Down Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-04-19Clinical Trial Update: Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (HCl) (Aricept) In Treating Cognitive Dysfunction Exhibited By Children With Down Syndrome [Phase 2]
Phase 2 trial evaluating donepezil hydrochloride for cognitive dysfunction in children with Down syndrome has completed; results posted.
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CLINICAL_TRIALS trial_result · 2021-03-29Clinical Trial Update: Evaluating The Safety Of Donepezil Hydrochloride (Aricept) For Up To 1 Year In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome - Follow-Up To A 10-Week, Double-Blind, Placebo-Controlled Trial [Phase 2]
A Phase 2 trial update evaluating safety of donepezil hydrochloride in children with Down syndrome over up to one year; the study was termin…
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CLINICAL_TRIALS trial_result · 2021-02-11Clinical Trial Update: the Effect of Cerebrolysin on Physical and Mental Functions of Down Syndrome [Phase 2]
Phase 2 clinical trial evaluating the effects of Cerebrolysin on physical and mental functions in individuals with Down syndrome has complet…
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CLINICAL_TRIALS research · 2020-06-09Clinical Trial Update: The Effects of Inhalational Anaesthetics in Cognitive Functions in Down Syndrome Patients [Phase 2]
Phase 2 clinical trial evaluating the effects of inhalational anaesthetics on cognitive functions in individuals with Down syndrome, complet…
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CLINICAL_TRIALS research · 2020-05-13Clinical Trial Update: Efficacy Assessment of Systematic Treatment With Folinic Acid and Thyroid Hormone on Psychomotor Development of Down Syndrome Young Children [Phase 3]
A Phase 3 trial assessing folinic acid and thyroid hormone treatment for psychomotor development in young children with Down syndrome has co…
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CLINICAL_TRIALS trial_result · 2020-04-21Clinical Trial Update: Balance Bike Training in Down Syndrome [NA]
Completed clinical trial evaluating balance bike training for improving postural balance in individuals with Down syndrome; results posted i…
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CLINICAL_TRIALS trial_result · 2019-12-06Clinical Trial Update: Investigation of the Safety of Intranasal Glulisine in Down Syndrome [Phase 1]
Phase 1 trial investigating the safety of intranasal glulisine in individuals with Down syndrome has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-06-13Clinical Trial Update: Treatment Trial of Subclinical Hypothyroidism in Down Syndrome [NA]
A completed clinical trial evaluating treatment for subclinical hypothyroidism in individuals with Down syndrome; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Gait Parameters of Persons With Down Syndrome With and Without Orthotics Using GaitRite
A completed clinical trial examined gait parameters in individuals with Down syndrome with and without orthotics using the GaitRite system.
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CLINICAL_TRIALS trial_result · 2019-01-09Clinical Trial Update: Down Syndrome Metabolic Health Study
Clinical trial update for a Down Syndrome metabolic health study (NCT01821300) completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2018-07-30Clinical Trial Update: Obstructive Sleep Apnea and Down Syndrome: Clinical Examination Issue [NA]
A completed clinical trial update related to obstructive sleep apnea in individuals with Down syndrome, noting a clinical examination issue.
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CLINICAL_TRIALS trial_result · 2018-07-12Clinical Trial Update: Phenotypic Specific Communication Intervention for Children With Down Syndrome [NA]
The Vanderbilt University-sponsored study evaluating a phenotypic-specific communication intervention for children with Down syndrome has co…
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CLINICAL_TRIALS research · 2018-07-05Clinical Trial Update: Correlation Between Optic Nerve Vessel Anomalies, Serum Angiogenic Factors and Renal Anomalies in Down Syndrome Children [NA]
This clinical trial explores potential correlations between optic nerve vessel anomalies, serum angiogenic factors, and renal anomalies in c…
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CLINICAL_TRIALS trial_result · 2018-06-12Clinical Trial Update: Indicators of Growth, Nutritional Status and Comorbide Disorders of Newborns With Down Syndrome
A completed clinical trial assessing indicators of growth, nutritional status, and comorbidities in newborns with Down syndrome.
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CLINICAL_TRIALS research · 2018-06-07Clinical Trial Update: Assessment of Women's Insight and Understanding of Down's Syndrome Screening by Non-invasive Prenatal Testing (NIPT) During Their First Ultrasound
A clinical trial update describing a study that assesses women's insight and understanding of Down syndrome screening using non-invasive pre…
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CLINICAL_TRIALS trial_result · 2018-06-04Clinical Trial Update: Treatment of Sleep Disturbances in School-age Children With Down Syndrome [NA]
A clinical trial investigating treatments for sleep disturbances in school-age children with Down syndrome has completed, sponsored by Cinci…
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CLINICAL_TRIALS research · 2018-04-27Clinical Trial Update: Turkish Version of The Measure of Processes of Care (MPOC)
A clinical trial update notes the Turkish version of the Measure of Processes of Care (MPOC) being pursued by Hacettepe University, with lis…
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CLINICAL_TRIALS trial_result · 2018-04-23Clinical Trial Update: Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 11 To 17 [Phase 3]
Phase 3 trial evaluating donepezil hydrochloride (Aricept) for cognitive dysfunction in children with Down syndrome aged 11 to 17 was termin…
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CLINICAL_TRIALS research · 2017-11-24Clinical Trial Update: Interrater Reliability of Infant Motor Profile
This clinical trial update reports on the interrater reliability of the Infant Motor Profile scoring in infants at risk for motor disorders.
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CLINICAL_TRIALS trial_result · 2017-10-25Clinical Trial Update: A Study of RG1662 in Adults and Adolescents With Down Syndrome (CLEMATIS) [Phase 2]
A Phase 2 trial of RG1662 in adults and adolescents with Down syndrome (CLEMATIS) has completed.
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CLINICAL_TRIALS research · 2017-10-25Clinical Trial Update: Non-drug Study to Evaluate the Suitability of Neurocognitive Tests and Functioning Scales for the Measurement of Cognitive and Functioning Changes in Children With Down Syndrome
This is a completed non-drug clinical trial evaluating neurocognitive tests and functioning scales for measuring cognitive and functional ch…
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CLINICAL_TRIALS trial_result · 2017-10-18Clinical Trial Update: Parent Supported Weight Reduction in Down Syndrome [NA]
A completed clinical trial update examining parent-supported weight reduction for individuals with Down syndrome.
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: A Double-blind, Placebo-controlled Comparative Study and Open-label Extension Study to Confirm the Efficacy and Safety of E2020 in Subjects With Down Syndrome Having Regression Symptoms and Disabled Activities of Daily Living. [Phase 2]
A Phase 2 double-blind, placebo-controlled study with an open-label extension assessing the efficacy and safety of E2020 (donepezil) in indi…
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CLINICAL_TRIALS trial_result · 2017-08-15Clinical Trial Update: T21,18 and 13 Screening by Cell Free Fetal DNA in Low Risk Patients [NA]
A completed clinical trial evaluated cell-free fetal DNA screening for Trisomy 21, 18, and 13 in low-risk pregnancies.
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CLINICAL_TRIALS research · 2017-07-19Clinical Trial Update: A Screening Protocol to Assess Adults and Adolescents With Down Syndrome for Eligibility For Upcoming Study of RG1662 (Study BP27832)
The document describes a screening protocol to determine eligibility of adults and adolescents with Down syndrome for an upcoming Roche stud…