Cystic Fibrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-01-07Clinical Trial Update: Flaxseed Modulates Inflammation and Oxidative Stress in CF [Phase 1]
This update reports the completion of a Phase 1 trial evaluating flaxseed's effects on inflammation and oxidative stress in cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2013-12-27Clinical Trial Update: Study Evaluating Fosfomycin/Tobramycin for Inhalation in Cystic Fibrosis Patients With Pseudomonas Aeruginosa Lung Infection [Phase 2]
A Phase 2 trial evaluating inhaled fosfomycin/tobramycin for cystic fibrosis patients with Pseudomonas aeruginosa lung infection has complet…
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FDA approval · 2013-12-13FDA Approved: KALYDECO — Supplemental Application (Vertex Pharmaceuticals Incorporated)
The FDA approved a supplemental application for KALYDECO (ivacaftor) submitted by Vertex Pharmaceuticals Incorporated. This action represent…
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CLINICAL_TRIALS trial_result · 2013-12-13Clinical Trial Update: Fecal Calprotectin in Cystic Fibrosis
A completed clinical trial sponsored by the Medical College of Wisconsin evaluated fecal calprotectin in patients with cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2013-12-12Clinical Trial Update: Alpha1 Antitrypsin Aerosol Therapy in Cystic Fibrosis [Phase 2]
A Phase 2 trial of inhaled alpha-1 antitrypsin therapy for cystic fibrosis was terminated.
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FDA approval · 2013-12-09FDA Approved: ZENPEP — Supplemental Application (Aimmune Therapeutics, Inc.)
FDA approved a supplemental application for ZENPEP (pancrelipase) submitted by Aimmune Therapeutics.
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CLINICAL_TRIALS trial_result · 2013-12-09Clinical Trial Update: Evaluation of Regional Ventilation Using 19F MRI of Inert Perfluorinated Gases Mixed With Oxygen [Phase 1]
Phase 1 clinical trial evaluating regional ventilation using 19F MRI with inert perfluorinated gases mixed with oxygen in patients with COPD…
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CLINICAL_TRIALS trial_result · 2013-12-05Clinical Trial Update: Non-invasive Ventilation and Oxygen Therapy in Cystic Fibrosis Patients With Nocturnal Oxygen Desaturation [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating non-invasive ventilation and supplemental oxygen in cystic fibrosis patients with nocturnal oxygen des…
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CLINICAL_TRIALS research · 2013-11-28Clinical Trial Update: Prevalence and Treatment of Urinary Incontinence in Women With Cystic Fibrosis and Chronic Obstructive Pulmonary Disease [NA]
A completed clinical trial reporting on the prevalence of urinary incontinence in women with cystic fibrosis and chronic obstructive pulmona…
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CLINICAL_TRIALS trial_result · 2013-11-21Clinical Trial Update: Cipro Inhaler for Cystic Fibrosis Children Ages 6-12 [Phase 1]
A Phase 1 clinical trial evaluating inhaled ciprofloxacin (Cipro Inhaler) in children with cystic fibrosis has completed.
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CLINICAL_TRIALS trial_result · 2013-11-19Clinical Trial Update: Effects Of Noninvasive Ventilation On Functional Capacity Of Patients With Cystic Fibrosis [NA]
A completed clinical trial evaluated the effects of noninvasive ventilation on functional capacity in patients with cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2013-11-19Clinical Trial Update: Exercise-Induced Bronchospasm in Cystic Fibrosis
This clinical trials update notes that a study examining exercise-induced bronchospasm in cystic fibrosis has completed.
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CLINICAL_TRIALS trial_result · 2013-11-15Clinical Trial Update: A Phase 1 Study to Examine the Drug-Drug Interaction of Ciprofloxacin, Itraconazole, and Rifampin on the Combination of Lumacaftor With Ivacaftor in Healthy Adult Subjects [Phase 1]
A Phase 1 pharmacokinetic study evaluating potential drug-drug interactions between lumacaftor/ivacaftor and ciprofloxacin, itraconazole, an…
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CLINICAL_TRIALS trial_result · 2013-11-07Clinical Trial Update: Comparison of Two Treatment Regimens to Reduce PA Infection in Children With Cystic Fibrosis [Phase 2]
Phase 2 clinical trial comparing two regimens to reduce Pseudomonas aeruginosa infection in children with cystic fibrosis. The study is comp…
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CLINICAL_TRIALS trial_result · 2013-11-07Clinical Trial Update: Self-dispersing Liquids as Aerosol Drug Carriers [NA]
A completed clinical trial evaluating self-dispersing liquids as aerosol drug carriers for cystic fibrosis has posted results.
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CLINICAL_TRIALS trial_result · 2013-10-31Clinical Trial Update: Efficacy and Safety of 24 Weeks of Oral Treatment With BIIL 284 BS in Adult and Pediatric Patients [Phase 2]
Phase 2 study evaluating 24 weeks of oral BIIL 284 BS in adults and pediatric cystic fibrosis patients reported on efficacy and safety; the …
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FDA approval · 2013-10-24FDA Approved: TOBI — Supplemental Application (Viatris Specialty LLC)
The FDA approved a supplemental application for TOBI (tobramycin inhalation solution) submitted by Viatris Specialty LLC.
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CLINICAL_TRIALS trial_result · 2013-10-14Clinical Trial Update: Probiotics on Intestinal Inflammation in Cystic Fibrosis [Phase 3]
A Phase 3 trial evaluating probiotics for intestinal inflammation in cystic fibrosis has completed.
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FDA approval · 2013-09-26FDA Approved: TOBI — Supplemental Application (Viatris Specialty LLC)
The FDA approved a supplemental application for TOBI (tobramycin) submitted by Viatris Specialty LLC.
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CLINICAL_TRIALS trial_result · 2013-09-17Clinical Trial Update: High Volumes of Hypertonic Saline and Chest Physiotherapy in CF Patients [NA]
This clinical trial update notes a completed study evaluating high volumes of hypertonic saline with chest physiotherapy in patients with cy…
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CLINICAL_TRIALS trial_result · 2013-09-05Clinical Trial Update: Bacteriophage Effects on Pseudomonas Aeruginosa [NA]
Completed clinical trial evaluating bacteriophage therapy against Pseudomonas aeruginosa in people with cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2013-09-04Clinical Trial Update: Improving Adherence and Clinical Outcome in Cystic Fibrosis (CF) Patients [NA]
Completed clinical trial from Sheba Medical Center aimed at improving adherence and outcomes in cystic fibrosis patients. The study status i…
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CLINICAL_TRIALS trial_result · 2013-09-02Clinical Trial Update: The Short Term Safety and Efficacy of Inhaled L-arginine in Patients With Cystic Fibrosis [Phase 2]
This Phase 2 study reports on the short-term safety and efficacy of inhaled L-arginine in patients with cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2013-09-02Clinical Trial Update: The Effect of Hypertonic Saline on the Lung Clearance Index in Patients With Cystic Fibrosis [Phase 3]
Phase 3 trial evaluating the effect of inhaled hypertonic saline on the lung clearance index in patients with cystic fibrosis; the study sta…
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CLINICAL_TRIALS trial_result · 2013-09-02Clinical Trial Update: Utility of Induced Sputum Using Hypertonic Saline to Evaluate Infection and Inflammation in Cystic Fibrosis [Phase 2]
Phase 2 clinical trial evaluating whether induced sputum using hypertonic saline can evaluate infection and inflammation in cystic fibrosis.