Cystic Fibrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-03Clinical Trial Update: Restarting Triple Therapy With Robust Monitoring for Adverse Events (RETRIAL)
A cystic fibrosis clinical trial is restarting a triple-drug therapy with enhanced monitoring for adverse events. The study is currently rec…
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CLINICAL_TRIALS research · 2025-11-03Clinical Trial Update: Prospective Study of Pregnancy in Women With Cystic Fibrosis
This clinical trial update covers a prospective study of pregnancy in women with cystic fibrosis, currently listed as active but not recruit…
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CLINICAL_TRIALS research · 2025-11-03Clinical Trial Update: The PROMISE Pediatric Study 6 to 11 Years Old
This clinical trial update reports on the PROMISE pediatric study for children aged 6 to 11 with cystic fibrosis, noting the study is curren…
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CLINICAL_TRIALS research · 2025-10-31Clinical Trial Update: Gastrointestinal Response of Pediatric Cystic Fibrosis Patients on Mediterranean Diet [NA]
A pediatric cystic fibrosis trial is evaluating gastrointestinal response to a Mediterranean diet; the study is currently not recruiting.
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EMA approval · 2025-10-30EMA Authorised: Orkambi (Lumacaftor;ivacaftor) — Vertex Pharmaceuticals (Ireland) Limited
The European Medicines Agency authorised Orkambi (lumacaftor/ivacaftor) for cystic fibrosis, with Vertex Pharmaceuticals (Ireland) Limited a…
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CLINICAL_TRIALS trial_result · 2025-10-30Clinical Trial Update: Pragmatic Implementation Trial of a CF Primary Palliative Care Intervention [NA]
The trial registry shows a completed pragmatic implementation trial of a primary palliative care intervention for cystic fibrosis.
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CLINICAL_TRIALS research · 2025-10-30Clinical Trial Update: Skeletal Health and Bone Marrow Composition in Adolescents With Cystic Fibrosis
A clinical trial is examining skeletal health and bone marrow composition in adolescents with cystic fibrosis. The study is currently recrui…
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CLINICAL_TRIALS research · 2025-10-28Clinical Trial Update: Effect of Losartan in Cystic Fibrosis (CF)-NIH Grant #133240 [EARLY_Phase 1]
An early-phase clinical trial update describes evaluating Losartan in cystic fibrosis; the study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-10-24Clinical Trial Update: Acoustic Waveform Respiratory Evaluation [NA]
This clinical trial evaluates acoustic waveform respiratory assessment across several respiratory diseases and is currently recruiting.
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: Prospective Healthcare-Associated Links in Transmission of Nontuberculous Mycobacteria
Enrollment is ongoing for a prospective study examining healthcare-associated transmission of nontuberculous mycobacteria, including partici…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Mapping Chemical and Microbiological Heterogeneity Throughout Explanted Cystic Fibrosis Lung Specimens
This clinical trial update describes a study mapping chemical and microbiological heterogeneity across explanted cystic fibrosis lung specim…
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CLINICAL_TRIALS research · 2025-10-10Clinical Trial Update: CHaractErizing CFTR Modulated Changes in Sweat Chloride and Their Association With Clinical Outcomes
A clinical trial update investigating CFTR-modulated changes in sweat chloride and how they relate to clinical outcomes in cystic fibrosis; …
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CLINICAL_TRIALS research · 2025-10-09Clinical Trial Update: Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis [Phase 2]
This clinical trial update describes a Phase 2 study of ARCT-032 to assess safety, tolerability, and efficacy in people with cystic fibrosis…
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CLINICAL_TRIALS trial_result · 2025-10-06Clinical Trial Update: Evaluation of Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) in Cystic Fibrosis (CF) Participants 12 to Less Than 24 Months of Age [Phase 3]
A Phase 3 trial evaluating the cystic fibrosis triple combination Elexacaftor/Tezacaftor/Ivacaftor in participants aged 12 to less than 24 m…
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CLINICAL_TRIALS trial_result · 2025-10-06Clinical Trial Update: Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis Participants 12 Months of Age and Older [Phase 3]
Phase 3 trial update describing long-term safety and efficacy of the cystic fibrosis triple combination ELX/TEZ/IVA in participants aged 12 …
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: CFTR Modulator Effects on Bone and Muscle in Adults With Cystic Fibrosis
This clinical trial update reports on studying the effects of CFTR modulator therapy on bone density and muscle in adults with cystic fibros…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Development Of An Innovative Panel of Methods To Measure Intestinal Macronutrient Digestion, Absorption, and Function [NA]
This clinical trial update outlines an innovative panel of methods to measure intestinal macronutrient digestion, absorption, and function, …
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Remote Sputum Collection in Cystic Fibrosis
A University of Pennsylvania-sponsored trial on remote sputum collection in patients with cystic fibrosis is currently recruiting to study i…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators
This clinical trial update describes a study to advance the cystic fibrosis therapeutic pipeline for people not using modulators, which is c…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: IV Gallium Study for Patients With Cystic Fibrosis Who Have NTM (ABATE Study) [Phase 1]
A Phase 1 trial evaluating intravenous gallium in cystic fibrosis patients with nontuberculous mycobacterial infection is currently recruiti…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: A Study of Females With CF Throughout Pregnancy and Post-partum, and Follow up of Their Offspring
ClinicalTrials.gov entry for a study of women with cystic fibrosis during pregnancy and postpartum, with follow-up of their offspring; the s…
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: Sinus Disease in Young Children With Cystic Fibrosis
A UCLA-led clinical trial investigating sinus disease in young children with cystic fibrosis is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-09-26Clinical Trial Update: A Study To Evaluate the Relative Bioavailability, Food Effect, and Dose Proportionality of a Granule Formulation of Vanzacaftor/Tezacaftor/Deutivacaftor(VNZ/TEZ/D-IVA) [Phase 1]
Phase 1 study evaluating relative bioavailability, food effect, and dose proportionality of a granule formulation of Vanzacaftor/Tezacaftor/…
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FDA approval · 2025-09-25FDA Approved: TRIKAFTA — Supplemental Application (Vertex Pharmaceuticals Incorporated)
The FDA approved a supplemental application for TRIKAFTA (elexacaftor/tezacaftor/ivacaftor) from Vertex Pharmaceuticals Incorporated. This a…
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FDA approval · 2025-09-25FDA Approved: TRIKAFTA — Supplemental Application (Vertex Pharmaceuticals Incorporated)
FDA approved a supplemental application for TRIKAFTA (elexacaftor/tezacaftor/ivacaftor) from Vertex Pharmaceuticals, updating its regulatory…