Diffuse Large B-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-08-26Clinical Trial Update: Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels [Phase 1]
Phase 1 trial assessing the pharmacokinetic interactions of itraconazole and rifampin with tazemetostat; results published for patients with…
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CLINICAL_TRIALS other · 2024-08-26Clinical Trial Update: A Study of Trilaciclib Combined With Chemotherapy in the Treatment of Diffuse Large B-Cell Lymphoma Patients [Phase 2]
A Phase 2 clinical trial is evaluating trilaciclib in combination with chemotherapy for diffuse large B-cell lymphoma and is currently recru…
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CLINICAL_TRIALS research · 2024-08-26Clinical Trial Update: Blood Sample Markers of Reproductive Hormones in Assessing Ovarian Reserve in Younger Patients With Newly Diagnosed Lymphomas
A completed clinical trial evaluated blood markers of reproductive hormones to assess ovarian reserve in younger patients with newly diagnos…
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CLINICAL_TRIALS research · 2024-08-22Clinical Trial Update: Optimizing ctDNA-based MRD Assessment in DLBCL, MCL, and FL Patients Undergoing CAR Therapy
This clinical trial update from Adaptive Biotechnologies aims to optimize ctDNA-based minimal residual disease assessment in patients with f…
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CLINICAL_TRIALS research · 2024-08-22Clinical Trial Update: CAR T-cell Therapy in Combination With Glofitamab for Relapsed/Refractory Large B-Cell Lymphoma With High-Risk Prognostic Factors [Phase 2]
A Phase 2 clinical trial update evaluating the combination of CAR T-cell therapy with glofitamab for relapsed/refractory diffuse large B-cel…
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CLINICAL_TRIALS trial_result · 2024-08-21Clinical Trial Update: CD19-targeted CAR T Cells for Relapsed and Refractory (R/R) Large B-cell Lymphoma [Phase 2]
This document provides an update on a Phase 2 clinical trial of CD19-targeted CAR T cells for relapsed or refractory large B-cell lymphoma.
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CLINICAL_TRIALS research · 2024-08-21Clinical Trial Update: CD19-targeted CAR T Cells for Relapsed or Refractory (R/R) Large B-cell Lymphoma [Phase 2]
Phase 2 clinical trial update investigating CD19-targeted CAR T cells for relapsed or refractory large B-cell lymphoma, currently recruiting…
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CLINICAL_TRIALS trial_result · 2024-08-21Clinical Trial Update: ENABLE-1 (Engaging Toll-like Receptor Signalling for B-cell Lymphoma Chimeric Antigen Receptor Therapy) [Phase 1]
The ENABLE-1 Phase 1 trial investigates Toll-like receptor signaling to enhance B-cell lymphoma CAR-T therapy, with the study currently list…
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CLINICAL_TRIALS trial_result · 2024-08-20Clinical Trial Update: CLBR001 and SWI019 in Patients With Relapsed / Refractory B-cell Malignancies [Phase 1]
Phase 1 trial update for CLBR001 and SWI019 in relapsed/refractory B-cell malignancies has completed enrollment in a study targeting multipl…
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CLINICAL_TRIALS research · 2024-08-15Clinical Trial Update: A Study of Zanubrutinib in Combination With Polatuzumab Vedotin, Bendamustine and Rituximab in the Treatment of Relapsed/Refractory Diffuse Large B-cell Lymphoma [Phase 2]
Phase 2 clinical trial evaluating zanubrutinib in combination with polatuzumab vedotin, bendamustine, and rituximab for relapsed/refractory …
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: First-in-Human (FIH) Trial of GEN3009 in Subjects With Relapsed or Refractory B-Cell Non-Hodgkin Lymphomas [Phase 1, Phase 2]
First-in-human study of GEN3009 in relapsed or refractory B-cell non-Hodgkin lymphomas was terminated, with results posted thereafter.
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CLINICAL_TRIALS trial_result · 2024-08-12Clinical Trial Update: A Multicentre, Parallel Arm, Open-label Trial of Frontline R-CHOP/Pola-RCHP and Glofitamab in Younger, Higher Risk Patients With Diffuse Large B Cell Lymphoma (DLBCL) [Phase 1, Phase 2]
A multicentre, open-label Phase 1/2 trial is evaluating frontline regimens R-CHOP/Pola-RCHP and Glofitamab in younger patients with high-ris…
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CLINICAL_TRIALS research · 2024-08-12Clinical Trial Update: A Retrospective Study on Extranodal DLBCL
A completed retrospective study examining extranodal diffuse large B-cell lymphoma is reported as an update from Ruijin Hospital.
