Diffuse Large B-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-10-22Clinical Trial Update: Orelabrutinib in Combination with R-CHOP for CD5-positive DLBCL Patients（Rocket Trial） [Phase 2]
Phase 2 trial evaluating orelabrutinib plus R-CHOP for CD5-positive diffuse large B-cell lymphoma is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: Nivolumab With or Without Varlilumab in Treating Patients With Relapsed or Refractory Aggressive B-cell Lymphomas [Phase 2]
Phase 2 trial evaluating nivolumab with or without varlilumab in relapsed or refractory aggressive B-cell lymphomas, including multiple DLBC…
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: Phase Ib Study to Assess Safety and Preliminary Efficacy of Tafasitamab or Tafasitamab Plus Lenalidomide in Addition to R-CHOP in Patients With Newly Diagnosed DLBCL [Phase 1]
Phase Ib trial assessing safety and preliminary efficacy of tafasitamab alone or with lenalidomide added to R-CHOP in newly diagnosed Diffus…
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CLINICAL_TRIALS research · 2024-10-16Clinical Trial Update: Zanubrutinib and CAR T-cell Therapy for the Treatment of Recurrent or Refractory Aggressive B-cell Non-Hodgkin's Lymphoma or Transformed Indolent B-cell Lymphoma [Phase 2]
Phase 2 trial update on zanubrutinib combined with CAR T-cell therapy for recurrent or refractory aggressive B-cell non-Hodgkin lymphomas an…
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: Axicabtagene Ciloleucel for Consolidation After First-line Treatment of High-risk Large B-cell Lymphoma [Phase 4]
Clinical trial update for consolidation with axicabtagene ciloleucel after first-line treatment in high-risk diffuse large B-cell lymphoma (…
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: A Study of Zilovertamab Vedotin (MK-2140) in Combination With Cyclophosphamide, Doxorubicin, and Prednisone Plus Rituximab or Rituximab Biosimilar (Truxima) (R-CHP) in Participants With Diffuse Large B-Cell Lymphoma (DLBCL) (MK-2140-007) [Phase 2]
Phase 2 clinical trial evaluating Zilovertamab Vedotin in combination with cyclophosphamide, doxorubicin, prednisone plus rituximab or a rit…
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: Golcadomide Post-CAR T-cell in R/R Aggressive Large B-cell Lymphoma Patients With High Risk of Relapse [Phase 2]
Phase 2 trial evaluating Golcadomide after CAR T-cell therapy in adults with relapsed/refractory aggressive diffuse large B-cell lymphoma an…
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: Ibrutinib in Patients With Refractory/Relapsed Non-GCB Diffuse Large B-cell Lymphoma Non-candidates to ASCT [Phase 2]
Phase 2 trial of ibrutinib in patients with refractory/relapsed non-GCB diffuse large B-cell lymphoma who are non-candidates for autologous …
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CLINICAL_TRIALS research · 2024-10-09Clinical Trial Update: Study of Tafasitamab and Lenalinomide Associated to Rituximab in Frontline Diffuse Large B-Cell Lymphoma Patients of 80 y/o or Older [Phase 2]
A Phase 2 clinical trial update describes evaluating a combination of tafasitamab, lenalidomide, and rituximab in frontline diffuse large B-…
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CLINICAL_TRIALS research · 2024-10-09Clinical Trial Update: Pivotal Study to Validate a Novel System to Non-Invasively Detect Severe Neutropenia
Leuko Labs, Inc. is conducting a pivotal study to validate a novel non-invasive system for detecting severe neutropenia. The trial covers Di…
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CLINICAL_TRIALS research · 2024-10-09Clinical Trial Update: Study of Tazemetostat in Newly Diagnosed Diffuse Large B Cell and Follicular Lymphoma Patients Treated by Chemiotherapy [Phase 1, Phase 2]
Update on a Phase 1/Phase 2 study of tazemetostat in newly diagnosed diffuse large B-cell lymphoma and follicular lymphoma treated with chem…
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CLINICAL_TRIALS research · 2024-10-03Clinical Trial Update: A Non-interventional, International, Multicentre Clinical Research Study to Build the Largest Collection of Multimodal Data (Including Clinical Data, Imaging Data and Omics Data) in Oncology
An international non-interventional study sponsored by OWKIN to build a large multimodal oncology data resource (clinical, imaging, and omic…
