Down Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: LEvetiracetam to Prevent Seizures in Symptomatic Alzheimer's Disease in Adults With Down Syndrome [Phase 3]
A Phase 3 clinical trial is evaluating whether Levetiracetam can prevent seizures in adults with Down syndrome who have symptomatic Alzheime…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Optimizing the Management of OSA in Children With Down Syndrome
This clinical trial, sponsored by University Hospital Strasbourg, aims to optimize the management of obstructive sleep apnea in children wit…
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Caregiver-Involved Nutrition Education in Down Syndrome [NA]
A completed clinical trial evaluating caregiver-involved nutrition education for individuals with Down syndrome.
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: 19/5000 (SYNAPSOT21) Predictive Factors of Sleep Apnea Syndrome in Down Syndrome
This completed clinical trial (NCT03445962) studied predictive factors for obstructive sleep apnea in individuals with Down syndrome. The re…
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: Resilience Training Intervention: Its Effect on Parental Acceptance/Rejection and Burden of Children With Down Syndrome [NA]
This clinical trial update describes Ain Shams University’s resilience training intervention aimed at affecting parental acceptance/rejectio…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: A Multicenter Retrospective Analysis of Postoperative Respiratory Complications in Children With Obstructive Sleepapnea
A multicenter retrospective study examining postoperative respiratory complications in children with obstructive sleep apnea, currently recr…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Phenolic Complex k110-42 Therapy on Cognitive Functions in Down Children [Phase 3]
A Phase 3 clinical trial evaluating Phenolic Complex k110-42 for cognitive function in children with Down syndrome; the study is not yet rec…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study) [Phase 1, Phase 2]
This clinical trial update indicates that AC Immune's Alzheimer’s-focused candidate ACI-24.060 is being evaluated in Phase 1 and Phase 2 stu…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Sensitivity of the NIH Toolbox to Stimulant Treatment in Intellectual Disabilities [Phase 1]
Phase 1 clinical trial update evaluating how sensitive the NIH Toolbox is to stimulant treatment in individuals with intellectual disabiliti…
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: NAD Augmentation to Prevent or Reverse Alzheimer's Disease in People With Down Syndrome [Phase 1]
Phase 1 clinical trial evaluating NAD augmentation to prevent or reverse Alzheimer's disease in people with Down syndrome; currently not yet…
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CLINICAL_TRIALS trial_result · 2025-12-11Clinical Trial Update: Tofacitinib for Immune Skin Conditions in Down Syndrome [Phase 2]
A Phase 2 trial evaluating tofacitinib for immune-mediated skin conditions in individuals with Down syndrome has completed, with results pos…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Role of Early Motor Experience in Infants With Down Syndrome [NA]
This document reports on a completed clinical trial conducted by Georgia State University examining the role of early motor experience in in…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Leucettinib-21 First-in-Human Phase 1 in Healthy Volunteers and Subjects With Down Syndrome and Alzheimer's Disease [Phase 1]
A first-in-human Phase 1 study of Leucettinib-21 is enrolling healthy volunteers and individuals with Down syndrome and Alzheimer's disease.…
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CLINICAL_TRIALS trial_result · 2025-12-09Clinical Trial Update: Paternal Age and Fetal Aneuploidy
A completed clinical trial investigating the relationship between paternal age and fetal aneuploidy. The condition studied includes trisomy …
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Cervical Spine Abnormalities in Down Syndrome
This clinical trial update from Sohag University examines cervical spine abnormalities in people with Down syndrome. The study is currently …
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Effects of Vojta Therapy on Functional Mobility and Gait Parameters in Children With Down Syndrome [NA]
A clinical trial is investigating the effects of Vojta Therapy on functional mobility and gait in children with Down syndrome and is current…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Physical Fitness in DS: A Comparison of Cuevas Medak and Rebound Exercises [NA]
This clinical trial compares Cuevas Medak and rebound exercises to evaluate physical fitness in individuals with Down syndrome; recruitment …
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Amyloid Lowering for Alzheimer's in Down's With Donanemab Investigation [Phase 4]
A Phase 4 clinical trial to evaluate donanemab for amyloid lowering in Alzheimer's disease associated with Down syndrome is not yet recruiti…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Effects of Powerball in Children With Down Syndrome [NA]
This document reports a recruiting clinical trial evaluating the effects of Powerball in children with Down syndrome.
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Exploring Sympathetic Nervous System Function in Individuals With Down Syndrome [Phase 3]
A Phase 3 clinical trial update from the University of Colorado, Denver investigates sympathetic nervous system function in individuals with…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: The Efficacy of Therapy in Patients With Acute Myeloid Leukemia and Down Syndrome in Russia [Phase 3]
A Phase 3 clinical trial in Russia evaluating the efficacy of a therapy for patients with acute myeloid leukemia and Down syndrome is curren…
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: The Effect of the HEP Approach in Infants With Down Syndrome [NA]
A clinical trial update indicates ongoing recruitment for evaluating the HEP Approach in infants with Down syndrome.
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CLINICAL_TRIALS research · 2025-10-24Clinical Trial Update: The Human Trisome Project
Clinical trial update for The Human Trisome Project (NCT02864108) shows the University of Colorado, Denver is currently recruiting participa…
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CLINICAL_TRIALS trial_result · 2025-10-14Clinical Trial Update: Assessing Malleability of Spatial Abilities in Down Syndrome [NA]
A completed clinical trial evaluated whether spatial abilities can be modified in individuals with Down syndrome; results were posted on 202…
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: Computer Models of Airways in Children and Young Adults With Sleep Apnea and Down Syndrome
This ClinicalTrials.gov study update describes computer modeling of airways in children and young adults with Down syndrome and obstructive …