Diffuse Large B-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-07-24Clinical Trial Update: A Study of Imvotamab Monotherapy and in Combination in Subjects With Relapsed/Refractory Non-Hodgkin Lymphoma [Phase 1, Phase 2]
A Phase 1/Phase 2 study evaluating Imvotamab monotherapy and in combination for relapsed/refractory non-Hodgkin lymphoma has been terminated…
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CLINICAL_TRIALS research · 2024-07-22Clinical Trial Update: Epcoritamab (Epcor)-Containing Combination Salvage Therapy Followed by ASCT & Epcor Consolidation in Patients With Relapsed LBCL [Phase 2]
Phase 2 clinical trial evaluating salvage therapy that includes epcoritamab (Epcor) followed by autologous stem cell transplant and epcorita…
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CLINICAL_TRIALS trial_result · 2024-07-22Clinical Trial Update: Long-term Follow-up Study in Patients Previously Treated With a Mustang Bio CAR-T Cell Investigational Product.
A long-term follow-up update on patients previously treated with Mustang Bio's CAR-T cell investigational product; the trial has been termin…
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CLINICAL_TRIALS trial_result · 2024-07-18Clinical Trial Update: A Study of MS-553 in Patients With Relapsed or Refractory B-cell Lymphoma [Phase 1, Phase 2]
MS-553 trial in relapsed/refractory B-cell lymphomas was terminated after Phase 1/2 studies.
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: A Study of LOXO-305 in Chinese Participants With Blood Cancer (Including Lymphoma and Chronic Leukemia) [Phase 2]
Phase 2 clinical trial update on LOXO-305 (pirtobrutinib) in Chinese participants with B-cell malignancies, with results posted on July 16, …
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CLINICAL_TRIALS trial_result · 2024-07-11Clinical Trial Update: A Study Evaluating the Safety, Efficacy and Pharmacokinetics of Venetoclax in Combination With Polatuzumab Vedotin Plus Rituximab (R) and Cyclophosphamide, Doxorubicin, Prednisone (CHP) in Participants With Untreated BCL-2 Immunohistochemistry (IHC)-Positive Diffuse Large B-Cell Lymphoma (DLBCL) [Phase 1]
This Phase 1 clinical trial update assesses venetoclax with polatuzumab vedotin, rituximab, and CHP in untreated BCL-2 IHC-positive diffuse …
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CLINICAL_TRIALS research · 2024-07-10Clinical Trial Update: Whole-body Diffusion-weighted Magnetic Resonance Imaging for Staging and Treatment Prediction of Lymphoma [NA]
This document provides an update on a clinical trial evaluating whole-body diffusion-weighted MRI for staging and predicting treatment respo…
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CLINICAL_TRIALS trial_result · 2024-07-09Clinical Trial Update: FT596 With Rituximab as Relapse Prevention After Autologous HSCT for NHL [Phase 1]
Phase 1 trial results for FT596 CAR-T cells with Rituximab as relapse prevention after autologous HSCT in non-Hodgkin lymphoma were posted, …
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CLINICAL_TRIALS trial_result · 2024-07-09Clinical Trial Update: Copanlisib With Dose-Adjusted EPOCH-R in Relapsed and Refractory Burkitt Lymphoma and Other High-Grade B-cell Lymphomas [Phase 1]
Phase 1 trial evaluating copanlisib with dose-adjusted EPOCH-R in relapsed and refractory Burkitt lymphoma and other high-grade B-cell lymph…
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CLINICAL_TRIALS trial_result · 2024-07-01Clinical Trial Update: R-ICE and Lenalidomide in Treating Patients With First-Relapse/Primary Refractory Diffuse Large B-Cell Lymphoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating R-ICE chemotherapy in combination with lenalidomide for patients with first-relapse or primary refractory diffuse…
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CLINICAL_TRIALS trial_result · 2024-06-27Clinical Trial Update: Study Evaluating the Safety and Pharmacokinetics of JCAR017 in B-cell Non-Hodgkin Lymphoma (TRANSCEND-NHL-001) [Phase 1]
Phase 1 study evaluating safety and pharmacokinetics of JCAR017 in B-cell non-Hodgkin lymphomas has completed.
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: A-RGEMOX in the Treatment of Early Relapsed/Refractory DLBCL [Phase 2]
A Phase 2 clinical trial evaluating A-RGEMOX for early relapsed/refractory diffuse large B-cell lymphoma is currently recruiting.
