Diffuse Intrinsic Pontine Glioma
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: International Diffuse Intrinsic Pontine Glioma (DIPG)/Diffuse Midline Glioma (DMG) Registry and Repository
An international DIPG/DMG Registry and Repository study is currently recruiting to collect data and biospecimens for diffuse intrinsic ponti…
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Effect of Antineoplaston Therapy on the QT/QTc Interval In Subjects With Diffuse, Intrinsic, Brainstem Glioma [Phase 3]
Phase 3 trial evaluating the effect of antineoplaston therapy on QT/QTc interval in patients with diffuse intrinsic pontine glioma.
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B) [Phase 1]
Phase 1 clinical trial update for C7R-GD2.CAR T cells targeting GD2-expressing brain tumors, currently recruiting for DIPG, high-grade gliom…
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: Atovaquone Combined With Radiation in Children With Malignant Brain Tumors [Phase 1]
A Phase 1 clinical trial evaluating atovaquone in combination with radiation for pediatric malignant brain tumors is currently recruiting.
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Fimepinostat in Treating Brain Tumors in Children and Young Adults [EARLY_Phase 1]
This is an early-phase 1 trial update on fimepinostat for pediatric and young adult brain tumors, including DIPG, recurrent anaplastic astro…
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: A Study of Low Dose Bevacizumab With Conventional Radiotherapy Alone in Diffuse Intrinsic Pontine Glioma [Phase 2]
A Phase 2 clinical trial is investigating low-dose bevacizumab with conventional radiotherapy for diffuse intrinsic pontine glioma. The stud…
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: Safety and Efficacy of Loco-regional B7H3 IL-7Ra CAR T Cell in DIPG [Phase 1]
Phase 1 trial evaluating the safety and early efficacy of loco-regional B7H3 IL-7Ra CAR T cells for diffuse intrinsic pontine glioma (DIPG) …
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CLINICAL_TRIALS research · 2025-02-21Clinical Trial Update: Study of Olutasidenib and Temozolomide in HGG [Phase 2]
Phase 2 study evaluating olutasidenib in combination with temozolomide for high-grade gliomas is currently recruiting.
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: GD2-CAR T Cells for Pediatric Brain Tumours [Phase 1]
Phase 1 trial evaluating GD2-CAR T cells for pediatric brain tumors is currently recruiting. The study targets medulloblastoma, embryonal tu…
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CLINICAL_TRIALS research · 2025-01-14Clinical Trial Update: Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumors [Phase 2]
Phase 2 pediatric trial evaluating palbociclib in combination with chemotherapy for recurrent or refractory solid tumors, including Ewing sa…
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: Clinical Trial to Assess the Safety and Efficacy of AloCELYVIR With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) in Combination With Radiotherapy or Medulloblastoma in Monotherapy [Phase 1, Phase 2]
Clinical trial evaluating AloCELYVIR for newly diagnosed diffuse intrinsic pontine glioma in combination with radiotherapy and pediatric med…
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CLINICAL_TRIALS research · 2024-08-20Clinical Trial Update: Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma
A clinical trial update describing molecular analyses of samples from patients with diffuse intrinsic pontine glioma and brainstem glioma to…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Adjuvant Dendritic Cell Immunotherapy for Pediatric Patients With High-grade Glioma or Diffuse Intrinsic Pontine Glioma [Phase 1, Phase 2]
Phase 1/2 trial evaluating adjuvant dendritic cell immunotherapy in pediatric high-grade glioma and diffuse intrinsic pontine glioma; the st…
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CLINICAL_TRIALS research · 2024-05-02Clinical Trial Update: Clinical Study of Allogeneic Vγ9Vδ2 T Cells in the Treatment of Brain Malignant Glioma [EARLY_Phase 1]
This entry describes an early-stage Phase 1 clinical study evaluating allogeneic Vγ9Vδ2 T cells for malignant gliomas, including glioblastom…
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CLINICAL_TRIALS research · 2024-04-30Clinical Trial Update: xPedite: A Study to Expedite DIPG and DMG Research
The sponsor xCures reports a clinical trial called xPedite to expedite DIPG and DMG research. The study is currently recruiting.
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CLINICAL_TRIALS research · 2022-10-20Clinical Trial Update: Diffuse Intrinsic Pontine Glioma (DIPG) Reirradiation (ReRT) [Phase 1, Phase 2]
Phase 1/2 clinical trial update on reirradiation for diffuse intrinsic pontine glioma (DIPG) is completed.
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CLINICAL_TRIALS research · 2018-07-23Clinical Trial Update: Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication [Phase 2]
An update on a Phase 2 clinical trial evaluating a biological medicine for Diffuse Intrinsic Pontine Glioma. The current status of the trial…
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CLINICAL_TRIALS research · 2018-03-02Clinical Trial Update: Safety Study of DIPG Treatment With Autologous Dendritic Cells Pulsed With Lysated Allegenic Tumor Lines [Phase 1]
Phase 1 safety study evaluating autologous dendritic cells pulsed with lysed allogeneic tumor lines for Diffuse Intrinsic Pontine Glioma (DI…
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CLINICAL_TRIALS research · 2016-09-13Clinical Trial Update: Anti PD1 Antibody in Diffuse Intrinsic Pontine Glioma [Phase 1, Phase 2]
This entry reports a Phase 1/Phase 2 clinical trial evaluating an anti-PD-1 antibody in diffuse intrinsic pontine glioma; no trial results a…