Cystic Fibrosis
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Sign up freeTop drugs studied for this disease
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FDA approval · 2016-12-19FDA Approved: ZENPEP — Supplemental Application (Aimmune Therapeutics, Inc.)
The FDA approved a supplemental application for ZENPEP (pancrelipase) submitted by Aimmune Therapeutics, Inc.
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FDA approval · 2016-12-16FDA Approved: TOBI PODHALER — Supplemental Application (Viatris Specialty LLC)
FDA approved a supplemental application for TOBI PODHALER (tobramycin inhalation powder) by Viatris Specialty LLC.
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CLINICAL_TRIALS trial_result · 2016-12-09Clinical Trial Update: Backpack Carrying in Children With Cystic Fibrosis [Phase 4]
A Phase 4 clinical trial evaluating backpack carrying in children with cystic fibrosis has completed.
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CLINICAL_TRIALS trial_result · 2016-12-07Clinical Trial Update: Study of GLPG1837 in Subjects With Cystic Fibrosis (G551D Mutation) [Phase 2]
The Phase 2 study of GLPG1837 in cystic fibrosis patients with the G551D mutation has completed.
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CLINICAL_TRIALS trial_result · 2016-12-05Clinical Trial Update: Study of Lumacaftor in Combination With Ivacaftor in Subjects 6 Through 11 Years of Age With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation [Phase 3]
A Phase 3 study of lumacaftor in combination with ivacaftor in children aged 6 through 11 with cystic fibrosis homozygous for the F508del-CF…
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CLINICAL_TRIALS trial_result · 2016-12-01Clinical Trial Update: Early Intervention in Pulmonary Exacerbation in Cystic Fibrosis [NA]
An update for the early intervention in pulmonary exacerbation in cystic fibrosis trial (NCT00850551) shows the study has completed.
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CLINICAL_TRIALS research · 2016-11-21Clinical Trial Update: Study of Cavosonstat (N91115) in CF Patients Who Are Heterozygous for F508del-CFTR and a Gating Mutation and Being Treated With Ivacaftor [Phase 2]
Phase 2 clinical trial update on cavosonstat (N91115) in cystic fibrosis patients who are heterozygous for F508del-CFTR and a gating mutatio…
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FDA approval · 2016-11-18FDA Approved: TOBRAMYCIN INHALATION SOLUTION PAK — Supplemental Application (Genericus, Inc.)
The FDA approved a supplemental application for Tobramycin Inhalation Solution PAK by Genericus, Inc., enabling a generic tobramycin inhalat…
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CLINICAL_TRIALS trial_result · 2016-11-15Clinical Trial Update: Resistive Inspiratory Manoeuvre as Airway Clearance Technique in Cystic Fibrosis [NA]
The document notes a completed clinical trial investigating a resistive inspiratory manoeuvre as an airway clearance technique for cystic fi…
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CLINICAL_TRIALS trial_result · 2016-11-11Clinical Trial Update: High Frequency Chest Wall Oscillation and Cystic Fibrosis [Phase 3]
Phase 3 trial evaluating high frequency chest wall oscillation for cystic fibrosis has completed.
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CLINICAL_TRIALS trial_result · 2016-11-07Clinical Trial Update: Study of N91115 in Patients With Cystic Fibrosis Homozygous F508del-CFTR Mutation [Phase 1]
A Phase 1 trial evaluating N91115 in cystic fibrosis patients with homozygous F508del-CFTR mutation has completed.
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CLINICAL_TRIALS trial_result · 2016-11-07Clinical Trial Update: PK Study of N91115 in Cystic Fibrosis Patients [Phase 1]
Phase 1 pharmacokinetic study of N91115 in cystic fibrosis patients has completed.
