Down Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: Validation of Sleep Questionnaires in the Down Syndrome Population [NA]
This update describes validation of sleep questionnaires for individuals with Down syndrome to assess obstructive sleep apnea, with the stud…
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CLINICAL_TRIALS trial_result · 2025-09-19Clinical Trial Update: Non Invasive Prenatal Testing of Down Syndrome [NA]
The clinical trial evaluating non-invasive prenatal testing for Down syndrome has completed.
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Effects of Hypoglossal Nerve Stimulation on Cognition and Language in Down Syndrome and Obstructive Sleep Apnea [Phase 3]
Phase 3 clinical trial evaluating hypoglossal nerve stimulation for cognition and language in individuals with Down syndrome and obstructive…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Prevalence of Translocation Phenotyping in Children With Down Syndrome and Their Parents
The trial aims to determine how often translocation phenotyping is performed in children with Down syndrome and in their parents. The study …
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: Neuro-Nutrition to Support Physiological Function and Cognitive Skills in People With Down Syndrome, Autism Spectrum Disorder, and ADHD [NA]
Clinical trial update shows the Neuro-Nutrition intervention study for Down syndrome, Autism Spectrum Disorder, and Attention Deficit Hypera…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Evaluation of Fetal Bladder Emptying During the 11-14 Weeks' Ultrasound Examination as a Negative Predictive Marker for Chromosomal Abnormalities
A study evaluating fetal bladder emptying at 11-14 weeks as a negative predictive marker for chromosomal abnormalities, to inform prenatal s…
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Effects of Orofacial Therapy and Therapeutic Yoga in Children With Down Syndrome [NA]
A clinical trial investigating orofacial therapy and therapeutic yoga in children with Down syndrome has completed.
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Awareness of Families With Down Syndrome Children About the Role of Physical Therapy in Egypt
A Cairo University–led clinical trial in Egypt completed an awareness program for families of children with Down syndrome on the role of phy…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Drumming Lessons' Influence on Children With Down Syndrome [NA]
A Vanderbilt University study is exploring whether drumming lessons influence outcomes in children with Down syndrome; the trial status is n…
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CLINICAL_TRIALS trial_result · 2025-08-19Clinical Trial Update: Medications for Obstructive Sleep Apnea In Children With Down Syndrome [Phase 2]
Phase 2 clinical trial update evaluating medications for obstructive sleep apnea in children with Down syndrome; results have been posted.
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: Parent Child Interaction Therapy vs Conventional Parent Led Therapy in Down Syndrome [NA]
A completed clinical trial comparing Parent-Child Interaction Therapy to conventional parent-led therapy in individuals with Down syndrome a…
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: PAP for Children With DS and OSAS [NA]
A clinical trial update indicates a study evaluating positive airway pressure therapy for children with Down syndrome and obstructive sleep …
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: Using Technologies to Promote HEalthy Lifestyles in Adolescents With Intellectual Disabilities [NA]
A clinical trial update indicates that a University of Seville study aiming to promote healthy lifestyles in adolescents with intellectual d…
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CLINICAL_TRIALS trial_result · 2025-08-03Clinical Trial Update: Predictors of Speech Ability in Down Syndrome [NA]
Completed clinical trial investigating predictors of speech ability in individuals with Down syndrome; results have been posted.
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: tDCS for Catatonic Depression in Down Syndrome: A Pilot Study [NA]
This clinical trial update describes a pilot study using transcranial direct current stimulation to treat catatonic depression in individual…
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: Impact of an Orthotic Garment on Gross Motor Skills for Infants With Down Syndrome [NA]
Completed clinical trial evaluating the impact of an orthotic garment on gross motor skills in infants with Down syndrome.
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CLINICAL_TRIALS trial_result · 2025-07-15Clinical Trial Update: Effects of Play Based Therapy on Attention Level of Children With Down Syndrome [NA]
Riphah International University studied the effects of play-based therapy on attention in children with Down syndrome; the clinical trial ha…
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: Comparative Effects of Dual Task Training and Embodied Learning on Dual Task Performance in Children With Down Syndrome [NA]
A completed clinical trial comparing dual task training versus embodied learning for improving dual-task performance in children with Down s…
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Elucidating Age-related Comorbidity Patterns in Down Syndrome (DS)
A completed clinical trial investigating age-related comorbidity patterns in individuals with Down syndrome.
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: Dual Task Balance Exercises and Vestibular Stimulation for Children With Down Syndrome [NA]
A clinical trial examining dual task balance exercises combined with vestibular stimulation in children with Down syndrome has completed.
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CLINICAL_TRIALS trial_result · 2025-07-04Clinical Trial Update: Non-Invasive Brain Stimulation to Improve Language in Down Syndrome. [NA]
A clinical trial is investigating non-invasive brain stimulation to improve language in individuals with Down syndrome and is currently recr…
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CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Neuropsychological Evaluation in Intellectual Disability (ENDI)
ClinicalTrials.gov entry for the ENDI study, a neuropsychological evaluation project in individuals with Down syndrome, currently not yet re…
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Cholinergic Integrity in Down Syndrome in Association With Aging, Alzheimer's Disease Pathology, and Cognition [Phase 2]
Phase 2 clinical trial update from Vanderbilt University Medical Center examining cholinergic integrity in individuals with Down syndrome to…
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CLINICAL_TRIALS other · 2025-06-19Clinical Trial Update: A VIRTUAL Three-month Intervention Study of the Effects of a Smartphone Application (HippoCamera) on Memory in Teens and Young Adults With Down Syndrome [NA]
A clinical trial is recruiting teens and young adults with Down syndrome to study the effects of the HippoCamera smartphone app on memory.
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome [Phase 3]
Phase 3 trial evaluating response-based chemotherapy in younger patients with Down syndrome who have newly diagnosed acute myeloid leukemia …