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CLINICAL_TRIALS trial_result · 2024-09-23Clinical Trial Update: A Study of ABT-199 Plus Ibrutinib and Rituximab in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma [Phase 1]
Phase 1 study evaluating ABT-199 (venetoclax) in combination with ibrutinib and rituximab for relapsed/refractory diffuse large B-cell lymph…
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CLINICAL_TRIALS trial_result · 2024-09-23Clinical Trial Update: Comparison of Point-of-care Produced CAR T-cell with Commercial CAR T-cells in Patients with R/R LBCL [Phase 2]
Phase 2 clinical trial update evaluating point-of-care produced CAR T-cells versus commercial CAR T-cells in patients with relapsed/refracto…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Molecular Subtype-Guided R-CHOP-MTX±Zanubrutinib Treatment in Newly Diagnosed DLBCL Patients with Central Nervous System Involvement [Phase 2]
A Phase 2 trial protocol outlines molecular subtype-guided R-CHOP-MTX with optional zanubrutinib for newly diagnosed diffuse large B-cell ly…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Phase I/II Study of Lenalidomide and Obinutuzumab With CHOP for Diffuse Large B Cell Lymphoma [Phase 1, Phase 2]
Phase I/II study evaluating lenalidomide and obinutuzumab added to CHOP chemotherapy for diffuse large B-cell lymphoma has completed enrollm…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Zanubrutinib and Lenalidomide as Maintenance Therapy in DLBCL [Phase 2]
A Phase 2 clinical trial is evaluating zanubrutinib plus lenalidomide as maintenance therapy in Diffuse Large B-Cell Lymphoma and is current…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: CAR T Cells in the Treatment of Refractory and Relapsed CD19+ B Cell Neoplasms [Phase 1]
Phase 1 trial of CD19-targeted CAR T cells for refractory/relapsed CD19-positive B-cell neoplasms (ALL, mantle cell lymphoma, diffuse large …
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Randomized, Multicenter, Phase III Trial Comparing Treatment With R-mini-CHOP With R-mini-CHP + Polatuzumab Vedotin in Patients With Diffuse Large Cell B Cell Lymphoma [Phase 3]
A randomized Phase III trial compares R-mini-CHOP with R-mini-CHP plus polatuzumab vedotin in diffuse large B-cell lymphoma; the study is cu…
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CLINICAL_TRIALS trial_result · 2024-09-04Clinical Trial Update: Fatigue Reduction Diet in Lymphoma Survivors [NA]
A clinical trial evaluating a Fatigue Reduction Diet for survivors of diffuse large B-cell lymphoma has completed.
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CLINICAL_TRIALS trial_result · 2024-09-03Clinical Trial Update: A Clinical Trial to Learn About the Study Medicine Called Maplirpacept (PF-07901801), Alone and When Used in Combination With Other Medicines to Treat Participants With Advanced Hematological Malignancies, Including Lymphoma, Leukemia and Multiple Myeloma [Phase 1]
Pfizer's Phase 1 trial of Maplirpacept (PF-07901801) in advanced hematologic malignancies, including diffuse large B-cell lymphoma, acute my…
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CLINICAL_TRIALS research · 2024-08-27Clinical Trial Update: Phase I Clinical Trial of RC19D2 Cell Injection in the Treatment of Diffuse Large B-cell Lymphoma [Phase 1]
Phase I clinical trial update for RC19D2 cell injection in recurrent or refractory diffuse large B-cell lymphoma, currently recruiting.
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CLINICAL_TRIALS research · 2024-08-27Clinical Trial Update: A Phase III Clinical Trial of High-dose Rituximab (500mg/m²) Combined With CHOP Regimen in the Treatment of Male Patient With Newly Diagnosed Advanced DLBCL [Phase 3]
A Phase III clinical trial evaluating high-dose rituximab with CHOP as first-line therapy for newly diagnosed advanced diffuse large B-cell …
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CLINICAL_TRIALS research · 2024-08-27Clinical Trial Update: A Real-World Study on Extranodal Lymphoma
A real-world study on extranodal lymphoma is registered at Ruijin Hospital and is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2024-08-26Clinical Trial Update: Polatuzumab Vedotin, Rituximab, Ifosfamide, Carboplatin, and Etoposide (PolaR-ICE) as Initial Salvage Therapy for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma [Phase 2]
Phase 2 study evaluating PolaR-ICE (polatuzumab vedotin, rituximab, ifosfamide, carboplatin, etoposide) as initial salvage therapy for relap…