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CLINICAL_TRIALS trial_result · 2016-10-26Clinical Trial Update: Pilot Observational Study to Determine Feasibility of a Standardized Treatment of Pulmonary Exacerb. in Patients With CF
A completed pilot observational study assessing the feasibility of a standardized treatment approach for pulmonary exacerbations in patients…
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CLINICAL_TRIALS trial_result · 2016-10-25Clinical Trial Update: Investigating the Use of a Positive Parenting Programme to Improve Treatment Adherence in Cystic Fibrosis [NA]
A completed clinical trial update investigating whether a Positive Parenting Programme can improve treatment adherence in cystic fibrosis.
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CLINICAL_TRIALS research · 2016-10-25Clinical Trial Update: Longitudinal Pathogen-colonization in Cystic Fibrosis Airways and Ability to Smell
A University of Jena clinical trial update examines longitudinal pathogen colonization in cystic fibrosis airways and the sense of smell, wi…
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CLINICAL_TRIALS trial_result · 2016-10-24Clinical Trial Update: Bioavailability and Pharmacokinetics Study of FDL169 in Healthy Subjects and Subjects With Cystic Fibrosis [Phase 1, Phase 2]
A Phase 1/Phase 2 bioavailability and pharmacokinetics study of the investigational drug FDL169 completed in healthy subjects and individual…
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CLINICAL_TRIALS trial_result · 2016-10-11Clinical Trial Update: Study of GLPG1837 in Subjects With Cystic Fibrosis (S1251N Mutation) [Phase 2]
A Phase 2 clinical trial evaluating GLPG1837 in cystic fibrosis patients with the S1251N mutation has completed.
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CLINICAL_TRIALS trial_result · 2016-10-11Clinical Trial Update: Pharmacokinetic Study of Aerosolized Colimycin in Cystic Fibrosis [Phase 1]
Phase 1 pharmacokinetic study of aerosolized Colimycin in patients with cystic fibrosis has completed, evaluating lung and systemic exposure…
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FDA approval · 2016-10-06FDA Approved: PERTZYE — Supplemental Application (Digestive Care, Inc.)
FDA Supplemental Application for PERTZYE (pancrelipase) submitted by Digestive Care, Inc. under BLA022175. The submission pertains to a supp…
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CLINICAL_TRIALS trial_result · 2016-10-04Clinical Trial Update: The Challenge of Obtaining Qualitative Bacterial Cultures in Non-expectorating Cystic Fibrosis Patients
This clinical trial update discusses the challenges of obtaining qualitative bacterial cultures from non-expectorating cystic fibrosis patie…
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FDA approval · 2016-09-28FDA Approved: ORKAMBI — Supplemental Application (Vertex Pharmaceuticals Incorporated)
FDA approved a supplemental application for ORKAMBI (lumacaftor and ivacaftor) submitted by Vertex Pharmaceuticals Incorporated.
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CLINICAL_TRIALS research · 2016-09-28Clinical Trial Update: Study to Evaluate the Safety,Tolerability, Pharmacokinetics and Exploratory Efficacy Parameters of AIR DNase™in Patients With Cystic Fibrosis Previously Treated With Pulmozyme® [Phase 2]
Phase 2 clinical trial update evaluating safety, tolerability, pharmacokinetics, and exploratory efficacy of AIR DNase in cystic fibrosis pa…
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CLINICAL_TRIALS trial_result · 2016-09-23Clinical Trial Update: Measurement of Lung Water by Transpulmonary Thermodilution in Lung Transplanted Patients
This update reports results from a clinical trial measuring lung water using transpulmonary thermodilution in patients who have received lun…
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CLINICAL_TRIALS research · 2016-09-20Clinical Trial Update: Adherence to Airway Clearance. Novel Approaches to Improving Adherence [NA]
This entry reports an ongoing clinical trial focused on improving adherence to airway clearance techniques in people with cystic fibrosis an…
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CLINICAL_TRIALS trial_result · 2016-09-08Clinical Trial Update: Cystic Fibrosis Treatment Adherence Cayston Proof-of-Concept Pilot Study
A completed proof-of-concept pilot study evaluated adherence to Cayston (aztreonam for inhalation) therapy in cystic fibrosis patients.