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: Characterization and Clinical Impact of the Gut Microbiota in Lymphoma
This entry describes a clinical trial investigating how the gut microbiota may influence Diffuse large B-cell lymphoma and its clinical outc…
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CLINICAL_TRIALS research · 2024-08-07Clinical Trial Update: Phase I/IIa Study of BR1733 in Subjects With Advanced Cancers [Phase 1, Phase 2]
Phase I/IIa clinical trial update for BR1733 in advanced cancers, including follicular lymphoma, peripheral T-cell lymphoma, and diffuse lar…
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CLINICAL_TRIALS research · 2024-08-05Clinical Trial Update: The Efficacy and Safety of Pola-ZR2 Versus ZR2 in the Treatment of Old Patients With de Novo Diffuse Large B-cell Lymphoma [Phase 3]
Phase 3 trial comparing Pola-ZR2 to ZR2 in older patients with de Novo Diffuse Large B-Cell Lymphoma; currently recruiting to evaluate effic…
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CLINICAL_TRIALS research · 2024-08-02Clinical Trial Update: Milaberon in Advanced Solid Tumors: an Open, Multicenter Clinical Study [Phase 2]
Open-phase 2 multicenter trial evaluating Milaberon in advanced solid tumors across multiple indications, currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Study of TG-1801 Alone or in Combination With Ublituximab in Subjects With B-Cell Lymphoma or Chronic Lymphocytic Leukemia [Phase 1]
Phase 1 study assessing TG-1801 alone or with ublituximab in patients with CLL, SLL, and other B-cell lymphomas was terminated.
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CLINICAL_TRIALS research · 2024-07-30Clinical Trial Update: Feasibility Study of Induction and Maintenance Avelumab Plus R-CHOP in Patients With Diffuse DLBCL: The AvR-CHOP Study [EARLY_Phase 1]
Feasibility early-phase trial evaluating induction and maintenance therapy with avelumab plus R-CHOP in patients with diffuse large B-cell l…
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CLINICAL_TRIALS research · 2024-07-29Clinical Trial Update: Treatment of Patients With Relapsed or Refractory CD19+ Lymphoid Disease With T Cells Expressing a Third-generation CAR [Phase 1, Phase 2]
A Phase 1/2 clinical trial at University Hospital Heidelberg is evaluating third-generation CD19-directed CAR T cells in relapsed or refract…
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CLINICAL_TRIALS research · 2024-07-29Clinical Trial Update: Molecular Mechanisms in Malignant Lymphoma- Predict (MMML Predict)
MMML Predict is a clinical trial exploring molecular mechanisms in malignant lymphoma, with recruitment ongoing for diffuse large B-cell lym…
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CLINICAL_TRIALS research · 2024-07-25Clinical Trial Update: Evaluate the Safety and Efficacy of Tafasitamab and Lenalidomide in Combination With Gemcitabine and Oxaliplatin Versus Rituximab in Combination With Gemcitabine and Oxaliplatin in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma [Phase 3]
This is a Phase 3 trial evaluating tafasitamab plus lenalidomide with gemcitabine and oxaliplatin versus rituximab with gemcitabine and oxal…
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CLINICAL_TRIALS trial_result · 2024-07-25Clinical Trial Update: Health-Related Quality of Life Outcomes in Patients With Aggressive B-Cell Lymphomas Treated With CAR-T Cell Therapy in Real Life
This clinical trial update discusses health-related quality of life outcomes in patients with aggressive B-cell lymphomas treated with CAR-T…
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CLINICAL_TRIALS research · 2024-07-24Clinical Trial Update: A Study Comparing the Efficacy and Safety of Pola-RCHP-X Versus RCHOP-X and Pola-RCHP in Previously Untreated Patients With DLBCL [Phase 2]
A Phase 2 trial compares Pola-RCHP-X against RCHOP-X and Pola-RCHP in previously untreated diffuse large B-cell lymphoma.
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CLINICAL_TRIALS trial_result · 2024-07-24Clinical Trial Update: An Open-label, Single-arm Study of JWCAR201 in the Treatment of Relapsed or Refractory Diffuse Large B-cell Lymphoma [Phase 1]
This document describes an open-label, single-arm Phase 1 trial evaluating the CAR-T therapy JWCAR201 in patients with relapsed or refractor…