Down Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Self-Supporting Nasopharyngeal Airway (ssNPA) Treating Upper Airway Obstruction in Hypotonia [NA]
A University of Michigan clinical trial is recruiting to evaluate a self-supporting nasopharyngeal airway device for treating upper airway o…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Brain Outcomes With Lifestyle Change in Down Syndrome [NA]
A clinical trial is currently recruiting to assess how lifestyle changes affect brain outcomes in people with Down syndrome, with potential …
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: Dilated Versus Non-Dilated Wavefront Corrections for Patients With Down Syndrome [Phase 2]
A Phase 2 trial evaluating dilated versus non-dilated wavefront corrections for correcting refractive errors in patients with Down syndrome …
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Assessment of Diastolic Function During the Transitional Period and Infancy Using Serial Echocardiography
Clinical trial entry for an observational study evaluating diastolic function in newborns during the transitional period and infancy using s…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Therapies for Down Syndrome Regression Disorder [Phase 2]
Phase 2 clinical trial update for therapies addressing Down Syndrome Regression Disorder. The study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: The Neurocognitive Bases of Trust in Intellectual Disability
A clinical trial update describing research into the neurocognitive bases of trust in individuals with intellectual disability, focusing on …
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia
A clinical trial update describing a study to learn more about the health of persons with Down syndrome after treatment for acute leukemia.
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Effects of Jump Rope on Navicular Drop in Down Syndrome [NA]
A recruiting clinical trial is evaluating whether a jump rope exercise program can affect navicular drop in individuals with Down syndrome.
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Effect of Cognitive-motor Training Versus Pilates Exercises on Postural Stability in Down Syndrome. [NA]
Ongoing clinical trial comparing cognitive-motor training to Pilates exercises to assess effects on postural stability in children with Down…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Adapting RDAD for DS [NA]
A clinical trial update indicates the University of Kansas Medical Center is adapting the RDAD program for individuals with Down syndrome an…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Physical Activity and Community EmPOWERment Project [NA]
Clinical trial update from the University of North Carolina on the Physical Activity and Community Empowerment project. The study is current…
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: Hero: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK) and Pharmacodynamics (PD) of ION269 in Participants With Down Syndrome (DS) at Risk for Alzheimer's Disease (AD) [Phase 1]
A Phase 1 trial evaluating the safety, tolerability, pharmacokinetics, and pharmacodynamics of ION269 in participants with Down syndrome at …
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Rebound Therapy on Ventilatory Functions in Down Syndrome [NA]
The trial 'Rebound Therapy on Ventilatory Functions in Down Syndrome' is not yet recruiting and is studying the effects of rebound therapy o…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Proactive Speech and Language Intervention for Infants With Down Syndrome [NA]
This update describes an ongoing clinical trial evaluating proactive speech and language intervention for infants with Down syndrome, sponso…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS) [NA]
This is a clinical trial update for TOPS-DS, describing recruitment for a personalized surgical treatment approach for obstructive sleep apn…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Developing a Down Syndrome Health Instrument
A Massachusetts General Hospital clinical trial has completed development work on a Down syndrome health instrument. The tool is intended to…
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CLINICAL_TRIALS trial_result · 2026-02-04Clinical Trial Update: Blood Flow Regulation in Individuals With Down Syndrome - Training Study [NA]
A completed clinical trial evaluating blood flow regulation in individuals with Down syndrome; results have been posted.
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Effects of (tDCS) Combined With Virtual Reality Versus CPT on Brain, Cognitive, and GMS in Children With DS. [NA]
A clinical trial is evaluating whether transcranial direct current stimulation (tDCS) plus virtual reality improves brain function, cognitio…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: The Impact of Core Stability Versus Respiratory Muscle Strengthening Exercises on Bone Mineral Density in Children With Down Syndrome [NA]
A ClinicalTrials.gov study comparing core stability to respiratory muscle strengthening exercises to evaluate effects on bone mineral densit…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Compassionate Use Study of Epi-ON Corneal Collagen Crosslinking Performed Using UVA Exposure on Eyes With Ectatic Corneal Diseases for Subjects With Down Syndrome [Phase 3]
Phase 3 compassionate-use trial evaluating epithelial-on corneal collagen crosslinking with UVA exposure for eyes with ectatic corneal disea…
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CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: Turkish Adaptation of Segmental Assessment of Trunk Control Scale
This document reports the completion of a clinical trial evaluating the Turkish adaptation of the Segmental Assessment of Trunk Control Scal…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Group-based Resistance Training for Adults With Down Syndrome [NA]
A clinical trial update for a group-based resistance training program in adults with Down syndrome, noting the study is active but not recru…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Immune Profile and Respiratory Parameters in Down Syndrome Children With Acute Pneumonia: Pre-Intervention Analysis
A clinical trial assessing immune profiles and respiratory parameters in Down syndrome children with acute pneumonia before any intervention…
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CLINICAL_TRIALS trial_result · 2026-01-15Clinical Trial Update: Trisomy of Chromosome 21 Diagnosis by High Output Sequencing
This trial update announces the completion of a study evaluating high-output sequencing for diagnosing Trisomy 21, including translocation v…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Effects of Chronic Creatine and Beta-Hydroxy-Beta-Methylbutyrate Supplementation on Oxidative Stress, Inflammation, Muscle Strength, and Body Composition in Individuals With Down Syndrome [NA]
This clinical trial is evaluating the effects of chronic creatine and beta-hydroxy-beta-methylbutyrate supplementation on oxidative stress, …