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CLINICAL_TRIALS research · 2024-06-21Clinical Trial Update: Biomarker Driven Intensified ChemoImmunotherapy With Early CNS Prophylaxis [Phase 2]
Phase 2 trial update describing biomarker-driven intensified chemo-immunotherapy with early CNS prophylaxis for diffuse large B-cell lymphom…
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CLINICAL_TRIALS research · 2024-06-21Clinical Trial Update: Polatuzumab Vedotin and Zanubrutinib Plus R-CHP for Patients With Newly Diagnosed Untreated Non-GCB DLBCL [Phase 2]
Phase 2 clinical trial evaluating polatuzumab vedotin and zanubrutinib plus R-CHP for newly diagnosed untreated diffuse large B-cell lymphom…
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CLINICAL_TRIALS research · 2024-06-17Clinical Trial Update: Selinexor Plus R-CHOP in High-risk GCB-subtype Diffuse Large B-Cell Lymphoma [Phase 2]
A Phase 2 clinical trial is evaluating the combination of selinexor with R-CHOP for high-risk germinal center B-cell subtype diffuse large B…
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CLINICAL_TRIALS trial_result · 2024-06-13Clinical Trial Update: A Phase Ib Study of YY-20394 in Participants With B-cell Hematologic Malignancies [Phase 1]
Phase Ib study of YY-20394 in participants with B-cell hematologic malignancies has completed, evaluating safety and preliminary activity ac…
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CLINICAL_TRIALS trial_result · 2024-06-11Clinical Trial Update: Study of STRO-001, an Anti-CD74 Antibody Drug Conjugate, in Patients With Advanced B-Cell Malignancies [Phase 1]
Phase 1 study of STRO-001, an anti-CD74 antibody-drug conjugate, in advanced B-cell malignancies has been completed.
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: Efficacy of Pola-RCHP-X vs Pola-RCHP in Untreated DLBCL [Phase 2]
Clinical trial evaluating the efficacy of Pola-RCHP-X versus Pola-RCHP in untreated diffuse large B-cell lymphoma (Phase 2; not yet recruiti…
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CLINICAL_TRIALS research · 2024-06-03Clinical Trial Update: Study of the Hematopoietic Niche and the Role of Inflammation in the Pathophysiology of Cytopenias After CAR-T Cell Therapy: Potential of Therapies Directed to Repair the Bone Marrow Microenvironment
A clinical trial investigating the role of the hematopoietic niche and inflammation in cytopenias after CAR-T cell therapy, exploring therap…
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CLINICAL_TRIALS trial_result · 2024-05-30Clinical Trial Update: A Trial in Patients With Diffuse Large-B-cell Lymphoma Comparing Pixantrone Against Doxorubicin [Phase 2]
Phase 2 trial comparing pixantrone against doxorubicin in patients with diffuse large B-cell lymphoma has completed and results have been po…
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CLINICAL_TRIALS trial_result · 2024-05-30Clinical Trial Update: Imaging Apoptosis for Lymphoma Treatment Response [EARLY_Phase 1]
A Phase 1 trial evaluating imaging apoptosis to monitor treatment response in Diffuse Large B Cell Lymphoma has been terminated.
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Carfilzomib, Rituximab, and Combination Chemotherapy in Treating Patients With Diffuse Large B-Cell Lymphoma [Phase 1, Phase 2]
This trial result updates a Phase 1/2 study evaluating carfilzomib with rituximab and a chemotherapy regimen in adults with diffuse large B-…
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CLINICAL_TRIALS research · 2024-05-23Clinical Trial Update: BCL6-rearrangements Implications in Non-Hodgkin Lymphomas.
This clinical trial update discusses the implications of BCL6 rearrangements across non-Hodgkin lymphomas, including follicular lymphoma, ma…
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CLINICAL_TRIALS research · 2024-05-22Clinical Trial Update: Study to Evaluate the Effectiveness of Tafasitamab in Combination With Lenalidomide Followed by Tafasitamab Monotherapy in Relapsed or Refractory Diffuse Large B-cell Lymphoma Non-transplant Eligible Patients in Italy (PRO-MIND)
Clinical trial evaluating tafasitamab in combination with lenalidomide followed by tafasitamab monotherapy in relapsed or refractory diffuse…
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CLINICAL_TRIALS withdrawal · 2024-05-21Clinical Trial Update: R-DHAP vs POLA-R-DHAP Followed by Autologous Transplant as First Salvage Treatment in Patient With Relapsed or Refractory Diffuse Large B Cell Lymphoma [Phase 2]
A Phase 2 trial comparing R-DHAP versus POLA-R-DHAP followed by autologous transplant for relapsed or refractory diffuse large B-cell lympho…