2025-09-19Clinical Trial Update: Non Invasive Prenatal Testing of Down Syndrome [NA]
The clinical trial evaluating non-invasive prenatal testing for Down syndrome has completed.
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: Neuro-Nutrition to Support Physiological Function and Cognitive Skills in People With Down Syndrome, Autism Spectrum Disorder, and ADHD [NA]
Clinical trial update shows the Neuro-Nutrition intervention study for Down syndrome, Autism Spectrum Disorder, and Attention Deficit Hypera…
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Effects of Orofacial Therapy and Therapeutic Yoga in Children With Down Syndrome [NA]
A clinical trial investigating orofacial therapy and therapeutic yoga in children with Down syndrome has completed.
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Awareness of Families With Down Syndrome Children About the Role of Physical Therapy in Egypt
A Cairo University–led clinical trial in Egypt completed an awareness program for families of children with Down syndrome on the role of phy…
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CLINICAL_TRIALS trial_result · 2025-08-19Clinical Trial Update: Medications for Obstructive Sleep Apnea In Children With Down Syndrome [Phase 2]
Phase 2 clinical trial update evaluating medications for obstructive sleep apnea in children with Down syndrome; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-08-03Clinical Trial Update: Predictors of Speech Ability in Down Syndrome [NA]
Completed clinical trial investigating predictors of speech ability in individuals with Down syndrome; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: Impact of an Orthotic Garment on Gross Motor Skills for Infants With Down Syndrome [NA]
Completed clinical trial evaluating the impact of an orthotic garment on gross motor skills in infants with Down syndrome.