Diffuse Large B-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: Dynamic CtDNA-guided Targeted Therapy in DLBCL [Phase 2]
A Phase 2 clinical trial evaluating dynamic ctDNA-guided targeted therapy in diffuse large B-cell lymphoma is currently not yet recruiting.
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CLINICAL_TRIALS trial_result · 2024-12-24Clinical Trial Update: A Phase 1/2 Study of CYT-0851 in B-Cell Malignancies and Advanced Solid Tumors [Phase 1, Phase 2]
An update on the Phase 1/2 study of CYT-0851 in B-cell malignancies and advanced solid tumors, noting completion of Phase 1/2 cohorts.
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CLINICAL_TRIALS research · 2024-12-19Clinical Trial Update: Real-World Study of DLBCL With Different Genetic Subtypes
A real-world study of diffuse large B-cell lymphoma across different genetic subtypes is currently recruiting.
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: GPL in Patients with Relapsed/refractory Diffuse Large B Cell Lymphoma [Phase 2]
Phase 2 clinical trial update of GPL in patients with relapsed/refractory diffuse large B-cell lymphoma.
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: The Microbiome in Blood Cancer and HLH
A clinical trial update from University of Nottingham examining the microbiome's role in blood cancers and haemophagocytic lymphohistiocytos…
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: Ibrutinib, Bortezomib and Rituximab-CHOP for the Treatment of Elderly Patients With CD20+ DLBCL, IPI ≥ 2 [Phase 1, Phase 2]
This completed Phase 1/2 trial evaluated the combination of ibrutinib, bortezomib, and Rituximab-CHOP in elderly patients with CD20+ Diffuse…
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CLINICAL_TRIALS trial_result · 2024-12-10Clinical Trial Update: Safety, PK/PD, and Clinical Activity of KT-413 in Adult Patients with Relapsed or Refractory B-cell NHL [Phase 1]
Phase 1 trial update evaluating safety, PK/PD, and clinical activity of KT-413 in adults with relapsed or refractory B-cell non-Hodgkin lymp…
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CLINICAL_TRIALS research · 2024-12-10Clinical Trial Update: realMIND: Observational Study on Safety and Effectiveness of Tafasitamab in Combination With Lenalidomide in Patients With Relapsed or Refractory DLBCL
This ClinicalTrials.gov entry describes the realMIND observational study evaluating the safety and effectiveness of Tafasitamab in combinati…
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: Early Evaluation of the Response of Large B Cell Non Hodgkin's Lymphoma to Chemotherapy by PET/CT [NA]
A completed clinical trial update reporting on early PET/CT-based assessment of chemotherapy response in diffuse large B-cell lymphoma.
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: RadiothErapy priMIng for CAR-T [NA]
Radiotherapy priming for CAR-T therapy in diffuse large B cell lymphoma is listed as an active but not recruiting trial. The entry appears t…
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CLINICAL_TRIALS trial_result · 2024-12-05Clinical Trial Update: Pembrolizumab in Combination With R-ICE Chemotherapy in Relapsed/Refractory Diffuse Large B-cell Lymphoma [Phase 2]
Phase 2 clinical trial evaluating pembrolizumab plus R-ICE chemotherapy as salvage therapy for relapsed/refractory diffuse large B-cell lymp…
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CLINICAL_TRIALS trial_result · 2024-11-21Clinical Trial Update: Safety Study of Rituximab (SC) Administered in Participants With CD20+ DLBCL or CD20+ Follicular NHL Grade 1 to 3A [Phase 3]
Results from a Phase 3 safety study of subcutaneous rituximab in CD20-positive diffuse large B-cell lymphoma or CD20-positive follicular lym…
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CLINICAL_TRIALS research · 2024-11-19Clinical Trial Update: Thrombosis in Diffuse Large B-cell Lymphoma:the PREDIC-TO (PREDICt ThrOmbosis) Study
The PREDIC-TO study is currently recruiting to investigate thrombosis in patients with Diffuse Large B-Cell Lymphoma.
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CLINICAL_TRIALS research · 2024-11-18Clinical Trial Update: RLC Followed by CR-CHOP in Elderly Patients with Newly-diagnosed DEL [Phase 2]
Phase 2 trial evaluating the RLC regimen followed by CR-CHOP in elderly patients with newly diagnosed double-expressor lymphoma. The study s…
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: A Prospective Clinical Study of the Combination Therapy of Obutinib or Decitabine with Rituximab, Cyclophosphamide, and Prednisone for the Primary Treatment of Elderly Patients with Newly Diagnosed Diffuse Large B-cell Lymphoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating Obutinib or Decitabine in combination with Rituximab, Cyclophosphamide, and Prednisone as the primary …
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CLINICAL_TRIALS withdrawal · 2024-11-12Clinical Trial Update: Optimizing Lymphodepletion to Improve Outcomes in Patients Receiving Cell Therapy With Kymriah [Phase 1]
A Phase 1 trial investigating lymphodepletion strategies to improve outcomes in patients with diffuse large B-cell lymphoma treated with Kym…
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CLINICAL_TRIALS research · 2024-11-01Clinical Trial Update: Zanubrutinib-based Maintenance Therapy of Newly Diagnosed DLBCL With Initial Remission [Phase 2]
This clinical trial update describes a Phase 2 study of zanubrutinib-based maintenance therapy in patients with newly diagnosed diffuse Larg…
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CLINICAL_TRIALS trial_result · 2024-10-28Clinical Trial Update: Oral Azacitidine Plus Salvage Chemotherapy in Relapsed/Refractory Diffuse Large B Cell Lymphoma [Phase 1]
Phase 1 trial evaluating the safety of combining oral azacitidine with salvage chemotherapy in patients with relapsed or refractory diffuse …
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CLINICAL_TRIALS trial_result · 2024-10-26Clinical Trial Update: Venetoclax and Selinexor in Treating Patients with Relapsed or Refractory High Risk Hematologic Malignancies [Phase 1]
This Phase 1 trial evaluated the combination of venetoclax and selinexor in relapsed or refractory high-risk hematologic malignancies, inclu…
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CLINICAL_TRIALS research · 2024-10-24Clinical Trial Update: The Effectiveness and Safety of Glofitamab in Real-World Clinical Practice Among Chinese Adult Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma: A Prospective, Observational, Multicenter Study
A prospective, multicenter observational study in China assessing the real-world effectiveness and safety of glofitamab in adults with relap…
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CLINICAL_TRIALS research · 2024-10-23Clinical Trial Update: Autologous Hematopoietic Stem Cell Boost Study After CAR-T Therapy [Phase 2]
A Phase 2 clinical trial is evaluating autologous hematopoietic stem cell boost after CAR-T therapy in patients with diffuse large B-cell ly…
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CLINICAL_TRIALS research · 2024-10-23Clinical Trial Update: Novel Targeted Drugs Combined With R-ICE Regimen in Relapsed and Refractory Diffuse Large B-cell Lymphoma [Phase 2]
Phase 2 study evaluating novel targeted drugs combined with the R-ICE regimen for relapsed or refractory diffuse large B-cell lymphoma; curr…
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CLINICAL_TRIALS research · 2024-10-22Clinical Trial Update: Mechanism Investigation of R-CHOP Regimen or Tucidinostat Plus R-CHOP (CR-CHOP) Regimen in the Treatment of BCL2/MYC Protein Double Expressor Lymphoma
Clinical trial update from Ruijin Hospital outlines a mechanism investigation of R-CHOP alone or in combination with tucidinostat for treati…
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CLINICAL_TRIALS trial_result · 2024-10-22Clinical Trial Update: Zanubrutinib Combined With BEAM for ASCT in Relapsed and Refractory DLBCL [Phase 2]
Phase 2 clinical trial evaluating zanubrutinib in combination with BEAM conditioning for autologous stem cell transplantation in relapsed or…
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CLINICAL_TRIALS trial_result · 2024-10-22Clinical Trial Update: Selinexor Combined With BEAM for ASCT in R/R DLBCL With MYC Positive [Phase 2]
A Phase 2 clinical trial is evaluating selinexor in combination with BEAM conditioning for autologous stem cell transplantation in relapsed/…